Optimal glycemic control in neurocritical care patients: a systematic review and meta-analysis (Q26858961)

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David A Zygun

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3

1 reference

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language of work or name

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22 October 2012

8 references

25 June 2019

23 July 2019

17 November 2019

18 November 2019

20 November 2019

27 October 2020

19 July 2022

8 references

25 June 2019

23 July 2019

17 November 2019

18 November 2019

20 November 2019

27 October 2020

19 July 2022

16

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5

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Creative Commons Attribution 2.0 Generic

copyright license

7 references

25 June 2019

23 July 2019

17 November 2019

18 November 2019

20 November 2019

27 October 2020

Insulin for glycaemic control in acute ischaemic stroke

19 July 2022

0 references

1 reference

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Quantifying heterogeneity in a meta-analysis

21 March 2017

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Assessing the quality of reports of randomized clinical trials: is blinding necessary?

21 March 2017

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Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials

21 March 2017

1 reference

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The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration

21 March 2017

1 reference

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Intensive insulin therapy and pentastarch resuscitation in severe sepsis

21 March 2017

1 reference

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Intensive insulin therapy in critically ill patients

21 March 2017

1 reference

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Intensive insulin therapy in brain injury: a meta-analysis.

7 April 2017

1 reference

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Relationship between hyperglycemia and outcome in children with severe traumatic brain injury.

28 September 2017

1 reference

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Intensive insulin therapy in hospitalized patients: a systematic review

28 September 2017

1 reference

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Mean glucose during ICU admission is related to mortality by a U-shaped curve in surgical and medical patients: a retrospective cohort study

28 September 2017

1 reference

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Intensive versus conventional insulin therapy in critically ill neurologic patients.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Treating hyperglycemia in neurocritical patients: benefits and perils.

28 September 2017

1 reference

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Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury

28 September 2017

1 reference

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Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis

28 September 2017

1 reference

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Glucose Regulation in Acute Stroke Patients (GRASP) trial: a randomized pilot trial

28 September 2017

1 reference

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Hyperglycemia and clinical outcome in aneurysmal subarachnoid hemorrhage: a meta-analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Derangements in blood glucose following initial resuscitation from in-hospital cardiac arrest: a report from the national registry of cardiopulmonary resuscitation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Effective glycemic control with aggressive hyperglycemia management is associated with improved outcome in aneurysmal subarachnoid hemorrhage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Persistent hyperglycemia in severe traumatic brain injury: an independent predictor of outcome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Admission hyperglycemia predicts a worse outcome in stroke patients treated with intravenous thrombolysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Benefits and risks of tight glucose control in critically ill adults: a meta-analysis

28 September 2017

1 reference

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28 September 2017

1 reference

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Impact of medical complications on outcome after subarachnoid hemorrhage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy in the medical ICU.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Effects of admission hyperglycemia on mortality and costs in acute ischemic stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Plasma glucose levels and outcome after aneurysmal subarachnoid hemorrhage

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

The association of hyperglycemia with cerebral edema in stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy in the neurocritical care setting is associated with poor clinical outcomes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy in severe traumatic brain injury: a randomized trial

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia and short-term outcome in patients with spontaneous intracerebral hemorrhage

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Glucose levels and outcome after subarachnoid hemorrhage

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Persistently low extracellular glucose correlates with poor outcome 6 months after human traumatic brain injury despite a lack of increased lactate: a microdialysis study

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia and neurological outcome in patients with head injury.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Efficacy and safety of intensive insulin therapy for critically ill neurologic patients: a meta-analysis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Association of serum glucose concentrations during acute hospitalization with hematoma expansion, perihematomal edema, and three month outcome among patients with intracerebral hemorrhage.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Emergency Department hyperglycemia as a predictor of early mortality and worse functional outcome after intracerebral hemorrhage.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hypoglycemia is associated with intensive care unit mortality.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Efficacy and safety of two 5 day insulin dosing regimens to achieve strict glycaemic control in patients with acute ischaemic stroke.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Glucose control and mortality in patients with severe traumatic brain injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study.

