Development of asparaginase Erwinia chrysanthemi for the treatment of acute lymphoblastic leukemia (Q26825970)

Barbara L. Asselin

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2

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Paul V. Plourde

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3

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Tim Corn

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4

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language of work or name

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November 2014

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Annals of the New York Academy of Sciences

published in

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volume

1329

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page(s)

81-92

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Modern therapy of acute lymphoblastic leukemia

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Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. I. Properties of the L-asparaginase of guinea pig serum in relation to those of the antilymphoma substance

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Evidence that the L-asparaginase of guinea pig serum is responsible for its antilymphoma effects. II. Lymphoma 6C3HED cells cultured in a medium devoid of L-asparagine lose their susceptibility to the effects of guinea pig serum in vivo

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Suppression of murine leukemias by L-asparaginase. Incidence of sensitivity among leukemias of various types: comparative inhibitory activities of guinea pig serum L-asparaginase and Escherichia coli L-asparaginase

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Two L-asparaginases from E. coli and their action against tumors

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L-Asparaginase in Treatment of Acute Leukaemia and Lymphosarcoma

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Toxic and antineoplastic effects of L-asparaginase. Study of mice with lymphoma and normal monkeys and report on a child with leukemia.

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E. coli L-asparaginase in the treatment of leukemia and solid tumors in 131 children

21 January 2018

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Toxicity of E. coli L-asparaginase in man

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Immunological responses to L-asparaginase

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Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01.

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Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber ALL Consortium Protocol 87-01.

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Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organisation for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial

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A randomized comparison of native Escherichia coli asparaginase and polyethylene glycol conjugated asparaginase for treatment of children with newly diagnosed standard-risk acute lymphoblastic leukemia: a Children's Cancer Group study

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Monitoring of asparaginase activity and asparagine levels in children on different asparaginase preparations.

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L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase

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Pharmacokinetics of native Escherichia coli asparaginase (Asparaginase medac) and hypersensitivity reactions in ALL-BFM 95 reinduction treatment.

21 January 2018

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Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia

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Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients

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Comparison of native E. coli and PEG asparaginase pharmacokinetics and pharmacodynamics in pediatric acute lymphoblastic leukemia

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The anti-asparagines antibodies correlate with L-asparagines activity and may affect clinical outcome of childhood acute lymphoblastic leukemia

21 January 2018

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Asparaginase antibody and asparaginase activity in children with higher-risk acute lymphoblastic leukemia: Children's Cancer Group Study CCG-1961.

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Erwinia asparaginase achieves therapeutic activity after pegaspargase allergy: a report from the Children's Oncology Group

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Safety profile of asparaginase Erwinia chrysanthemi in a large compassionate-use trial.

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Postinduction dexamethasone and individualized dosing of Escherichia Coli L-asparaginase each improve outcome of children and adolescents with newly diagnosed acute lymphoblastic leukemia: results from a randomized study--Dana-Farber Cancer Institut

21 January 2018

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A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia

21 January 2018

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Early postinduction intensification therapy improves survival for children and adolescents with high-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group

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Acute lymphoblastic leukaemia

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Long-term results of a randomized trial on extended use of high dose L-asparaginase for standard risk childhood acute lymphoblastic leukemia

21 January 2018

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Evidence that the L-Asparaginase Activity of Guinea Pig Serum is responsible for its Antilymphoma Effects

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7 January 2021

L-asparaginase therapy in children with advanced leukemia. The Southwest Cancer Chemotherapy Study Group

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Erwinia carotovora asparaginase in patients with prior anaphylaxis to asparaginase from E. coli

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7 January 2021

Therapy with Erwinia L-asparaginase in children with acute leukemia after anaphylaxis to E. coli L-asparaginase

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7 January 2021

Comparison of anaphylactic reactions to asparaginase derived from Escherichia coli and from Erwinia cultures

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7 January 2021

Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia

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7 January 2021

The cross-reactivity of anti-asparaginase antibodies against different L-asparaginase preparations

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7 January 2021

TUMOR INHIBITORY EFFECT OF L-ASPARAGINASE FROM ESCHERICHIA COLI

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7 January 2021

Prognostic value of minimal residual disease in relapsed childhood acute lymphoblastic leukaemia

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7 January 2021

A new L-asparaginase with antitumour activity?

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7 January 2021

Two L-asparaginases from Escherichia coli B. Their separation, purification, and antitumor activity

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7 January 2021

L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure

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7 January 2021

Flow cytometric follow-up of minimal residual disease in bone marrow gives prognostic information in children with acute lymphoblastic leukemia.

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7 January 2021

Evaluation of immunologic crossreaction of antiasparaginase antibodies in acute lymphoblastic leukemia (ALL) and lymphoma patients

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7 January 2021

Dose reduction of asparaginase under pharmacokinetic and pharmacodynamic control during induction therapy in children with acute lymphoblastic leukaemia

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7 January 2021

Pharmacokinetic dose adjustment of Erwinia asparaginase in protocol II of the paediatric ALL/NHL-BFM treatment protocols

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7 January 2021

Pegylated asparaginase (Oncaspar) in children with ALL: drug monitoring in reinduction according to the ALL/NHL-BFM 95 protocols

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7 January 2021

Asparaginase and Glutaminase Activities of Bacteria

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7 January 2021

Minimal residual disease in acute lymphoblastic leukemia

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7 January 2021

Prognostic importance of measuring early clearance of leukemic cells by flow cytometry in childhood acute lymphoblastic leukemia

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7 January 2021

Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials

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7 January 2021

Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and an excellent outcome

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7 January 2021

Comparative pharmacokinetic studies of three asparaginase preparations

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7 January 2021

Treatment of childhood acute lymphoblastic leukemia: results of Dana-Farber Cancer Institute/Children's Hospital Acute Lymphoblastic Leukemia Consortium Protocol 85-01.

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7 January 2021

Hypersensitivity or development of antibodies to asparaginase does not impact treatment outcome of childhood acute lymphoblastic leukemia

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7 January 2021