Roles of glutamine synthetase inhibition in epilepsy (Q27000935)

1

1 reference

Kevin Behar

2

1 reference

Ronnie Dhaher

3

1 reference

Argyle V. Bumanglag

4

1 reference

Tih-Shih W. Lee

5

1 reference

language of work or name

1 reference

November 2012

1 reference

published in

Neurochemical Research

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volume

37

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issue

11

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page(s)

2339-50

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https://scigraph.springernature.com/pub.10.1007/s11064-012-0766-5

exact match

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cites work

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Epilepsy, regulation of brain energy metabolism and neurotransmission

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System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signaling by glutamate

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Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats

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28 September 2017

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New concepts in the mechanism of ammonia-induced astrocyte swelling

28 September 2017

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Excitatory synaptic transmission persists independently of the glutamate-glutamine cycle.

28 September 2017

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Astrocyte glycogen and brain energy metabolism

28 September 2017

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A glycogen phosphorylase inhibitor selectively enhances local rates of glucose utilization in brain during sensory stimulation of conscious rats: implications for glycogen turnover

28 September 2017

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Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1

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Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimer's disease

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Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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The expression of vesicular glutamate transporters defines two classes of excitatory synapse

28 September 2017

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28 September 2017

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In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during

28 September 2017

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Glutamine transport in brain mitochondria

28 September 2017

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28 September 2017

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Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

28 September 2017

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28 September 2017

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28 September 2017

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Identification of L-methionine-S-sulfoximine as the convulsant isomer of methionine sulfoximine

28 September 2017

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Biochemistry and physiology of brain ammonia

28 September 2017

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Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

28 September 2017

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Physiologic coupling of glial glycogen metabolism to neuronal activity in brain

28 September 2017

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Cerebral energy metabolism during experimental status epilepticus

28 September 2017

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Distribution of glutamine synthetase in the rat central nervous system

28 September 2017

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Glutamine synthetase in the developing rat retina: An immunohistochemical study

28 September 2017

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Glutamine Synthetase: Glial Localization in Brain

28 September 2017

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28 September 2017

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SAT1, A Glutamine Transporter, is Preferentially Expressed in GABAergic Neurons

31 May 2018

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Glutamine synthetase deficiency in murine astrocytes results in neonatal death

31 May 2018

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An astrocytic basis of epilepsy

31 May 2018

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Extracellular metabolites in the cortex and hippocampus of epileptic patients

31 May 2018

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31 May 2018

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Changes in the cellular distribution of glutamine synthetase in Alzheimer's disease

31 May 2018

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The localization of the brain-specific inorganic phosphate transporter suggests a specific presynaptic role in glutamatergic transmission.

31 May 2018

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Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease.

31 May 2018

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Glutamine synthetase immunoreactivity in the human hippocampus is lamina-specific.

31 May 2018

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Cortical GABA turnover during bicuculline seizures in rats.

31 May 2018

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Acute hyperammonemia in the young primate: physiologic and neuropathologic correlates.

31 May 2018

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Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.

31 May 2018

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Epilepsy and the temporal lobes. A clinical, electroencephalographic and neuropathological study of the brain in epilepsy, with particular reference to the temporal lobes.

31 May 2018

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Methionine sulfoximine seizures. 8. The dissociation of the convulsant and glutamine synthetase inhibitory effects

31 May 2018

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Pig brain glutaminase: purification and identification of different enzyme forms

31 May 2018

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Barbiturate-induced glycogen accumulation in brain. An electron microscopic study.

31 May 2018

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Glycogen and glycogen phosphorylase in the cerebral cortex of mice under the influence of methionine sulphoximine

31 May 2018

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Glial metabolism: alteration by potassium levels comparable to those during neural activity.

31 May 2018

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Cerebral metabolic changes during and following fluorothyl-induced seizures in ventilated rats.

31 May 2018

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Glycogen synthesis and immunocytochemical study of fructose-1,6-biphosphatase in methionine sulfoximine epileptogenic rodent brain.

31 May 2018

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The effect of diazepam on neonatal seizure: in vivo 31P and 1H NMR study

31 May 2018

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Role of glial cells for the basal and Ca2+-dependent K+-evoked release of transmitter amino acids investigated by microdialysis

31 May 2018

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Glutamate increases glycogen content and reduces glucose utilization in primary astrocyte culture.

31 May 2018

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Astroglial processes around identified glutamatergic synapses contain glutamine synthetase: evidence for transmitter degradation

31 May 2018

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Neuronal-glial metabolism under depolarizing conditions. A 13C-n.m.r. study

31 May 2018

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Sensory stimulation induces local cerebral glycogenolysis: demonstration by autoradiography

31 May 2018

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Comparative studies on glutamate metabolism in synpatic and non-synaptic rat brain mitochondria

31 May 2018

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Congenital glutamine deficiency with glutamine synthetase mutations

31 May 2018

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Increased expression of glutaminase and glutamine synthetase mRNA in the thalamus in schizophrenia

21 January 2018

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Loss of glutamine synthetase in the human epileptogenic hippocampus: possible mechanism for raised extracellular glutamate in mesial temporal lobe epilepsy

21 January 2018

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Reduced glutamine synthetase in hippocampal areas with neuron loss in temporal lobe epilepsy

21 January 2018

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Astrocytosis in wobbler mouse spinal cord involves a population of astrocytes which is glutamine synthetase-negative.

