TLR4/PKC-mediated tight junction modulation: a clinical marker of chemotherapy-induced gut toxicity? (Q27015742)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24310924%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Rachel J. Gibson

series ordinal

2

1 reference

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10 June 2020

Joanne Bowen

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24310924%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Richard M Logan

series ordinal

3

1 reference

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10 June 2020

language of work or name

1 reference

1 December 2014

1 reference

International Journal of Cancer

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24310924%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

135

2 references

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10 June 2020

issue

11

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10 June 2020

page(s)

2483-2492

1 reference

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Supportive care silos: time to forge cross-links, using mucositis as an example

10 June 2020

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Irinotecan-induced mucositis manifesting as diarrhoea corresponds with an amended intestinal flora and mucin profile.

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Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal?

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The structure and regulation of tight junctions

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Disruption of ZO-1/claudin-4 interaction in relation to inflammatory responses in methotrexate-induced intestinal mucositis

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Irinotecan injures tight junction and causes bacterial translocation in rat.

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Structure of the intestinal flora responsible for development of the gut immune system in a rodent model

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Toll-like receptor 4 increases intestinal permeability through up-regulation of membrane PKC activity in alcoholic steatohepatitis

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Crosstalk of tight junction components with signaling pathways

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Epithelial transport and barrier function in occludin-deficient mice

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Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice

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Assembly of the tight junction: the role of diacylglycerol

21 January 2018

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The JAM family of proteins

21 January 2018

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aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation

21 January 2018

1 reference

Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.

21 January 2018

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ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation.

21 January 2018

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Intestinal permeability in the assessment of intestinal toxicity of cytotoxic agents

21 January 2018

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Intestinal permeability in patients with chemotherapy-induced stomatitis.

21 January 2018

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Prospective evaluation of gut mucosal barrier injury following various myeloablative regimens for haematopoietic stem cell transplant

21 January 2018

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Chemotherapy-induced mucosal barrier dysfunction: an updated review on the role of intestinal tight junctions

21 January 2018

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Modification of tight junction function by protein kinase C isoforms.

21 January 2018

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Tight junctions and the modulation of barrier function in disease

21 January 2018

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Occludin: one protein, many forms

21 January 2018

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Synergistic effects of interferon gamma and tumour necrosis factor alpha on T84 cell function

21 January 2018

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Interferon-gamma and tumor necrosis factor-alpha synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression

21 January 2018

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Cytokine regulation of tight junctions

21 January 2018

1 reference

Epithelial tight junctions in intestinal inflammation

21 January 2018

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Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation

21 January 2018

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Mechanism of TNF-{alpha} modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression

21 January 2018

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TNF-alpha-induced increase in intestinal epithelial tight junction permeability requires NF-kappa B activation

21 January 2018

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Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability

21 January 2018

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Ecological and evolutionary forces shaping microbial diversity in the human intestine

21 January 2018

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Intestinal barrier function: molecular regulation and disease pathogenesis

21 January 2018

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Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation

21 January 2018

1 reference

Enteropathogenic Escherichia coli infection leads to appearance of aberrant tight junctions strands in the lateral membrane of intestinal epithelial cells

21 January 2018

1 reference

CaCo-2 cells treated with Clostridium perfringens enterotoxin form multiple large complex species, one of which contains the tight junction protein occludin

21 January 2018

1 reference

Effect of lactobacilli on paracellular permeability in the gut

21 January 2018

1 reference

Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function

21 January 2018

1 reference

Probiotic bacteria enhance murine and human intestinal epithelial barrier function

21 January 2018

1 reference

Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity

21 January 2018

1 reference

Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat.

21 January 2018

1 reference

The regulation of matrix metalloproteinases and their inhibitors.

21 January 2018

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Proteolytic processing of chemokines: implications in physiological and pathological conditions.

21 January 2018

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Matrix metalloproteinases as modulators of inflammation

21 January 2018

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Estrogen decrease in tight junctional resistance involves matrix-metalloproteinase-7-mediated remodeling of occludin

21 January 2018

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The interplay of collagen IV, tumor necrosis factor-alpha, gelatinase B (matrix metalloprotease-9), and tissue inhibitor of metalloproteases-1 in the basal lamina regulates Sertoli cell-tight junction dynamics in the rat testis

21 January 2018

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MMP9 modulates tight junction integrity and cell viability in human airway epithelia

21 January 2018

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Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation

21 January 2018

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Activation of the PKC pathway stimulates ovarian cancer cell proliferation, migration, and expression of MMP7 and MMP10.

21 January 2018

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Interleukin-1β-induced barrier dysfunction is signaled through PKC-θ in human brain microvascular endothelium

21 January 2018

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Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

21 January 2018

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Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

21 January 2018

1 reference

Relative contribution of cell contact pattern, specific PKC isoforms and gap junctional communication in tight junction assembly in the mouse early embryo.

21 January 2018

1 reference

The role of protein kinase C isoforms in modulating injury and repair of the intestinal barrier

21 January 2018

1 reference

Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro

21 January 2018

1 reference

Protein kinase C activation by Helicobacter pylori in human gastric epithelial cells limits interleukin-8 production through suppression of extracellular signal-regulated kinase

21 January 2018

1 reference

PKC eta regulates occludin phosphorylation and epithelial tight junction integrity

21 January 2018

1 reference

Protein kinase C regulates the phosphorylation and cellular localization of occludin

21 January 2018

1 reference

EGF rapidly translocates tight junction proteins from the cytoplasm to the cell-cell contact via protein kinase C activation in TMK-1 gastric cancer cells

21 January 2018

1 reference

Disruption of hepatocellular tight junctions by vascular endothelial growth factor (VEGF): a novel mechanism for tumor invasion

21 January 2018

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Regulation of airway tight junctions by proinflammatory cytokines

21 January 2018

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Serum levels of NFkappaB and pro-inflammatory cytokines following administration of mucotoxic drugs

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Severity of doxorubicin-induced small intestinal mucositis is regulated by the TLR-2 and TLR-9 pathways

21 January 2018

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Characterisation of mucosal changes in the alimentary tract following administration of irinotecan: implications for the pathobiology of mucositis.

21 January 2018

1 reference

Endotoxin tolerance attenuates LPS-induced TLR4 mobilization to lipid rafts: a condition reversed by PKC activation

21 January 2018

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Deletion of toll-like receptor-4 downregulates protein kinase C-zeta and attenuates liver injury in experimental pancreatitis.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.28656

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24310924%20AND%20SRC:MED&resulttype=core&format=json

release_mnzxvpx3h5hjffpt6xvudf3bsu

10 June 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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