Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery (Q26823541)

Schneider C

2

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Suk JS

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Cone R

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Hanes J

5

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language of work or name

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24 July 2012

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24

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page(s)

3887-94

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issue

28

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Micro- and macrorheology of mucus

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Mucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructure

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Biodegradable mucus-penetrating nanoparticles composed of diblock copolymers of polyethylene glycol and poly(lactic-co-glycolic acid)

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Mucus-penetrating nanoparticles for vaginal drug delivery protect against herpes simplex virus

28 September 2017

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A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles

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N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.

28 September 2017

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Drug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus

28 September 2017

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Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients

28 September 2017

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Rapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteine

28 September 2017

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Biodegradable nanoparticles composed entirely of safe materials that rapidly penetrate human mucus

28 September 2017

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Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses

28 September 2017

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Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.

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Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina

28 September 2017

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Human immunodeficiency virus type 1 is trapped by acidic but not by neutralized human cervicovaginal mucus

28 September 2017

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Long-term transgene expression in the central nervous system using DNA nanoparticles

28 September 2017

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Mucins, mucus, and sputum

28 September 2017

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The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.

28 September 2017

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Extracellular barriers in respiratory gene therapy.

28 September 2017

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Gene transfer to the lung: lessons learned from more than 2 decades of CF gene therapy

28 September 2017

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Barrier properties of mucus

28 September 2017

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Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

28 September 2017

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Nanoparticles as protein and gene carriers to mucosal surfaces.

28 September 2017

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Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier

28 September 2017

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MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

28 September 2017

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Rapid transport of large polymeric nanoparticles in fresh undiluted human mucus

28 September 2017

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Evidence for airway surface dehydration as the initiating event in CF airway disease

28 September 2017

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Real-time multiple-particle tracking: applications to drug and gene delivery

28 September 2017

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Why consider vaginal drug administration?

28 September 2017

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Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis.

28 September 2017

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Polyanhydrides: an overview.

28 September 2017

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Comparative uptake studies of bioadhesive and non-bioadhesive nanoparticles in human intestinal cell lines and rats: the effect of mucus on particle adsorption and transport.

28 September 2017

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Diffusion of macromolecules and virus-like particles in human cervical mucus

28 September 2017

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Surface modifications and molecular imprinting of polymers in medical and pharmaceutical applications

28 September 2017

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Molecular aspects of muco- and bioadhesion: tethered structures and site-specific surfaces

28 September 2017

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Antibody diffusion in human cervical mucus

28 September 2017

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Novel approaches to vaginal delivery and safety of microbicides: biopharmaceuticals, nanoparticles, and vaccines

28 September 2017

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Transfection of airway epithelium by stable PEGylated poly-L-lysine DNA nanoparticles in vivo

31 May 2018

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Variances in mucus architecture as a cause of cervical factor infertility.

31 May 2018

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Human cervical mucus and its interaction with sperm: a fine-structural view

31 May 2018

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Transport of metal oxide nanoparticles and single-walled carbon nanotubes in human mucus

31 May 2018

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Pegylated GL67 lipoplexes retain their gene transfection activity after exposure to components of CF mucus

21 January 2018

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Enhanced viscoelasticity of human cystic fibrotic sputum correlates with increasing microheterogeneity in particle transport.

21 January 2018

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Ultrastructure of the human periovulatory cervical mucus

21 January 2018

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Pluronic-based cationic block copolymer for forming pDNA polyplexes with enhanced cellular uptake and improved transfection efficiency

21 January 2018

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Uptake and release of budesonide from mucoadhesive, pH-sensitive copolymers and their application to nasal delivery

21 January 2018

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12 December 2020

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12 December 2020

Human cervical mucus during the menstrual cycle and pregnancy in normal and pathological conditions

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12 December 2020

Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres

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12 December 2020