The efficacy of edaravone (radicut), a free radical scavenger, for cardiovascular disease (Q27015129)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

27 October 2022

The efficacy of edaravone (radicut), a free radical scavenger, for cardiovascular disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

main subject

heterocyclic compound

1 reference

17 September 2019

1 reference

2 October 2019

1 reference

cardiovascular disease

4 references

17 June 2019

17 September 2019

2 October 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Kiyoshi Kikuchi

1

2 references

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5 March 2020

Nobuyuki Takeshige

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Munetake Yoshitomi

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Motohiro Morioka

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Yoshinaka Murai

6

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Eiichiro Tanaka

7

2 references

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5 March 2020

language of work or name

1 reference

4 July 2013

6 references

17 June 2019

17 September 2019

2 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

27 October 2022

International Journal of Molecular Sciences

6 references

17 June 2019

17 September 2019

2 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

27 October 2022

14

2 references

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5 March 2020

issue

7

2 references

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5 March 2020

page(s)

13909-13930

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

5 March 2020

copyright license

4 references

17 June 2019

17 September 2019

2 October 2019

Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials

27 October 2022

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Atherosclerosis — An Inflammatory Disease

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Enhanced TNF alpha and oxidative stress in patients with heart failure: effect of TNF alpha on platelet O2- production

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

The antioxidant nutrients and disease prevention--what do we know and what do we need to find out?

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Cellular defense against H2O2-induced apoptosis via MAP kinase-MKP-1 pathway

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

1,026 experimental treatments in acute stroke

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

NAD(P)H oxidase: role in cardiovascular biology and disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Severe stroke induces long-lasting alterations of high-mobility group box 1.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Lifetime risks of cardiovascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Beyond neurological disease: new targets for edaravone (Review).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Regulation of inflammation and myocardial fibrosis in experimental autoimmune myocarditis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Effects of edaravone on muscle atrophy and locomotor function in patients with ischemic stroke: a randomized controlled pilot study

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Oxidative stress as a mediator of cardiovascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Atherosclerosis and oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Neuroprotective effects of free radical scavengers in stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Guidelines for the early management of adults with ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council, Clinical Cardiology Council, Cardiovascular Radiology and Intervention Council, and the A

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Therapeutic strategies for the treatment of stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Inflammation, atherosclerosis, and stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Mechanisms underlying endothelial dysfunction in diabetes mellitus: therapeutic implications

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Inflammation in areas of remote changes following focal brain lesion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Oxidative stress and vascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Pathophysiology of cerebral ischemia and brain trauma: similarities and differences

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Role of oxidative stress in atherosclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

The effect of tirilazad mesylate on infarct volume of patients with acute ischemic stroke

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Oxidative stress in arterial hypertension: role of NAD(P)H oxidase.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Inflammatory mediators and stroke: new opportunities for novel therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Redox regulation of signal transduction in cardiac and smooth muscle

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Activation of NADPH oxidase required for macrophage-mediated oxidation of low-density lipoprotein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Oxidants as stimulators of signal transduction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Antioxidants, redox-regulated transcription factors, and inflammation

28 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

28 September 2017

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone (Radicut), a free radical scavenger, is a potentially useful addition to thrombolytic therapy in patients with acute ischemic stroke

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Beneficial effects of edaravone, a novel antioxidant, in rats with dilated cardiomyopathy

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Cardioprotective effects of 3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186), a novel free radical scavenger, on acute autoimmune myocarditis in rats

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Hydroxyl radical mediates the augmented angiotensin II responses in thoracic aorta of spontaneously hypertensive rats

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Endoplasmic reticulum stress exacerbates ischemia-reperfusion-induced apoptosis through attenuation of Akt protein synthesis in human choriocarcinoma cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Protective effect of edaravone against hypoxia-reoxygenation injury in rabbit cardiomyocytes

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Angiotensin II induces monocyte chemoattractant protein-1 gene expression in rat vascular smooth muscle cells.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Endothelial function and oxidant stress.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Endothelial-derived superoxide anions in pig coronary arteries: evidence from lucigenin chemiluminescence and histochemical techniques

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Oxygen free radicals and congestive heart failure

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Edaravone: a new therapeutic approach for the treatment of acute stroke