28 November 2018

1 reference

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Clinical impact of early hyperglycemia during acute phase of traumatic brain injury.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Inpatient hyperglycemia following aneurysmal subarachnoid hemorrhage: relation to cerebral metabolism and outcome.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive versus conventional glucose control in critically ill patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Safety and efficacy of intensive insulin therapy in critical neurosurgical patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy on infection rate, days in NICU, in-hospital mortality and neurological outcome in severe traumatic brain injury patients: a randomized controlled trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Pragmatic management of hyperglycaemia in acute ischaemic stroke: safety and feasibility of intensive intravenous insulin treatment

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive versus conventional insulin therapy: a randomized controlled trial in medical and surgical critically ill patients.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Impact of tight glycemic control on cerebral glucose metabolism after severe brain injury: a microdialysis study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Effects of admission glucose level on mortality after subarachnoid hemorrhage: a comparison between short-term and long-term mortality.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Dynamic of hyperglycemia as a predictor of stroke outcome in the ECASS-II trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy after severe traumatic brain injury: a randomized clinical trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia and cerebral glucose in aneurysmal subarachnoid hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Treatment of hyperglycemia in ischemic stroke (THIS): a randomized pilot trial

28 November 2018

1 reference

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Persistent perioperative hyperglycemia as an independent predictor of poor outcome after aneurysmal subarachnoid hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy versus conventional glycemic control in patients with acute neurological injury: a prospective controlled trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Strict versus moderate glucose control after resuscitation from ventricular fibrillation

28 November 2018

1 reference

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Influence of hyperglycemia on stroke mortality.

28 November 2018

1 reference

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The effect of intensive insulin therapy on infection rate, vasospasm, neurologic outcome, and mortality in neurointensive care unit after intracranial aneurysm clipping in patients with acute subarachnoid hemorrhage: a randomized prospective pilot t

28 November 2018

1 reference

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Glucose-potassium-insulin infusions in the management of post-stroke hyperglycaemia: the UK Glucose Insulin in Stroke Trial (GIST-UK).

28 November 2018

1 reference

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Hyperglycemia independently increases the risk of early death in acute spontaneous intracerebral hemorrhage.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia during ischemia rapidly accelerates brain damage in stroke patients treated with tPA.

28 November 2018

1 reference

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A randomised, controlled pilot study to investigate the potential benefit of intervention with insulin in hyperglycaemic acute ischaemic stroke patients.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia after SAH: predictors, associated complications, and impact on outcome

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia, excess weight, and history of hypertension as risk factors for poor outcome and cerebral infarction after aneurysmal subarachnoid hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Relationship between hyperglycemia and symptomatic vasospasm after subarachnoid hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Insulin therapy protects the central and peripheral nervous system of intensive care patients

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

The impact of hyperglycemia on patients with severe brain injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia and outcomes from pediatric traumatic brain injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

A multiple logistic regression analysis of in-hospital factors related to survival at six months in patients resuscitated from out-of-hospital ventricular fibrillation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

The influence of diabetes and hyperglycemia on clinical course after intracerebral hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Hyperglycemia exacerbates brain edema and perihematomal cell death after intracerebral hemorrhage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

In-hospital factors associated with improved outcome after out-of-hospital cardiac arrest. A comparison between four regions in Norway.

28 November 2018

1 reference

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Acute hyperglycemia adversely affects stroke outcome: a magnetic resonance imaging and spectroscopy study.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

The influence of hyperglycemia on neurological outcome in patients with severe head injury

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682305

Cerebral hyperglycolysis following severe traumatic brain injury in humans: a positron emission tomography study

28 November 2018

1 reference

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Intravenous insulin therapy in the maintenance of strict glycemic control in nondiabetic acute stroke patients with mild hyperglycemia

28 November 2018

1 reference

12 December 2020

Does blinding of readers affect the results of meta-analyses? University of Pennsylvania Meta-analysis Blinding Study Group

1 reference

12 December 2020

Clinical significance of admission hyperglycemia and factors related to it in patients with acute severe head injury

1 reference

12 December 2020

Glucose potassium insulin infusions in the treatment of acute stroke patients with mild to moderate hyperglycemia: the Glucose Insulin in Stroke Trial (GIST)

1 reference

12 December 2020

Persistent Hyperglycemia >155 mg/dL in Acute Ischemic Stroke Patients: How Well Are We Correcting It?

1 reference

12 December 2020

Randomized, controlled trial of insulin for acute poststroke hyperglycemia

1 reference

12 December 2020

Relation between brain interstitial and systemic glucose concentrations after subarachnoid hemorrhage

1 reference

12 December 2020