Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review (Q27005619)

Marnie Duncan

series ordinal

2

1 reference

language of work or name

1 reference

February 2015

1 reference

British Journal of Pharmacology

published in

1 reference

volume

172

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issue

3

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page(s)

737-53

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Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

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Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects

21 March 2017

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Opposite effects of delta-9-tetrahydrocannabinol and cannabidiol on human brain function and psychopathology

21 March 2017

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The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration

21 March 2017

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The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin

21 March 2017

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The inheritance of chemical phenotype in Cannabis sativa L

21 March 2017

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The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors

21 March 2017

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Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

21 March 2017

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The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands

21 March 2017

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Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

21 March 2017

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An optimized approach to study endocannabinoid signaling: evidence against constitutive activity of rat brain adenosine A1 and cannabinoid CB1 receptors

21 March 2017

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International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂

21 March 2017

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Network pharmacology: the next paradigm in drug discovery

21 March 2017

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Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

21 March 2017

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Determination and characterization of a cannabinoid receptor in rat brain

21 March 2017

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The Concise Guide to PHARMACOLOGY 2013/14: enzymes.

7 April 2017

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28 September 2017

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The Concise Guide to PHARMACOLOGY 2013/14: ion channels

28 September 2017

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The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.

28 September 2017

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The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors

28 September 2017

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The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity

28 September 2017

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The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

28 September 2017

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Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment

28 September 2017

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Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures

28 September 2017

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Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

28 September 2017

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Cannabinoid potentiation of glycine receptors contributes to cannabis-induced analgesia.

28 September 2017

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Symptom-relieving and neuroprotective effects of the phytocannabinoid Δ⁹-THCV in animal models of Parkinson's disease

28 September 2017

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Subjective and physiological effects after controlled Sativex and oral THC administration

28 September 2017

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Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes

28 September 2017

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Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration

28 September 2017

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Diminished gray matter in the hippocampus of cannabis users: possible protective effects of cannabidiol

28 September 2017

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Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action

28 September 2017

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Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: naturalistic study: naturalistic study [corrected].

28 September 2017

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Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism.

28 September 2017

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The effects of Delta-tetrahydrocannabinol and cannabidiol alone and in combination on damage, inflammation and in vitro motility disturbances in rat colitis

28 September 2017

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The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

28 September 2017

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Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis

28 September 2017

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The endocannabinoid system, eating behavior and energy homeostasis: the end or a new beginning?

28 September 2017

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Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.

28 September 2017

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Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival

28 September 2017

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Cannabinoids Delta(9)-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-kappaB and interferon-beta/STAT proinflammatory pathways in BV-2 microglial cells

28 September 2017

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Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC:CBD extract and THC extract in patients with intractable cancer-related pain

28 September 2017

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Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

28 September 2017

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Evaluation of prevalent phytocannabinoids in the acetic acid model of visceral nociception

28 September 2017

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Cannabidiol reverses the reduction in social interaction produced by low dose Delta(9)-tetrahydrocannabinol in rats

28 September 2017

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Distinct effects of {delta}9-tetrahydrocannabinol and cannabidiol on neural activation during emotional processing

28 September 2017

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Cannabidiol: from an inactive cannabinoid to a drug with wide spectrum of action

28 September 2017

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Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids

28 September 2017

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TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons

28 September 2017

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Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

28 September 2017

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Targeting the endocannabinoid system: to enhance or reduce?

28 September 2017

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Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis

28 September 2017

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Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol

28 September 2017

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Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism

28 September 2017

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Cannabidiol--recent advances

28 September 2017

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Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences.

28 September 2017

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The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo

28 September 2017

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Comparison of orally administered cannabis extract and delta-9-tetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the C

28 September 2017

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The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids

28 September 2017

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A tale of two cannabinoids: the therapeutic rationale for combining tetrahydrocannabinol and cannabidiol

28 September 2017

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Neurophysiological and subjective profile of marijuana with varying concentrations of cannabinoids.

28 September 2017

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Clinical endocannabinoid deficiency (CECD): can this concept explain therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?