31 May 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone attenuates cerebral ischemic injury by suppressing aquaporin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Arachidonic acid metabolites contribute to the irreversible depolarization induced by in vitro ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Effects of edaravone on reperfusion injury in patients with acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Delayed neuronal death prevented by inhibition of increased hydroxyl radical formation in a transient cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Effects of edaravone on singlet oxygen released from activated human neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone, a novel radical scavenger, inhibits oxidative modification of low-density lipoprotein (LDL) and reverses oxidized LDL-mediated reduction in the expression of endothelial nitric oxide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Contractile responses to reactive oxygen species in the canine basilar artery in vitro: selective inhibitory effect of MCI-186, a new hydroxyl radical scavenger

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone, a radical scavenger, inhibits mitochondrial permeability transition pore in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone neuroprotection effected by suppressing the gene expression of the Fas signal pathway following transient focal ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Combined argatroban and edaravone caused additive neuroprotection against 15 min of forebrain ischemia in gerbils

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone inhibits the expression of vascular endothelial growth factor in human astrocytes exposed to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Dehydroascorbic acid normalizes several markers of oxidative stress and inflammation in acute hyperglycemic focal cerebral ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Astrocytic activation and delayed infarct expansion after permanent focal ischemia in rats. Part I: enhanced astrocytic synthesis of s-100beta in the periinfarct area precedes delayed infarct expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Elevated high-mobility group box 1 levels in patients with cerebral and myocardial ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone (radical scavenger) versus sodium ozagrel (antiplatelet agent) in acute noncardioembolic ischemic stroke (EDO trial).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Does functional outcome in acute ischaemic stroke patients correlate with the amount of free-radical scavenger treatment? A retrospective study of edaravone therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Inhibition of neointimal hyperplasia development by MCI-186 is correlated with downregulation of nuclear factor-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Potent free radical scavenger, edaravone, suppresses oxidative stress-induced endothelial damage and early atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Scavenging free radicals improves endothelial dysfunction in human coronary arteries in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Oxidative stress and male IGF-1, gonadotropin and related hormones in diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Glucose increases endothelial-dependent superoxide formation in coronary arteries by NAD(P)H oxidase activation: attenuation by the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor atorvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Vascular NADH oxidase is involved in impaired endothelium-dependent vasodilation in OLETF rats, a model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Malondialdehyde, lipofuscin and activity of antioxidant enzymes during physical exercise in patients with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Antioxidant Activities and Oxidative Stress Byproducts in Human Hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Oxidative stress in leukocytes is a possible link between blood pressure, blood glucose, and C-reacting protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

The antioxidant edaravone attenuates pressure overload-induced left ventricular hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Allopurinol improves myocardial efficiency in patients with idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Increased myocardial NADPH oxidase activity in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Determination of mitochondrial nitric oxide synthase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Pressure overload-induced myocardial hypertrophy in mice does not require gp91phox

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone reduces myocardial infarct size and improves cardiac function and remodelling in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Effect of edaravone on plasma monocyte chemoattractant protein-1 levels in patients with acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Donor antioxidant strategy prolongs cardiac allograft survival by attenuating tissue dendritic cell immunogenicity(†).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Effect of edaravone, a novel free radical scavenger, supplemented to cardioplegia on myocardial function after cardioplegic arrest: in vitro study of isolated rat heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Myocardial protection of MCI-186 in rabbit ischemia-reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone prevented deteriorated cardiac function after myocardial ischemia-reperfusion via inhibiting lipid peroxidation in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Cardioprotective effect of edaravone against ischaemia-reperfusion injury in the rabbit heart before, during and after reperfusion treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Correction of defective interdomain interaction within ryanodine receptor by antioxidant is a new therapeutic strategy against heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

MCI-186 (edaravone), a novel free radical scavenger, protects against acute autoimmune myocarditis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

The antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Involvement of AMPK and MAPK signaling during the progression of experimental autoimmune myocarditis in rats and its blockade using a novel antioxidant.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Edaravone (3-Methyl-1-Phenyl-2-Pyrazolin-5-one), A Novel Free Radical Scavenger, for Treatment of Cardiovascular Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS140713909

