Mammalian O-mannosylation: unsolved questions of structure/function (Q26860991)

author name string

Stephanie H Stalnaker

series ordinal

1

1 reference

Crossref

Ryan Stuart

series ordinal

2

1 reference

Crossref

Lance Wells

series ordinal

3

1 reference

Crossref

language of work or name

1 reference

October 2011

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Current Opinion in Structural Biology

published in

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volume

21

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issue

5

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page(s)

603-9

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Demonstration of mammalian protein O-mannosyltransferase activity: coexpression of POMT1 and POMT2 required for enzymatic activity

cites work

1 reference

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Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome

21 March 2017

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Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I

21 March 2017

1 reference

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Muscular dystrophy and neuronal migration disorder caused by mutations in a glycosyltransferase, POMGnT1

21 March 2017

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Mutations in the fukutin-related protein gene (FKRP) cause a form of congenital muscular dystrophy with secondary laminin alpha2 deficiency and abnormal glycosylation of alpha-dystroglycan

21 March 2017

1 reference

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A stoichiometric complex of neurexins and dystroglycan in brain

21 March 2017

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Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1

21 March 2017

1 reference

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The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family

21 March 2017

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An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophy

21 March 2017

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Mutations in the human LARGE gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan

21 March 2017

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Worldwide distribution and broader clinical spectrum of muscle-eye-brain disease

21 March 2017

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LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE

21 March 2017

1 reference

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Localization and functional analysis of the LARGE family of glycosyltransferases: significance for muscular dystrophy

21 March 2017

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Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus

21 March 2017

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Dystroglycan-alpha, a dystrophin-associated glycoprotein, is a functional agrin receptor

21 March 2017

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Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix

21 March 2017

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Pikachurin, a dystroglycan ligand, is essential for photoreceptor ribbon synapse formation

21 March 2017

1 reference

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Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality

21 March 2017

1 reference

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21 March 2017

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Glycosylation defects: a new mechanism for muscular dystrophy?

21 March 2017

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Mutant glycosyltransferase and altered glycosylation of alpha-dystroglycan in the myodystrophy mouse

21 March 2017

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Dystrophin: the protein product of the Duchenne muscular dystrophy locus

21 March 2017

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Membrane organization of the dystrophin-glycoprotein complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Glycomic analyses of mouse models of congenital muscular dystrophy

7 April 2017

1 reference

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Genetic Defects in Muscular Dystrophy

28 September 2017

1 reference

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Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding.

28 September 2017

1 reference

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Mucin-type O-glycosylation--putting the pieces together.

28 September 2017

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Comprehensive classification of nucleotidyltransferase fold proteins: identification of novel families and their representatives in human

28 September 2017

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Adaptive regulation at the cell surface by N-glycosylation.

28 September 2017

1 reference

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Mutational and functional analysis of Large in a novel CHO glycosylation mutant

28 September 2017

1 reference

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Loss of alpha-dystroglycan laminin binding in epithelium-derived cancers is caused by silencing of LARGE.

28 September 2017

1 reference

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Muscular dystrophies due to glycosylation defects

28 September 2017

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Congenital muscular dystrophies involving the O-mannose pathway

28 September 2017

1 reference

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Regulation of mammalian protein O-mannosylation: preferential amino acid sequence for O-mannose modification

28 September 2017

1 reference

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Diagnosis and cell-based therapy for Duchenne muscular dystrophy in humans, mice, and zebrafish

28 September 2017

1 reference

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Dystroglycan: from biosynthesis to pathogenesis of human disease.

28 September 2017

1 reference

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Posttranslational modification of alpha-dystroglycan, the cellular receptor for arenaviruses, by the glycosyltransferase LARGE is critical for virus binding.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Mouse large can modify complex N- and mucin O-glycans on alpha-dystroglycan to induce laminin binding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Role of glycosylation in development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Defective glycosylation in congenital muscular dystrophies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

N-Acetylglucosaminyltransferase IX acts on the GlcNAc beta 1,2-Man alpha 1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Characterization of POMT2, a novel member of the PMT protein O-mannosyltransferase family specifically localized to the acrosome of mammalian spermatids

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Overexpression of the cytotoxic T cell GalNAc transferase in skeletal muscle inhibits muscular dystrophy in mdx mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Muscular dystrophy--reason for optimism?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

O-mannosyl glycans in mammals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Detection of O-mannosyl glycans in rabbit skeletal muscle alpha-dystroglycan

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Structures of sialylated O-linked oligosaccharides of bovine peripheral nerve alpha-dystroglycan. The role of a novel O-mannosyl-type oligosaccharide in the binding of alpha-dystroglycan with laminin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Novel mannitol-containing oligosaccharides obtained by mild alkaline borohydride treatment of a chondroitin sulfate proteoglycan from brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Structural analysis of sequences O-linked to mannose reveals a novel Lewis X structure in cranin (dystroglycan) purified from sheep brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Characterization of site-specific O-glycan structures within the mucin-like domain of alpha-dystroglycan from human skeletal muscle

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

LARGE can functionally bypass alpha-dystroglycan glycosylation defects in distinct congenital muscular dystrophies.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Mutations in the FKRP gene can cause muscle-eye-brain disease and Walker-Warburg syndrome.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

High prevalence of 2-mono- and 2,6-di-substituted manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Targeted disruption of exon 52 in the mouse dystrophin gene induced muscle degeneration similar to that observed in Duchenne muscular dystrophy.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Brain contains HNK-1 immunoreactive O-glycans of the sulfoglucuronyl lactosamine series that terminate in 2-linked or 2,6-linked hexose (mannose).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3356693

Mutations in the fukutin-related protein gene (FKRP) identify limb girdle muscular dystrophy 2I as a milder allelic variant of congenital muscular dystrophy MDC1C

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21945038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cloning and expression of a novel UDP-GlcNAc:α-d-mannoside β1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:α-3-d-mannoside β1,2-N-acetylglucosaminyltransferase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/21945038

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.SBI.2011.09.001

1 reference

1 reference

1 reference

PubMed publication ID

21945038

1 reference