28 September 2017

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Effect of Delta-9-tetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults

28 September 2017

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Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis (CAMS study): multicentre randomised placebo-controlled trial

28 September 2017

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A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms

28 September 2017

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Use of coefficient of variation in assessing variability of quantitative assays

28 September 2017

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Metabolism of the endocannabinoids, 2-arachidonylglycerol and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters and ethanolamides

28 September 2017

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28 September 2017

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Synergy and other interactions in phytomedicines.

28 September 2017

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Side effects of pharmaceuticals not elicited by comparable herbal medicines: the case of tetrahydrocannabinol and marijuana

28 September 2017

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Complex pharmacology of natural cannabinoids: evidence for partial agonist activity of delta9-tetrahydrocannabinol and antagonist activity of cannabidiol on rat brain cannabinoid receptors

28 September 2017

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Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase

28 September 2017

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A Critical Review of the Safety and Antiemetic Efficacy of Delta-9-Tetrahydrocannabinol

28 September 2017

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Attenuation of inducible nitric oxide synthase gene expression by delta 9-tetrahydrocannabinol is mediated through the inhibition of nuclear factor- kappa B/Rel activation

28 September 2017

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Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ(9) -tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats

28 September 2017

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Anandamide serves two masters in the brain

31 May 2018

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Pre-synaptic adenosine A2A receptors control cannabinoid CB1 receptor-mediated inhibition of striatal glutamatergic neurotransmission.

31 May 2018

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A behavioural comparison of acute and chronic Delta9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice

31 May 2018

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Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice

31 May 2018

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Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain: mechanisms involved

31 May 2018

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Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system

31 May 2018

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Differential effects of THC- or CBD-rich cannabis extracts on working memory in rats

31 May 2018

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Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation

31 May 2018

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Discriminative Stimulus Properties of Δ9-Tetrahydrocannabinol: Mechanistic Studies

31 May 2018

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Regulation of adenylate cyclase by cannabinoid drugs. Insights based on thermodynamic studies

31 May 2018

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Delta9-THC as a discriminative cue in pigeons: effects of delta8-THC, CBD, and CBN.

31 May 2018

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(-)-Delta9-tetrahydrocannabinol antagonizes the peripheral cannabinoid receptor-mediated inhibition of adenylyl cyclase

31 May 2018

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Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids

21 January 2018

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Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats

21 January 2018

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The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic-ischemic brain damage in mice is mediated by CB(2) and adenosine receptors.

21 January 2018

1 reference

Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action.

21 January 2018

1 reference

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

21 January 2018

1 reference

The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors.

21 January 2018

1 reference

Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptor activation in mice

21 January 2018

1 reference

Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats

21 January 2018

1 reference

Different effects of nabilone and cannabidiol on binocular depth inversion in Man.

21 January 2018

1 reference

Allosteric Modulation of G Protein–Coupled Receptors

21 January 2018

1 reference

Cannabis and Cannabis Extracts

21 January 2018

1 reference

21 January 2018

1 reference

Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 'N of 1' studies

21 January 2018

1 reference

Effect of chronic exposure to rimonabant and phytocannabinoids on anxiety-like behavior and saccharin palatability.

21 January 2018

1 reference

Psychomotor performance in relation to acute oral administration of Delta9-tetrahydrocannabinol and standardized cannabis extract in healthy human subjects

21 January 2018

1 reference

Neuroprotective effects of phytocannabinoid-based medicines in experimental models of Huntington's disease.

21 January 2018

1 reference

Cannabis with high cannabidiol content is associated with fewer psychotic experiences.

21 January 2018

1 reference

The interaction of cannabinoids and opioids on pentylenetetrazole-induced seizure threshold in mice

21 January 2018

1 reference

A phase I study to assess the single and multiple dose pharmacokinetics of THC/CBD oromucosal spray.

21 January 2018

1 reference

Interactions between THC and cannabidiol in mouse models of cannabinoid activity

21 January 2018

1 reference

The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy

21 January 2018

1 reference

Medicinal cannabis: is delta9-tetrahydrocannabinol necessary for all its effects?

21 January 2018

1 reference

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsiv

21 January 2018

1 reference

Characteristics of the stimulus produced by the mixture of cannabidiol with delta 9-tetrahydrocannabinol

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4301686

Preliminary Experiments on the Chemistry and Pharmacology of Cannabis

28 November 2018

1 reference

Cannabidiol and cannabinol in man

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25257544