Manganese neurotoxicity and the role of reactive oxygen species (Q26853665)

author name string

Ebany J. Martinez-Finley

series ordinal

1

1 reference

Claire E. Gavin

series ordinal

2

1 reference

Thomas E. Gunter

series ordinal

4

1 reference

language of work or name

1 reference

September 2013

1 reference

Free Radical Biology and Medicine

published in

1 reference

volume

62

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page(s)

65-75

1 reference

Mild steel welding fume causes manganese accumulation and subtle neuroinflammatory changes but not overt neuronal damage in discrete brain regions of rats after short-term inhalation exposure

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28 September 2017

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31 May 2018

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Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions

31 May 2018

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Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.

31 May 2018

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Oxidative stress involves in astrocytic alterations induced by manganese

31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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31 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Catecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganous ion as a spin label in studies of mitochondrial uptake of manganese

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

The role of Ca 2+ in control of malic enzyme activity in bovine adrenal cortex mitochondria.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Chronic manganese poisoning: a neuropathological study with determination of manganese distribution in the brain

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese poisoning and the attack of trivalent manganese upon catecholamines

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Selective vulnerability of glutathione metabolism and cellular defense mechanisms in rat striatum to manganese.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Evolution and regulation of the gene encoding superoxide dismutase from the archaebacterium Halobacterium cutirubrum

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Release of mitochondrial matrix proteins through a Ca2+-requiring, cyclosporin-sensitive pathway

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese transport across the blood-brain barrier: relationship to iron homeostasis.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Phenylarsine oxide induces the cyclosporin A-sensitive membrane permeability transition in rat liver mitochondria

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Mn2+ sequestration by mitochondria and inhibition of oxidative phosphorylation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Increased GABA content in caudate nucleus of rats after chronic manganese chloride administration

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Mitochondria-targeted antioxidants as promising drugs for treatment of age-related brain diseases.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Effect of different C3-aryl substituents on the antioxidant activity of 4-hydroxycoumarin derivatives

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Molecular mechanism of manganese exposure-induced dopaminergic toxicity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI study.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Brain accumulation and toxicity of Mn(II) and Mn(III) exposures.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Tissue manganese concentrations in young male rhesus monkeys following subchronic manganese sulfate inhalation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Alzheimer type II astrocytic changes following sub-acute exposure to manganese and its prevention by antioxidant treatment

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Type 1 ryanodine receptor in cardiac mitochondria: transducer of excitation-metabolism coupling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

The influence of high iron diet on rat lung manganese absorption

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Ischemia, rather than reperfusion, inhibits respiration through cytochrome oxidase in the isolated, perfused rabbit heart: role of cardiolipin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Calcium-dependent mitochondrial superoxide modulates nuclear CREB phosphorylation in hippocampal neurons.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

EXPERIMENTAL MANGANESE ENCEPHALOPATHY IN MONKEYS. A PRELIMINARY REPORT

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Energy metabolism in astrocytes and neurons treated with manganese: relation among cell-specific energy failure, glucose metabolism, and intercellular trafficking using multinuclear NMR-spectroscopic analysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese distribution across the blood-brain barrier. I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Key role of succinate dehydrogenase in insulin-induced inactivation of protein tyrosine phosphatases.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese causes differential regulation of glutamate transporter (GLAST) taurine transporter and metallothionein in cultured rat astrocytes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Low cumulative manganese exposure affects striatal GABA but not dopamine

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Inhibition of the rat blood-brain barrier choline transporter by manganese chloride

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neurons

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Influence of particle solubility on the delivery of inhaled manganese to the rat brain: manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Calcium activation of heart mitochondrial oxidative phosphorylation: rapid kinetics of mVO2, NADH, AND light scattering

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Generation of superoxide in cardiomyocytes during ischemia before reperfusion.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese-induced developmental neurotoxicity in the CD rat: is oxidative damage a mechanism of action?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Effect of manganese on the concentration of amino acids in different regions of the rat brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Ca2+-stimulated mitochondrial reactive oxygen species generation and permeability transition are inhibited by dibucaine or Mg2+.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Blood manganese correlates with brain magnetic resonance imaging changes in patients with liver disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanisms.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Dopaminergic system activity and cellular defense mechanisms in the striatum and striatal synaptosomes of the rat subchronically exposed to manganese.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Ca(2+)-induced mitochondrial membrane permeabilization: role of coenzyme Q redox state.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Alterations in brain dopamine and GABA following inorganic or organic manganese administration.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

