Cancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis (Q26866144)

language of work or name

1 reference

29 August 2013

1 reference

1 reference

32

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issue

35

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page(s)

4057-63

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Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition

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Angiopoietin-like 4 protein elevates the prosurvival intracellular O2(-):H2O2 ratio and confers anoikis resistance to tumors

21 March 2017

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Matrix crosslinking forces tumor progression by enhancing integrin signaling

21 March 2017

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Contrasting actions of selective inhibitors of angiopoietin-1 and angiopoietin-2 on the normalization of tumor blood vessels

21 March 2017

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Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment

21 March 2017

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Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

21 March 2017

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

21 March 2017

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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 March 2017

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

21 March 2017

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Disruption of epithelial cell-matrix interactions induces apoptosis

21 March 2017

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 March 2017

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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

21 March 2017

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Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

21 March 2017

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Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

21 March 2017

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Emerging roles of angiopoietin-like 4 in human cancer

21 March 2017

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Anoikis resistance: an essential prerequisite for tumor metastasis

21 March 2017

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TGFbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4

21 March 2017

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Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

21 March 2017

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RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

21 March 2017

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The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

21 March 2017

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Purification and characterization of hypoxia-inducible factor 1

21 March 2017

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Genes that mediate breast cancer metastasis to lung

21 March 2017

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Accessories to the crime: functions of cells recruited to the tumor microenvironment

7 April 2017

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Basic and therapeutic aspects of angiogenesis

7 April 2017

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Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

7 April 2017

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Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

7 April 2017

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Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

7 April 2017

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

7 April 2017

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Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells

7 April 2017

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Hypoxia regulates CD44 and its variant isoforms through HIF-1α in triple negative breast cancer

28 September 2017

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CD24 is an effector of HIF-1-driven primary tumor growth and metastasis

28 September 2017

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Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

28 September 2017

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Adjuvant therapy in stage I carcinoma of the breast: the influence of multigene analyses and molecular phenotyping

28 September 2017

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Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia

28 September 2017

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Endothelial cell HIF-1α and HIF-2α differentially regulate metastatic success

28 September 2017

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Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis

28 September 2017

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Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation

28 September 2017

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HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs

28 September 2017

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Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin β1 signaling in human hepatocellular carcinoma

28 September 2017

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Multihistology, target-driven pilot trial of oral topotecan as an inhibitor of hypoxia-inducible factor-1α in advanced solid tumors

28 September 2017

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Antiangiogenic therapy: impact on invasion, disease progression, and metastasis.

28 September 2017

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Triple negative breast cancer: unmet medical needs

28 September 2017

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Expression of platelet-derived growth factor (PDGF)-B and PDGF-receptor β is associated with lymphatic metastasis in human gastric carcinoma

28 September 2017

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The role of the microenvironment in mammary gland development and cancer

28 September 2017

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Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

28 September 2017

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Lymphangiogenesis: Molecular mechanisms and future promise

28 September 2017

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Lymphangiogenesis and lymphatic metastasis in breast cancer

28 September 2017

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Pathways mediating VEGF-independent tumor angiogenesis

28 September 2017

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Hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients.

28 September 2017

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Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization

28 September 2017

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Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts

28 September 2017

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Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells

28 September 2017

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HIF-1alpha and HIF-2alpha have divergent roles in colon cancer.

28 September 2017

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Digoxin and other cardiac glycosides inhibit HIF-1alpha synthesis and block tumor growth

28 September 2017

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HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

28 September 2017

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Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer.

28 September 2017

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28 September 2017

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RACK1 competes with HSP90 for binding to HIF-1alpha and is required for O(2)-independent and HSP90 inhibitor-induced degradation of HIF-1alpha

28 September 2017

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Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha

28 September 2017

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The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression

28 September 2017

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PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis

28 September 2017

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HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression

28 September 2017

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Critical determinants of cancer metastasis: rationale for therapy

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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31 May 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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Overexpression of hypoxia-inducible factor HIF-1alpha predicts early relapse in breast cancer: retrospective study in a series of 745 patients

28 November 2018

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Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis

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Hypoxia inducible factor-1α correlates with VEGF-C expression and lymphangiogenesis in breast cancer

31 March 2020

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Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer

31 March 2020

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Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

31 March 2020

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis

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inferred from PubMed ID database lookup

12 December 2020

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Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2012.578

1 reference

Dimensions Publication ID

1049309005

0 references

1 reference

1 reference

PubMed publication ID

23222717

1 reference