Relationship between plasma high-mobility group box-1 levels and clinical outcomes of ischemic stroke.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Potential of edaravone for neuroprotection in neurologic diseases that do not involve cerebral infarction.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Antioxidant MCI-186 inhibits mitochondrial permeability transition pore and upregulates Bcl-2 expression

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Protective effects of MCI-186 on cerebral ischemia: possible involvement of free radical scavenging and antioxidant actions.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3742225

Lipid peroxidation and antioxidant enzyme activities in patients with type 1 diabetes mellitus

28 November 2018

1 reference

12 December 2020

Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium

1 reference

12 December 2020

Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium

1 reference

12 December 2020

Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure

1 reference

12 December 2020

Endothelium-specific activation of NAD(P)H oxidase in aortas of exogenously hyperinsulinemic rats

1 reference

12 December 2020

Reactive oxygen species in essential hypertension and non-insulin-dependent diabetes mellitus

1 reference

12 December 2020

Vascular superoxide production by NAD(P)H oxidase: association with endothelial dysfunction and clinical risk factors

1 reference

12 December 2020

Peroxynitrite is a major contributor to cytokine-induced myocardial contractile failure

1 reference

12 December 2020

Nuclear factor-kappaB immunoreactivity is present in human coronary plaque and enhanced in patients with unstable angina pectoris

1 reference

12 December 2020

Early increase of oxidative stress and reduced antioxidant defenses in patients with uncomplicated type 1 diabetes: a case for gender difference

1 reference

12 December 2020

Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats

1 reference

12 December 2020

Inhibitory effects of edaravone on the production of tumor necrosis factor-alpha in the isolated heart undergoing ischemia and reperfusion

1 reference

12 December 2020

Long-term efficacy of edaravone in patients with acute myocardial infarction

1 reference

12 December 2020

Effects of MCI-186 (edaravone), a novel free radical scavenger, upon experimental atherosclerosis in apolipoprotein E-deficient mice

1 reference

12 December 2020

5-methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling

1 reference

12 December 2020

Neuroprotection: the end of an era?

1 reference

12 December 2020

Efficacy of MCI-186, a free-radical scavenger and antioxidant, for resuscitation of nonbeating donor hearts

1 reference

12 December 2020

NXY-059 for the treatment of acute ischemic stroke

1 reference

12 December 2020

Edaravone preserves coronary microvascular endothelial function after ischemia/reperfusion on the beating canine heart in vivo

1 reference

12 December 2020

Oxidative stress in cardiovascular disease: a new avenue toward future therapeutic approaches

1 reference

12 December 2020

C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammation

1 reference

12 December 2020

Electrocardiographic and biochemical evidence for the cardioprotective effect of antioxidants in acute doxorubicin-induced cardiotoxicity in the beagle dogs

1 reference

12 December 2020

Administration of edaravone, a free radical scavenger, during t-PA infusion can enhance early recanalization in acute stroke patients--a preliminary study

1 reference

12 December 2020

A hypothesis: Edaravone exert cardioprotection partly via modulation of adiponectin

1 reference

12 December 2020

Antioxidant activity of 3-methyl-1-phenyl-2-pyrazolin-5-one

1 reference

12 December 2020

Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.

1 reference

12 December 2020

Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide

1 reference

12 December 2020

Effects of a hydroxyl radical scavenger on delayed ischemic neurological deficits following aneurysmal subarachnoid hemorrhage: results of a multicenter, placebo-controlled double-blind trial

1 reference

12 December 2020

Effect of MCI-186 on postischemic reperfusion injury in isolated rat heart

1 reference

12 December 2020

A randomized trial of tirilazad mesylate in patients with acute stroke (RANTTAS). The RANTTAS Investigators

1 reference

12 December 2020

Time course study of oxidative stress in aorta and heart of diabetic rat

1 reference

12 December 2020

Protein oxidation, tyrosine nitration, and inactivation of sarcoplasmic reticulum Ca2+-ATPase in low-frequency stimulated rabbit muscle

1 reference

12 December 2020

Long-term L-arginine supplementation improves small-vessel coronary endothelial function in humans

1 reference

12 December 2020

Inhibitory effects of antioxidants on neonatal rat cardiac myocyte hypertrophy induced by tumor necrosis factor-alpha and angiotensin II

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS140713909

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23880849%20AND%20SRC:MED&resulttype=core&format=json