21 January 2018

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Astrocytic energy metabolism and glutamate formation--relevance for 13C-NMR spectroscopy and importance of cytosolic/mitochondrial trafficking.

21 January 2018

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Unchanged glutamine synthetase activity and increased NMDA receptor density in epileptic human neocortex: implications for the pathophysiology of epilepsy.

21 January 2018

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Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain.

21 January 2018

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N-acetyl-aspartate, total creatine, and myo-inositol in the epileptogenic human hippocampus

21 January 2018

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Glutamate-glutamine cycling in the epileptic human hippocampus

21 January 2018

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Regional differences in glutamine synthetase inhibition by L-methionine sulfoximine: a microdialysis study in the rabbit brain

21 January 2018

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Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors.

21 January 2018

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Alteration of Striatal Glutamate Release After Glutamine Synthetase Inhibition

21 January 2018

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Glutamate immunoreactivity in rat cerebral cortex is reversibly abolished by 6-diazo-5-oxo-L-norleucine (DON), an inhibitor of phosphate-activated glutaminase.

21 January 2018

1 reference

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Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats.

21 January 2018

1 reference

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Direct demonstration by [13C]NMR spectroscopy that glutamine from astrocytes is a precursor for GABA synthesis in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

White bread and epilepsy in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

In vivo and in vitro glycogenic effects of methionine sulfoximine are different in two inbred strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Glycogen, ammonia and related metabolities in the brain during seizures evoked by methionine sulphoximine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Postembedding immunogold labelling reveals subcellular localization and pathway-specific enrichment of phosphate activated glutaminase in rat cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Metabolic, circulatory, and structural alterations in the rat brain induced by sustained pentylenetetrazole seizures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

In vivo phosphorus nuclear magnetic resonance spectroscopy in status epilepticus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

High glycogen levels in the hippocampus of patients with epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Inhibition of glycogenolysis in astrocytes interrupts memory consolidation in young chickens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Glycogen is a preferred glutamate precursor during learning in 1-day-old chick: biochemical and behavioral evidence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Reciprocal changes in forebrain contents of glycogen and of glutamate/glutamine during early memory consolidation in the day-old chick

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11064-012-0766-5

Inhibition of glutamate/glutamine cycle in vivo results in decreased benzodiazepine binding and differentially regulated GABAergic subunit expression in the rat brain

21 January 2018

1 reference

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Isolation of glutamine synthetase and glutamotransferase from green peas.

28 November 2018

1 reference

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Brain glycogen decreases with increased periods of wakefulness: implications for homeostatic drive to sleep.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731630

Synergistic versus antagonistic actions of glutamate and glutathione: the role of excitotoxicity and oxidative stress in neuronal disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731630

Exogenous glutamate concentration regulates the metabolic fate of glutamate in astrocytes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731630

Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731630

Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures.

28 November 2018

1 reference

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Neural networks in human epilepsy: evidence of and implications for treatment

28 November 2018

1 reference

12 December 2020

Correlation between brain glycogen and convulsive state in mice submitted to methionine sulfoximine

1 reference

12 December 2020

The enzymatic synthesis of glutamine, a reaction utilizing adenosine triphosphate

1 reference

12 December 2020

GLUTAMINE SYNTHETASE. I. A COMPARATIVE STUDY OF ITS DISTRIBUTION IN ANIMALS AND ITS INHIBITION BY DL-ALLO-DELTA-HYDROXYLYSINE

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12 December 2020

Adenosinetriphosphate in Glutamine Synthesis

1 reference

12 December 2020

Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures

1 reference

12 December 2020

The syndrome of impending hepatic coma in patients with cirrhosis of the liver given certain nitrogenous substances

1 reference

12 December 2020

Kainic acid neurotoxicity toward hippocampal formation: dependence on specific excitatory pathways

1 reference

12 December 2020

Purification and immunocharacterization of human brain glutamine synthetase and its detection in cerebrospinal fluid and serum by a sandwich enzyme immunoassay

1 reference

12 December 2020

Methionine sulfoximine shows excitotoxic actions in rat cortical slices

1 reference

12 December 2020

Reversible toxic manifestations in patients with cirrhosis of the liver given cation-exchange resins

1 reference

12 December 2020

Glutamine synthetase is essential in early mouse embryogenesis

1 reference

12 December 2020

Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter

1 reference

12 December 2020

Natural course of glutamine synthetase deficiency in a 3 year old patient

1 reference

12 December 2020

Neuronal expression of glutamine synthetase in Alzheimer's disease indicates a profound impairment of metabolic interactions with astrocytes

1 reference

12 December 2020