The RNA capping machinery as an anti-infective target (Q26995354)

Frédéric Picard-Jean

series ordinal

2

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Martin Bisaillon

series ordinal

3

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language of work or name

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2011

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Wiley interdisciplinary reviews. RNA

25 October 2010

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22 August 2022

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22 August 2022

2

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issue

2

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page(s)

184-92

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Viral and cellular mRNA capping: past and prospects

cites work

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Structure, mechanism, and evolution of the mRNA capping apparatus

21 January 2018

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What messenger RNA capping tells us about eukaryotic evolution.

21 January 2018

1 reference

Chlorella virus RNA triphosphatase. Mutational analysis and mechanism of inhibition by tripolyphosphate

21 January 2018

1 reference

Characterization of Schizosaccharomyces pombe RNA triphosphatase.

21 January 2018

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Energetics of RNA binding by the West Nile virus RNA triphosphatase.

21 January 2018

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Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase

21 January 2018

1 reference

Inhibition of a metal-dependent viral RNA triphosphatase by decavanadate

21 January 2018

1 reference

Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases

21 January 2018

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Kinetic and thermodynamic characterization of the RNA guanylyltransferase reaction

21 January 2018

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Mechanisms of action of ribavirin against distinct viruses

21 January 2018

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The broad spectrum antiviral nucleoside ribavirin as a substrate for a viral RNA capping enzyme.

21 January 2018

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Unconventional mechanism of mRNA capping by the RNA-dependent RNA polymerase of vesicular stomatitis virus.

21 January 2018

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Histidine-mediated RNA transfer to GDP for unique mRNA capping by vesicular stomatitis virus RNA polymerase

21 January 2018

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Inhibitors of respiratory syncytial virus replication target cotranscriptional mRNA guanylylation by viral RNA-dependent RNA polymerase

21 January 2018

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The flavivirus NS5 protein is a true RNA guanylyltransferase that catalyzes a two-step reaction to form the RNA cap structure

21 January 2018

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mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

21 January 2018

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Divergent subunit interactions among fungal mRNA 5'-capping machineries

21 January 2018

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Trypanosoma brucei RNA triphosphatase. Antiprotozoal drug target and guide to eukaryotic phylogeny

21 January 2018

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Trypanosome mRNAs have unusual "cap 4" structures acquired by addition of a spliced leader

21 January 2018

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In vitro capping in Trypanosoma cruzi identifies and shows specificity for the spliced leader RNA and U-RNAs

21 January 2018

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Effects of S-adenosylhomocysteine analogues on vaccinia viral messenger ribonucleic acid synthesis and methylation

21 January 2018

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Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymes

21 January 2018

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Differential effect of sinefungin and its analogs on the multiplication of three Leishmania species

21 January 2018

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Virtual screening and bioassay study of novel inhibitors for dengue virus mRNA cap (nucleoside-2'O)-methyltransferase

21 January 2018

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Flaviviral methyltransferase/RNA interaction: structural basis for enzyme inhibition

21 January 2018

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In vitro reconstitution of SARS-coronavirus mRNA cap methylation

21 January 2018

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Novel inhibitors of dengue virus methyltransferase: discovery by in vitro-driven virtual screening on a desktop computer grid

21 January 2018

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Mutational Analysis ofEncephalitozoon cuniculimRNA Cap (Guanine-N7) Methyltransferase, Structure of the Enzyme Bound to Sinefungin, and Evidence That Cap Methyltransferase Is the Target of Sinefungin's Antifungal Activity

21 January 2018

1 reference

Elucidation of the mechanism by which homocysteine potentiates the anti-vaccinia virus effects of the S-adenosylhomocysteine hydrolase inhibitor 9-(trans-2',trans-3'-dihydroxycyclopent-4'-enyl)-adenine.

21 January 2018

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12 December 2020

Antiviral treatment of cytomegalovirus infection and resistant strains

1 reference

12 December 2020

Inhibition of vaccinia RNA guanine 7-methyltransferase by compounds designed as multisubstrate adducts

1 reference

12 December 2020

Deciphering the molecular basis for nucleotide selection by the West Nile virus RNA helicase

1 reference

12 December 2020

The mRNA capping apparatus as drug target and guide to eukaryotic phylogeny

1 reference

12 December 2020

Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target

1 reference

12 December 2020

Antiviral potency of adenosine analogues: correlation with inhibition of S-adenosylhomocysteine hydrolase

1 reference

12 December 2020

Sinefungin, a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication

1 reference

12 December 2020