CD4+/CD8+ double-positive T cells: more than just a developmental stage? (Q26821885)

title

CD4+/CD8+ double-positive T cells: more than just a developmental stage? (English)

1 reference

1

1 reference

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7 June 2020

Raymond J Steptoe

series ordinal

3

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7 June 2020

author name string

Ji-Won Jung

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25360000%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

James W Wells

series ordinal

4

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7 June 2020

language of work or name

1 reference

January 2015

1 reference

Journal of Leukocyte Biology

published in

2 references

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7 June 2020

volume

97

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7 June 2020

issue

1

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7 June 2020

page(s)

31-38

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A role for IL-5 in the induction of cytotoxic T lymphocytes in vivo

7 June 2020

cites work

1 reference

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7 January 2021

CD4(+)CD8(dim) T lymphocytes exhibit enhanced cytokine expression, proliferation and cytotoxic activity in response to HCMV and HIV-1 antigens.

1 reference

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7 January 2021

Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis

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7 January 2021

Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes

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7 January 2021

T cell receptor/CD3 complex internalization following activation of a cytolytic T cell clone: evidence for a protein kinase C-independent staurosporine-sensitive step

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7 January 2021

Co-expression of CD8 alpha in CD4+ T cell receptor alpha beta + T cells migrating into the murine small intestine epithelial layer.

1 reference

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7 January 2021

A novel peripheral CD4+ CD8+ T cell population: inheritance of CD8alpha expression on CD4+ T cells

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7 January 2021

CD8 alpha is an activation marker for a subset of peripheral CD4 T cells

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7 January 2021

Increased frequency of nonconventional double positive CD4CD8 alphabeta T cells in human breast pleural effusions.

1 reference

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7 January 2021

Tumor-reactive CD4+ CD8αβ+ CD103+ αβT cells: a prevalent tumor-reactive T-cell subset in metastatic colorectal cancers.

1 reference

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7 January 2021

Emergence of double-positive CD4/CD8 cells from adult peripheral blood mononuclear cells infected with human T cell leukemia virus type I (HTLV-I).

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7 January 2021

Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cell-based therapies and studies related to the expansion of double-positive T-cells during aging

1 reference

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7 January 2021

Phenotypic heterogeneity of persistent expansions of CD4+ CD8+ T cells

1 reference

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7 January 2021

Role of IL-13 in regulation of anti-tumor immunity and tumor growth

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7 January 2021

CD4+ CD8+ cells are rare among in vitro activated mouse or human T lymphocytes

1 reference

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7 January 2021

Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs

1 reference

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7 January 2021

CD4+ CD8+ double positive (DP) T cells in health and disease

1 reference

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7 January 2021

Spatial coordination of CD8 and TCR molecules controls antigen recognition by CD8+ T-cells.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Structural and mutational analyses of a CD8alphabeta heterodimer and comparison with the CD8alphaalpha homodimer

1 reference

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7 January 2021

The zinc finger transcription factor Zbtb7b represses CD8-lineage gene expression in peripheral CD4+ T cells

1 reference

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7 January 2021

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1 reference

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7 January 2021

CD4, CD8 and TCR defined T-cell subsets in thymus and spleen of 2- and 7-week old commercial broiler chickens

1 reference

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7 January 2021

Extrathymic CD4/CD8 double positive T cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Co-expression of the CD8 receptor in a human CD4+ T-cell clone influences proliferation, cytosolic Ca2+ release and cytokine production

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Cloned suppressor T cells from a lepromatous leprosy patient suppress Mycobacterium leprae reactive helper T cells

1 reference

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7 January 2021

NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

1 reference

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7 January 2021

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

T-cell development and the CD4-CD8 lineage decision

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD4+ CD8+ (thymocyte-like) T lymphocytes present in blood and skin from patients with atopic dermatitis suggest immune dysregulation

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Functional and phenotypic analysis of porcine peripheral blood CD4/CD8 double-positive T cells.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Distribution of porcine CD4/CD8 double-positive T lymphocytes in mucosa-associated lymphoid tissues

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Phenotypic analysis of peripheral CD4+ CD8+ T cells in the rat

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Upregulation of CD4 on CD8+ T cells: CD4dimCD8bright T cells constitute an activated phenotype of CD8+ T cells.

