Prospects for gene transfer for clinical heart failure (Q26830145)

M H Gao

series ordinal

2

1 reference

H Kirk Hammond

series ordinal

3

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language of work or name

1 reference

June 2012

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19

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issue

6

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page(s)

606-12

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Executive Summary: Heart Disease and Stroke Statistics--2012 Update: A Report From the American Heart Association

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1 reference

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Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure

7 April 2017

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Gene therapy targets in heart failure: the path to translation

7 April 2017

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Cardiac-targeted delivery of regulatory RNA molecules and genes for the treatment of heart failure

7 April 2017

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Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model

7 April 2017

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S100A1 gene therapy for heart failure: a novel strategy on the verge of clinical trials

7 April 2017

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

7 April 2017

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AAV6.βARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model

7 April 2017

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Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

28 September 2017

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Reduced collagen deposition in infarcted myocardium facilitates induced pluripotent stem cell engraftment and angiomyogenesis for improvement of left ventricular function

28 September 2017

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Improved function of the failing rat heart by regulated expression of insulin-like growth factor I via intramuscular gene transfer

28 September 2017

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Treatment of pulmonary arterial hypertension with targeted therapies

28 September 2017

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Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Activated expression of cardiac adenylyl cyclase 6 reduces dilation and dysfunction of the pressure-overloaded heart

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Beneficial effects of adenylyl cyclase type 6 (AC6) expression persist using a catalytically inactive AC6 mutant

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Cardiac gene therapy with SERCA2a: from bench to bedside

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Activation of cardiac adenylyl cyclase expression increases function of the failing ischemic heart in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Gene therapy: targeting the myocardium

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Gene therapy progress and prospects: therapeutic angiogenesis for ischemic cardiovascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Myocardial gene transfer and long-term expression following intracoronary delivery of adeno-associated virus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Adenylyl cyclase type VI gene transfer reduces phospholamban expression in cardiac myocytes via activating transcription factor 3.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Correlation between serum doxycycline concentrations and serologic evolution in patients with Coxiella burnetii endocarditis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Angiogenic gene therapy for heart disease: a review of animal studies and clinical trials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Increased expression of adenylylcyclase type VI proportionately increases beta-adrenergic receptor-stimulated production of cAMP in neonatal rat cardiac myocytes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Transgenic Galphaq overexpression induces cardiac contractile failure in mice

28 September 2017

1 reference

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Sympathetic Nervous System and Aging in Man

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Effect of oral milrinone on mortality in severe chronic heart failure. The PROMISE Study Research Group

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

beta(1)-Adrenergic receptor vs adenylyl cyclase 6 expression in cardiac myocytes: differences in transgene localization and intracellular signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Activation of PH-domain leucine-rich protein phosphatase 2 (PHLPP2) by agonist stimulation in cardiac myocytes expressing adenylyl cyclase type 6.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Adenylyl cyclase type VI increases Akt activity and phospholamban phosphorylation in cardiac myocytes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to beta-adrenergic stimulation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Direct in vivo gene transfer into porcine myocardium using replication-deficient adenoviral vectors

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3555515

Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals

31 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac performance in a pacing model of congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Intracoronary administration of AdvFGF-5 (fibroblast growth factor-5) ameliorates left ventricular dysfunction and prevents myocyte loss in swine with developing collaterals and ischemic cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Multiply attenuated, self-inactivating lentiviral vectors efficiently deliver and express genes for extended periods of time in adult rat cardiomyocytes in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Indirect intracoronary delivery of adenovirus encoding adenylyl cyclase increases left ventricular contractile function in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Controlled expression of cardiac-directed adenylylcyclase type VI provides increased contractile function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Adenylyl cyclase increases survival in cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Adenylylcyclase gene transfer increases function of the failing heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Cardiac-directed expression of adenylyl cyclase and heart rate regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Adenylyl cyclase type VI corrects cardiac sarcoplasmic reticulum calcium uptake defects in cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Cardiac-directed expression of adenylyl cyclase reverses electrical remodeling in cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Increased cardiac adenylyl cyclase expression is associated with increased survival after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Cardiac-directed expression of adenylyl cyclase VI facilitates atrioventricular nodal conduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Trends in Heart Failure Incidence and Survival in a Community-Based Population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGT.2012.36

Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity

21 January 2018

1 reference

12 December 2020

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1 reference

12 December 2020

Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice

1 reference

12 December 2020

Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure

1 reference

12 December 2020

Reversal of cardiac dysfunction after long-term expression of SERCA2a by gene transfer in a pre-clinical model of heart failure

1 reference

12 December 2020

Dimensions Publication ID

Identifiers

DOI

10.1038/GT.2012.36

0 references

1037600534

0 references

Fatcat ID

release_lomt7svtffacra3rp7clxb2kz4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lomt7svtffacra3rp7clxb2kz4

24 November 2022