Ca2+ regulation of ion transport in the Na+/Ca2+ exchanger (Q26864939)

language of work or name

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14 September 2012

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Journal of Biological Chemistry

published in

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volume

287

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issue

38

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page(s)

31641-9

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Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system

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Calx, a Na-Ca exchanger gene of Drosophila melanogaster

21 March 2017

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Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger

21 March 2017

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Structural Basis of the Ca2+ Inhibitory Mechanism of Drosophila Na+/Ca2+ Exchanger CALX and Its Modification by Alternative Splicing

21 March 2017

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Ca2+ regulation in the Na+/Ca2+ exchanger features a dual electrostatic switch mechanism

21 March 2017

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Structure of the Calx-beta domain of the integrin beta4 subunit: insights into function and cation-independent stability

21 March 2017

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Crystal structure of CBD2 from the Drosophila Na(+)/Ca(2+) exchanger: diversity of Ca(2+) regulation and its alternative splicing modification

21 March 2017

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Structure and Functional Analysis of a Ca2+ Sensor Mutant of the Na+/Ca2+ Exchanger

21 March 2017

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The second Ca2+-binding domain of the Na+ Ca2+ exchanger is essential for regulation: crystal structures and mutational analysis

21 March 2017

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Cardiac excitation-contraction coupling

21 March 2017

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The crystal structure of the primary Ca2+ sensor of the Na+/Ca2+ exchanger reveals a novel Ca2+ binding motif

21 March 2017

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The cation/Ca(2+) exchanger superfamily: phylogenetic analysis and structural implications

21 March 2017

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Synaptotagmin-syntaxin interaction: the C2 domain as a Ca2+-dependent electrostatic switch

21 March 2017

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Cloning of a third mammalian Na+-Ca2+ exchanger, NCX3

21 March 2017

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Cloning of the NCX2 isoform of the plasma membrane Na(+)-Ca2+ exchanger

21 March 2017

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Calcium signalling: dynamics, homeostasis and remodelling

21 March 2017

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Alternative strategies in arrhythmia therapy: evaluation of Na/Ca exchange as an anti-arrhythmic target

7 April 2017

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Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger

28 September 2017

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The plasma membrane Ca²+ ATPase and the plasma membrane sodium calcium exchanger cooperate in the regulation of cell calcium

28 September 2017

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Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers

28 September 2017

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Crystal structures of progressive Ca2+ binding states of the Ca2+ sensor Ca2+ binding domain 1 (CBD1) from the CALX Na+/Ca2+ exchanger reveal incremental conformational transitions

28 September 2017

1 reference

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Roles of two Ca2+-binding domains in regulation of the cardiac Na+-Ca2+ exchanger

28 September 2017

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Ionic regulation of the cardiac sodium-calcium exchanger

28 September 2017

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Na+/Ca2+ exchangers: three mammalian gene families control Ca2+ transport.

28 September 2017

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Structural basis for Ca2+ regulation in the Na+/Ca2+ exchanger

28 September 2017

1 reference

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How does salt retention raise blood pressure?

28 September 2017

1 reference

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Therapeutic potential of novel Na+-Ca2+ exchange inhibitors in attenuating ischemia-reperfusion injury

28 September 2017

1 reference

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Elemental analysis of proteins by microPIXE.

28 September 2017

1 reference

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Pharmacology of brain Na+/Ca2+ exchanger: from molecular biology to therapeutic perspectives.

28 September 2017

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Forefront of Na+/Ca2+ exchanger studies: molecular pharmacology of Na+/Ca2+ exchange inhibitors

28 September 2017

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Conformational changes of the Ca(2+) regulatory site of the Na(+)-Ca(2+) exchanger detected by FRET.

28 September 2017

1 reference

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Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger

28 September 2017

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Development and application of Na+/Ca2+ exchange inhibitors

28 September 2017

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Multiple transport modes of the cardiac Na+/Ca2+ exchanger.

28 September 2017

1 reference

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Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400.

