Analysis of TP53 mutation spectra reveals the fingerprint of the potent environmental carcinogen, aristolochic acid (Q27021933)

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M. Moriya

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A.P. Grollman

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1 reference

M. Olivier

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language of work or name

1 reference

2013

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753

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issue

1

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page(s)

41-9

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Aristolochic acid-associated urothelial cancer in Taiwan

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Aristolochic acid and the etiology of endemic (Balkan) nephropathy

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Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy

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Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease

7 April 2017

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Tumor suppressor p53 (TP53) at the crossroads of the exposome and the cancer genome

28 September 2017

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Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts

28 September 2017

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Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid

28 September 2017

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Genetic loci that affect aristolochic acid-induced nephrotoxicity in the mouse

28 September 2017

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Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.

28 September 2017

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TP53 mutations in human cancers: origins, consequences, and clinical use

28 September 2017

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Wild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts: p53/ARF pathway disruption in spontaneous escape from senescence

28 September 2017

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Population-based case-control study of Chinese herbal products containing aristolochic acid and urinary tract cancer risk

28 September 2017

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DNA adducts of aristolochic acid II: total synthesis and site-specific mutagenesis studies in mammalian cells

28 September 2017

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Prescription profile of potentially aristolochic acid containing Chinese herbal products: an analysis of National Health Insurance data in Taiwan between 1997 and 2003.

28 September 2017

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p53 isoforms - a conspiracy to kidnap p53 tumor suppressor activity?

28 September 2017

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Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72.

28 September 2017

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Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.

28 September 2017

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Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.

28 September 2017

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TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer

28 September 2017

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MEF immortalization to investigate the ins and outs of mutagenesis

28 September 2017

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Endemic nephropathy: the case for chronic poisoning by aristolochia

28 September 2017

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p53 designer genes for the modern mouse.

28 September 2017

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Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene

28 September 2017

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Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers

28 September 2017

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TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

28 September 2017

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DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy

31 May 2018

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Etiology of endemic nephropathy

31 May 2018

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Carcinogens leave fingerprints

31 May 2018

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ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues.

31 May 2018

1 reference

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Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue® rats.

28 November 2018

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Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689860

TP53 Mutational signature for aristolochic acid: an environmental carcinogen.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689860

Risks of kidney failure associated with consumption of herbal products containing Mu Tong or Fangchi: a population-based case-control study

28 November 2018

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Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689860

Selective toxicity of aristolochic acids I and II.

28 November 2018

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Unusually high incidence of upper urinary tract urothelial carcinoma in Taiwan

28 November 2018

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Progression rate of Chinese herb nephropathy: impact of Aristolochia fangchi ingested dose

28 November 2018

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Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions.

28 November 2018

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Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.

28 November 2018

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Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi)

28 November 2018

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Upper urinary tract urothelial cancers: where it is A:T

28 November 2018

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

On the histopathogenesis of rat forestomach carcinoma caused by aristolochic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23422071

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumour induction in mice following exposure to aristolochic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23422071