Calcium-regulated transcriptional pathways in the normal and pathologic heart (Q27022874)

Jorge Fragoso-Medina

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2

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Rafael Estrada-Avilés

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3

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language of work or name

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October 2011

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63

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issue

10

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page(s)

847-55

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Cardiac excitation-contraction coupling

cites work

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Calcium cycling and signaling in cardiac myocytes.

21 January 2018

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Sarcoplasmic reticulum calsequestrins: structural and functional properties

21 January 2018

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Silencing calcineurin A subunit reduces SERCA2 expression in cardiac myocytes

21 January 2018

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Regulation of the sarcoplasmic reticulum Ca2+-ATPase expression in the hypertrophic and failing heart

21 January 2018

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Molecular mechanics of mouse cardiac myosin isoforms

21 January 2018

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Ca-dependence of isometric force kinetics in single skinned ventricular cardiomyocytes from rats.

21 January 2018

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Roles of Ca2+ and crossbridge kinetics in determining the maximum rates of Ca2+ activation and relaxation in rat and guinea pig skinned trabeculae

21 January 2018

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Excessive sarcoplasmic/endoplasmic reticulum Ca2+-ATPase expression causes increased sarcoplasmic reticulum Ca2+ uptake but decreases myocyte shortening.

21 January 2018

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Synergy between CaMKII Substrates and β-Adrenergic Signaling in Regulation of Cardiac Myocyte Ca2+ Handling

21 January 2018

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Reversal of calcium cycling defects in advanced heart failure toward molecular therapy

21 January 2018

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Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure

21 January 2018

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Ryanodine receptor phosphorylation by calcium/calmodulin-dependent protein kinase II promotes life-threatening ventricular arrhythmias in mice with heart failure

21 January 2018

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The relationship between arrhythmogenesis and impaired contractility in heart failure: role of altered ryanodine receptor function.

21 January 2018

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Late sodium current contributes to diastolic cell Ca2+ accumulation in chronic heart failure

21 January 2018

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Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts--role of late sodium current and intracellular ion accumulation

21 January 2018

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Impaired contractile function and calcium handling in hearts of cardiac-specific calcineurin b1-deficient mice

21 January 2018

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Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth

21 January 2018

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Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators

21 January 2018

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MEF2: a calcium-dependent regulator of cell division, differentiation and death

21 January 2018

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Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins

21 January 2018

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MEF2 transcriptional activity maintains mitochondrial adaptation in cardiac pressure overload

21 January 2018

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Protein kinase A-regulated assembly of a MEF2⋅HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells

21 January 2018

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Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4

21 January 2018

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Direct interaction of Ca2+/calmodulin inhibits histone deacetylase 5 repressor core binding to myocyte enhancer factor 2.

21 January 2018

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CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses

21 January 2018

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CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes

21 January 2018

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CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo

21 January 2018

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MEF2 is upregulated during cardiac hypertrophy and is required for normal post-natal growth of the myocardium

21 January 2018

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The calcineurin-myocyte enhancer factor 2c pathway mediates cardiac hypertrophy induced by endoplasmic reticulum stress in neonatal rat cardiomyocytes

21 January 2018

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Epac activation induces histone deacetylase nuclear export via a Ras-dependent signalling pathway

21 January 2018

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A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

21 January 2018

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MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes

21 January 2018

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MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.

21 January 2018

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DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

21 January 2018

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Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy

21 January 2018

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Evidence for coregulation of myocardial gene expression by MEF2 and NFAT in human heart failure

21 January 2018

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ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

21 January 2018

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Sarco/endoplasmic reticulum calcium ATPase-2 expression is regulated by ATF6 during the endoplasmic reticulum stress response: intracellular signaling of calcium stress in a cardiac myocyte model system

21 January 2018

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Coordination of growth and endoplasmic reticulum stress signaling by regulator of calcineurin 1 (RCAN1), a novel ATF6-inducible gene

21 January 2018

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Contractile arrest reveals calcium-dependent stimulation of SERCA2a mRNA expression in cultured ventricular cardiomyocytes

21 January 2018

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Control of muscle ryanodine receptor calcium release channels by proteins in the sarcoplasmic reticulum lumen

21 January 2018

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Transcriptional analysis of the human cardiac calsequestrin gene in cardiac and skeletal myocytes

21 January 2018

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Egr-1 negatively regulates calsequestrin expression and calcium dynamics in ventricular cells

21 January 2018

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Therapeutic potential of CPT I inhibitors: cardiac gene transcription as a target

21 January 2018

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SERCA2a in heart failure: role and therapeutic prospects

21 January 2018

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Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

21 January 2018

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Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation

21 January 2018

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Augmentation of left ventricular mechanics by recirculation-mediated AAV2/1-SERCA2a gene delivery in experimental heart failure

21 January 2018

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In vivo myocardial gene transfer: optimization and evaluation of intracoronary gene delivery in vivo

21 January 2018

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Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure.

21 January 2018

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Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial.

21 January 2018

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Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.545

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PubMed publication ID

21901815

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