28 September 2017

1 reference

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Calcium signaling: a tale for all seasons

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Helix packing of functionally important regions of the cardiac Na(+)-Ca(2+) exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Cell-substrate interactions during sea urchin gastrulation: migrating primary mesenchyme cells interact with and align extracellular matrix fibers that contain ECM3, a molecule with NG2-like and multiple calcium-binding domains

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Sodium-calcium exchange: a molecular perspective

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Ionic regulatory properties of brain and kidney splice variants of the NCX1 Na(+)-Ca(2+) exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Sodium/calcium exchange: its physiological implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Unique topology of the internal repeats in the cardiac Na+/Ca2+ exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Regulatory function of Na-Ca exchange in the heart: milestones and outlook

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Anomalous regulation of the Drosophila Na(+)-Ca2+ exchanger by Ca2+

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

A 35-kDa protein is the basic unit of the core from the 2 x 10(4)-kDa aggregation factor responsible for species-specific cell adhesion in the marine sponge Microciona prolifera

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Mutually exclusive and cassette exons underlie alternatively spliced isoforms of the Na/Ca exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Identification of the high affinity Ca(2+)-binding domain of the cardiac Na(+)-Ca2+ exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Molecular cloning and functional expression of the cardiac sarcolemmal Na(+)-Ca2+ exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Interaction of PIP(2) with the XIP region of the cardiac Na/Ca exchanger

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Structure-function analysis of CALX1.1, a Na+-Ca2+ exchanger from Drosophila. Mutagenesis of ionic regulatory sites.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Tissue specificity and alternative splicing of the Na+/Ca2+ exchanger isoforms NCX1, NCX2, and NCX3 in rat.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Mutation of amino acid residues in the putative transmembrane segments of the cardiac sarcolemmal Na+-Ca2+ exchanger

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Regulation of the cardiac Na(+)-Ca2+ exchanger by Ca2+. Mutational analysis of the Ca(2+)-binding domain

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Molecular operations of the sodium-calcium exchanger revealed by conformation currents.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Charge movement during Na+ translocation by native and cloned cardiac Na+/Ca2+ exchanger.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Calcium influx in internally dialyzed squid giant axons

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

Regulation and deregulation of cardiac Na(+)-Ca2+ exchange in giant excised sarcolemmal membrane patches

31 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

The molecular determinants of ionic regulatory differences between brain and kidney Na+/Ca2+ exchanger (NCX1) isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Cells expressing unique Na+/Ca2+ exchange (NCX1) splice variants exhibit different susceptibilities to Ca2+ overload.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

A new topological model of the cardiac sarcolemmal Na+-Ca2+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Cardiac Na-Ca exchange and pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Sodium-calcium exchange does not require allosteric calcium activation at high cytosolic sodium concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Cleavage of the plasma membrane Na+/Ca2+ exchanger in excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

The exchanger inhibitory peptide region-dependent inhibition of Na+/Ca2+ exchange by SN-6 [2-[4-(4-nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester], a novel benzyloxyphenyl derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.R112.353573

Tissue-specific expression of Na(+)-Ca2+ exchanger isoforms

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442498

A novel isothiourea derivative selectively inhibits the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1

28 November 2018

1 reference

12 December 2020

The Na+/Ca2+ exchanger NCX1 has oppositely oriented reentrant loop domains that contain conserved aspartic acids whose mutation alters its apparent Ca2+ affinity

1 reference

12 December 2020

Sodium-dependent uptake of calcium by crab nerve

1 reference

12 December 2020

Effects of pH on Na+-Ca2+ exchange in canine cardiac sarcolemmal vesicles

1 reference

12 December 2020

Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger

1 reference

12 December 2020

Identification and evolution of dual-topology membrane proteins

1 reference

12 December 2020

Ca2+ regulation in the Na+/Ca2+ exchanger involves two markedly different Ca2+ sensors

1 reference

12 December 2020

Interactions between Ca2+ binding domains of the Na+-Ca2+ exchanger and secondary regulation

1 reference

12 December 2020

The mechanism by which cytoplasmic protons inhibit the sodium-calcium exchanger in guinea-pig heart cells

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.R112.353573

0 references

1 reference

PubMed publication ID

22822067

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