1 reference

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7 January 2021

1 reference

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7 January 2021

CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

An important regulatory role for CD4 + CD8αα T cells in the intestinal epithelial layer in the prevention of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

An immunoregulatory function for the CD8 molecule

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Activation of CD8+ T lymphocytes through the T cell receptor turns on CD4 gene expression: implications for HIV pathogenesis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Expression, purification, and functional analysis of murine ectodomain fragments of CD8alphaalpha and CD8alphabeta dimers

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD1d-restricted human natural killer T cells are highly susceptible to human immunodeficiency virus 1 infection

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Persistent expansion, in a human immunodeficiency virus-infected person, of V beta-restricted CD4+CD8+ T lymphocytes that express cytotoxicity-associated molecules and are committed to produce interferon-gamma and tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Peripheral blood CD4+CD8+ lymphocytes in cynomolgus monkeys are of resting memory T lineage.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD4dullCD8bright double-positive T-lymphocytes have a phenotype of granzyme Bpos CD8pos memory T-lymphocytes

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Epicutaneous immunization induces alphabeta T-cell receptor CD4 CD8 double-positive non-specific suppressor T cells that inhibit contact sensitivity via transforming growth factor-beta.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Expression of CD8alpha identifies a distinct subset of effector memory CD4+ T lymphocytes.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Extrathymic CD4+CD8+ lymphocytes in Chagas disease: possible relationship with an immunoendocrine imbalance.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Expansion of a novel pulmonary CD3(-) CD4(+) CD8(+) cell population in mice during Chlamydia pneumoniae infection

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Peripheral NKT cells in simian immunodeficiency virus-infected macaques

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Simian immunodeficiency virus infection of CD8+ lymphocytes in vivo

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Mechanisms of T cell development and transformation.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Positive and negative selection of T cells

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

The role of ThPOK in control of CD4/CD8 lineage commitment

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD8+ T cells that express CD4 on their surface (CD4dimCD8bright T cells) recognize an antigen-specific target, are detected in vivo, and can be productively infected by T-tropic HIV.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Peripheral CD4(+)CD8(+) T cells are differentiated effector memory cells with antiviral functions.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD4+/CD8+ macrophages infiltrating at inflammatory sites: a population of monocytes/macrophages with a cytotoxic phenotype

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Multiple populations of T lymphocytes are distinguished by the level of CD4 and CD8 coexpression and require individual consideration.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Increased CD4+/CD8+ double-positive T cells in chronic Chagasic patients

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Double positive CD4CD8 alphabeta T cells: a new tumor-reactive population in human melanomas

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Distinct CD4+ CD8+ double-positive T cells in the blood and liver of patients during chronic hepatitis B and C

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

In vitro induction of regulatory CD4+CD8α+ T cells by TGF-β, IL-7 and IFN-γ.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Peripheral CD4CD8 double positive T cells with a distinct helper cytokine profile are increased in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

The presence of CD8+ invariant NKT cells in mice

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Isolation of human CD4/CD8 double-positive, graft-versus-host disease-protective, minor histocompatibility antigen-specific regulatory T cells and of a novel HLA-DR7-restricted HY-specific CD4 clone

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Rat peripheral CD4+CD8+ T lymphocytes are partially immunocompetent thymus-derived cells that undergo post-thymic maturation to become functionally mature CD4+ T lymphocytes.

1 reference

https://api.crossref.org/works/10.1189%2FJLB.1RU0814-382

7 January 2021

Identifiers

DOI

10.1189/JLB.1RU0814-382

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25360000%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017