Combining radiation and immunotherapy: a new systemic therapy for solid tumors? (Q26991721)

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31 May 2020

James P. Allison

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Daniel Gomez

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Chad Tang

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Xiaohong Wang

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Maria Angelica Cortez

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Erminia Massarelli

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David Hong

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Adi Diab

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Huiping Ye

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John Heymach

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Padmanee Sharma

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September 2014

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Cancer Immunology Research

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issue

9

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Nivolumab plus ipilimumab in advanced melanoma

31 May 2020

cites work

1 reference

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Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

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Combining radiotherapy and cancer immunotherapy: a paradigm shift

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Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

7 April 2017

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The blockade of immune checkpoints in cancer immunotherapy

7 April 2017

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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma

7 April 2017

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

7 April 2017

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Cancer immunotherapy: moving beyond current vaccines

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Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated

7 April 2017

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An extensive class of small RNAs in Caenorhabditis elegans

7 April 2017

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Dacarbazine-based chemotherapy for metastatic melanoma: thirty-year experience overview

7 April 2017

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Molecular basis of T cell inactivation by CTLA-4

7 April 2017

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Enhancement of antitumor immunity by CTLA-4 blockade

7 April 2017

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

7 April 2017

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Immunologic correlates of the abscopal effect in a patient with melanoma

7 April 2017

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Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

7 April 2017

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PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

7 April 2017

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Immunosuppressive networks in the tumour environment and their therapeutic relevance

7 April 2017

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c-Met expression is a marker of poor prognosis in patients with locally advanced head and neck squamous cell carcinoma treated with chemoradiation.

7 April 2017

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Irradiation and anti-PD-L1 treatment synergistically promote antitumor immunity in mice.

28 September 2017

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Exploring novel immune-related toxicities and endpoints with immune-checkpoint inhibitors in non-small cell lung cancer

28 September 2017

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Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing

28 September 2017

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Ipilimumab alone or in combination with radiotherapy in metastatic castration-resistant prostate cancer: results from an open-label, multicenter phase I/II study

28 September 2017

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The relevance of the TGF-β Paradox to EMT-MET programs

28 September 2017

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Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas

28 September 2017

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Radiation as an immunological adjuvant: current evidence on dose and fractionation.

28 September 2017

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Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects

28 September 2017

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Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study.

28 September 2017

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Induction of abscopal anti-tumor immunity and immunogenic tumor cell death by ionizing irradiation - implications for cancer therapies.

28 September 2017

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In situ vaccination against mycosis fungoides by intratumoral injection of a TLR9 agonist combined with radiation: a phase 1/2 study

28 September 2017

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Novel cancer immunotherapy agents with survival benefit: recent successes and next steps

28 September 2017

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In situ vaccination with a TLR9 agonist induces systemic lymphoma regression: a phase I/II study

28 September 2017

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Chemotherapy and radiotherapy: cryptic anticancer vaccines

28 September 2017

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Fractionated but not single-dose radiotherapy induces an immune-mediated abscopal effect when combined with anti-CTLA-4 antibody

28 September 2017

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Current systemic therapy for metastatic melanoma

28 September 2017

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Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment

28 September 2017

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CTLA-4 blockade increases IFNgamma-producing CD4+ICOShi cells to shift the ratio of effector to regulatory T cells in cancer patients

28 September 2017

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Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells.

28 September 2017

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Ipilimumab (anti-CTLA4 antibody) causes regression of metastatic renal cell cancer associated with enteritis and hypophysitis

28 September 2017

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Stereotactic body radiation therapy in multiple organ sites

28 September 2017

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The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

28 September 2017

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Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

28 September 2017

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Immune resistance orchestrated by the tumor microenvironment

28 September 2017

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Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy

28 September 2017

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Cytokines in cancer pathogenesis and cancer therapy

28 September 2017

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Chemokines and the tissue-specific migration of lymphocytes

28 September 2017

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Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

28 September 2017

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Radiation and the lung: a reevaluation of the mechanisms mediating pulmonary injury

28 September 2017

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An abscopal response to radiation and ipilimumab in a patient with metastatic non-small cell lung cancer.

28 September 2017

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A systemic complete response of metastatic melanoma to local radiation and immunotherapy.

31 May 2018

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Immunotherapy as a strategy for the treatment of non-small-cell lung cancer

31 May 2018

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Regulation of self-tolerance by CD80/CD86 interactions

31 May 2018

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Molecular pathways: next-generation immunotherapy--inhibiting programmed death-ligand 1 and programmed death-1.

31 May 2018

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Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial

28 November 2018

1 reference

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Radiotherapy increases the permissiveness of established mammary tumors to rejection by immunomodulatory antibodies.

28 November 2018

1 reference

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Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma

28 November 2018

1 reference

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Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition

28 November 2018

1 reference

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Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma

28 November 2018

1 reference

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Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer

28 November 2018

1 reference

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Radiation abscopal antitumor effect is mediated through p53

28 November 2018

1 reference

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Differential expression of PD-L1 and PD-L2, ligands for an inhibitory receptor PD-1, in the cells of lymphohematopoietic tissues.

28 November 2018

1 reference

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Radiation pneumonitis: a possible lymphocyte-mediated hypersensitivity reaction.

28 November 2018

1 reference

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Flt3L therapy following localized tumor irradiation generates long-term protective immune response in metastatic lung cancer: its implication in designing a vaccination strategy

28 November 2018

1 reference

12 December 2020

Initial Evaluation of Treatment-Related Pneumonitis in Advanced-Stage Non–Small-Cell Lung Cancer Patients Treated With Concurrent Chemotherapy and Intensity-Modulated Radiotherapy

1 reference

12 December 2020

Lymphopenia association with gross tumor volume and lung V5 and its effects on non-small cell lung cancer patient outcomes

1 reference

12 December 2020

Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group

1 reference

12 December 2020

Are the results of RTOG 0617 mysterious?

1 reference

12 December 2020

Ionising radiation induces changes associated with epithelial-mesenchymal transdifferentiation and increased cell motility of A549 lung epithelial cells

1 reference

12 December 2020

10.1158/2326-6066.CIR-14-0069

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31 May 2020

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31 May 2020

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