A comparison of the effects of different divalent cations on a number of mitochondrial reactions linked to ion translocation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3713115

Nmr spectroscopic analysis of regional brain energy metabolism in manganese neurotoxicity

28 November 2018

1 reference

12 December 2020

The clearance of manganese chloride in the primate

1 reference

12 December 2020

Manganese-induced reactive oxygen species: comparison between Mn+2 and Mn+3

1 reference

12 December 2020

Role of liver in regulating distribution and excretion of manganese

1 reference

12 December 2020

Mitochondrial damage induced by conditions of oxidative stress

1 reference

12 December 2020

Pharmacokinetics of inhaled manganese phosphate in male Sprague-Dawley rats following subacute (14-day) exposure

1 reference

12 December 2020

Manganese-induced rat pheochromocytoma (PC12) cell death is independent of caspase activation

1 reference

12 December 2020

The effect of manganese inhalation on basal ganglia dopamine concentrations in rhesus monkey

1 reference

12 December 2020

Manganese ions inhibit acetylcholine receptor synthesis in cultured mouse soleus muscles

1 reference

12 December 2020

Manganese balance studies in infants after operations on the heart

1 reference

12 December 2020

Manganese absorption and retention by young women is associated with serum ferritin concentration

1 reference

12 December 2020

Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes

1 reference

12 December 2020

Influence of the route of administration and the chemical form (MnCl 2 , MnO 2 ) on the absorption and cerebral distribution of manganese in rats

1 reference

12 December 2020

Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria

1 reference

12 December 2020

On the mechanism of the Mn3(+)-induced neurotoxicity of dopamine:prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase

1 reference

12 December 2020

Biliary manganese excretion in conscious rats is affected by acute and chronic manganese intake but not by dietary fat

1 reference

12 December 2020

Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss

1 reference

12 December 2020

Reactivity of ubiquinone and ubiquinol with superoxide and the hydroperoxyl radical: implications for in vivo antioxidant activity

1 reference

12 December 2020

Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes

1 reference

12 December 2020

The respiratory chain and oxidative phosphorylation

1 reference

12 December 2020

Toward an understanding of the role of glutamate in experimental parkinsonism: agonist-sensitive sites in the basal ganglia

1 reference

12 December 2020

Some effects of Ca2+, Mg2+ , and Mn2+ on the ultrastructure, light-scattering properties, and malic enzyme activity of adrenal cortex mitochondria

1 reference

12 December 2020

Superoxide radical as electron donor for oxidative phosphorylation of ADP

1 reference

12 December 2020

High dietary manganese lowers heart magnesium in pigs fed a low-magnesium diet

1 reference

12 December 2020

Alteration of cerebral neurotransmitter receptor function by exposure of rats to manganese

1 reference

12 December 2020

Chronic manganese poisoning Clearance of tissue manganese concentrations with persistence of the neurological picture

1 reference

12 December 2020

Manganese transport through human erythrocyte membranes. An EPR study

1 reference

12 December 2020

Direct interorganellar transfer of iron from endosome to mitochondrion

1 reference

12 December 2020

The mitochondrial ryanodine receptor in rat heart: a pharmaco-kinetic profile

1 reference

12 December 2020

Brain Regional Distribution of Glutamic Acid Decarboxylase, Choline Acetyltransferase, and Acetylcholinesterase in the Rat: Effects of Chronic Manganese Chloride Administration after Two Years

1 reference

12 December 2020

Enhancing effect of manganese on L-DOPA-induced apoptosis in PC12 cells: role of oxidative stress

1 reference

12 December 2020

Biological half-lives of zinc and manganese in rat brain

1 reference

12 December 2020

Dependence of manganese turnover on intake

1 reference

12 December 2020

Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism

1 reference

12 December 2020

The activation of adrenal cortex mitochondrial malic enzyme by Ca2+ and Mg2+

1 reference

12 December 2020

Enhanced autoxidation of dopamine as a possible basis of manganese neurotoxicity

1 reference

12 December 2020

Manganese toxicity: free amino acids in the striatum and olfactory bulb of the mouse

1 reference

12 December 2020

Response of mitochondrial reactive oxygen species generation to steady-state oxygen tension: implications for hypoxic cell signaling

1 reference

12 December 2020