Pluripotent stem cells in regenerative medicine: challenges and recent progress (Q26999292)

language of work or name

1 reference

February 2014

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published in

Nature Reviews Genetics

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volume

15

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issue

2

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page(s)

82-92

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Molecular roadblocks for cellular reprogramming

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Human induced pluripotent stem cells free of vector and transgene sequences

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Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

7 April 2017

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Immunogenicity of induced pluripotent stem cells

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7 April 2017

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Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

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Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

7 April 2017

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Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts

7 April 2017

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A ROCK inhibitor permits survival of dissociated human embryonic stem cells

7 April 2017

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Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

7 April 2017

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Transplantation of embryonic dopamine neurons for severe Parkinson's disease

7 April 2017

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Enhancement of polysialic acid expression improves function of embryonic stem-derived dopamine neuron grafts in Parkinsonian mice

7 April 2017

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In vivo reprogramming of astrocytes to neuroblasts in the adult brain

28 September 2017

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Chemical approaches to stem cell biology and therapeutics

28 September 2017

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Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix

28 September 2017

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Human embryonic stem cells derived by somatic cell nuclear transfer.

28 September 2017

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Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells

28 September 2017

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28 September 2017

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Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies.

28 September 2017

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Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination

28 September 2017

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Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo

28 September 2017

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Cytosystems dynamics in self-organization of tissue architecture

28 September 2017

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Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells

28 September 2017

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Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

28 September 2017

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Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells.

28 September 2017

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Glial progenitor cell-based treatment and modeling of neurological disease

28 September 2017

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Induced pluripotent stem cells: the new patient?

28 September 2017

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Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest

28 September 2017

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A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development

28 September 2017

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Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment

28 September 2017

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Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors

28 September 2017

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Specification of midbrain dopamine neurons from primate pluripotent stem cells

28 September 2017

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Engineering bone tissue from human embryonic stem cells

28 September 2017

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Human ES- and iPS-derived myogenic progenitors restore DYSTROPHIN and improve contractility upon transplantation in dystrophic mice.

28 September 2017

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Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice.

28 September 2017

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28 September 2017

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Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells

28 September 2017

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Human embryonic stem cell-derived neurons adopt and regulate the activity of an established neural network

28 September 2017

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SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.

28 September 2017

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28 September 2017

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Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells

28 September 2017

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Cell fate plug and play: direct reprogramming and induced pluripotency

28 September 2017

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28 September 2017

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Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells.

28 September 2017

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Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells

28 September 2017

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Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent

28 September 2017

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Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

28 September 2017

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Genetic control of wayward pluripotent stem cells and their progeny after transplantation

28 September 2017

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A small molecule that directs differentiation of human ESCs into the pancreatic lineage.

28 September 2017

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Magnetic tagging of therapeutic cells for MRI

28 September 2017

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Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats.

28 September 2017

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Genetic modification of human embryonic stem cells for derivation of target cells

28 September 2017

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Combining growth factor and stem cell therapy for amyotrophic lateral sclerosis

28 September 2017

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Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson's disease

28 September 2017

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Derivation of engraftable skeletal myoblasts from human embryonic stem cells

28 September 2017

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Enhanced yield of neuroepithelial precursors and midbrain-like dopaminergic neurons from human embryonic stem cells using the bone morphogenic protein antagonist noggin.

28 September 2017

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Cellular magnetic resonance imaging: current status and future prospects

28 September 2017

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Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells.

28 September 2017

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Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation

28 September 2017

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Derivation of midbrain dopamine neurons from human embryonic stem cells

28 September 2017

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28 September 2017

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Biowire: a platform for maturation of human pluripotent stem cell-derived cardiomyocytes

28 September 2017

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Functional maturation of hPSC-derived forebrain interneurons requires an extended timeline and mimics human neural development.

28 September 2017

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In vivo reprogramming of circuit connectivity in postmitotic neocortical neurons.

31 May 2018

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Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

31 May 2018

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Efficient derivation of purified lung and thyroid progenitors from embryonic stem cells

31 May 2018

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Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

31 May 2018

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In vitro differentiation of transplantable neural precursors from human embryonic stem cells

31 May 2018

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A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease

21 January 2018

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21 January 2018

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How can human pluripotent stem cells help decipher and cure Huntington's disease?

21 January 2018

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Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

21 January 2018

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Geron gets green light for human trial of ES cell-derived product.

21 January 2018

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Human oligodendrocytes from embryonic stem cells: conserved SHH signaling networks and divergent FGF effects

21 January 2018

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Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells

21 January 2018

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Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.

21 January 2018

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Small-molecule inhibitors of bone morphogenic protein and activin/nodal signals promote highly efficient neural induction from human pluripotent stem cells.

21 January 2018

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Vascularized and functional human liver from an iPSC-derived organ bud transplant.

21 January 2018

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Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

21 January 2018

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Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells

21 January 2018

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Stem cells cruise to clinic

21 January 2018

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GMP scale-up and banking of pluripotent stem cells for cellular therapy applications

21 January 2018

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Deep brain stimulation in area LC controllably triggers auditory phantom percepts

21 January 2018

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Dopaminergic neurons for Parkinson's therapy

21 January 2018

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Three-dimensional biomaterials for the study of human pluripotent stem cells

31 March 2020

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Embryonic stem cell pioneer Geron exits field, cuts losses

31 March 2020

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Deep-brain stimulation for Parkinson's disease

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRG3563

1 reference

Dimensions Publication ID

2399665

1038807643

0 references

2399665

1 reference

1 reference

1 reference