Killing me softly--future challenges in apoptosis research (Q27025213)

5

object named as

Klaus-Michael Debatin

0 references

Mike-Andrew Westhoff

object named as

Mike-Andrew Westhoff

1

0 references

author name string

Oliver Brühl

2

1 reference

Lisa Nonnenmacher

3

1 reference

International Journal of Molecular Sciences

language of work or name

1 reference

3 March 2014

5 references

3 April 2019

20 December 2020

8 February 2021

3 October 2022

5 references

3 April 2019

20 December 2020

8 February 2021

3 October 2022

15

1 reference

issue

3

1 reference

page(s)

3746-67

1 reference

Creative Commons Attribution 3.0 Unported

copyright license

4 references

3 April 2019

20 December 2020

8 February 2021

on focus list of Wikimedia project

3 October 2022

copyright status

copyrighted

0 references

ScienceSource

0 references

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Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance

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The distribution of secondary growths in cancer of the breast. 1889

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Application of cancer genomics to solve unmet clinical needs.

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Sequential dosing in chemosensitization: targeting the PI3K/Akt/mTOR pathway in neuroblastoma

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Transitory dasatinib-resistant states in KIT(mut) t(8;21) acute myeloid leukemia cells correlate with altered KIT expression

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Inhibition of NF-κB signaling ablates the invasive phenotype of glioblastoma

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Cell adhesion to fibronectin down-regulates the expression of Spy1 and contributes to drug resistance in multiple myeloma cells

28 September 2017

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Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications

28 September 2017

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Genetic and non-genetic instability in tumor progression: link between the fitness landscape and the epigenetic landscape of cancer cells

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The pre-metastatic niche: finding common ground

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Necroptosis: the release of damage-associated molecular patterns and its physiological relevance

28 September 2017

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PI3K/Akt/mTOR pathway inhibitors in the therapy of pancreatic neuroendocrine tumors

28 September 2017

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Targeting the Akt kinase to modulate survival, invasiveness and drug resistance of cancer cells

28 September 2017

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Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors

28 September 2017

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Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway

28 September 2017

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Targeting PI3K and mTORC2 in metastatic renal cell carcinoma: new strategies for overcoming resistance to VEGFR and mTORC1 inhibitors

28 September 2017

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Clinical development of phosphatidylinositol 3-kinase inhibitors for cancer treatment

28 September 2017

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Programmed cell death and apoptosis--where it came from and where it is going: from Elie Metchnikoff to the control of caspases.

28 September 2017

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Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

28 September 2017

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Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo

28 September 2017

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Current clinical development of PI3K pathway inhibitors in glioblastoma

28 September 2017

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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

28 September 2017

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Insulin-like growth factor receptor-1 and nuclear factor κB are crucial survival signals that regulate caspase-3-mediated lens epithelial cell differentiation initiation.

28 September 2017

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Advancing cancer drug discovery towards more agile development of targeted combination therapies

28 September 2017

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Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer?

28 September 2017

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Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy

28 September 2017

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Dynamic reciprocity in the wound microenvironment

28 September 2017

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Cilengitide: the first anti-angiogenic small molecule drug candidate design, synthesis and clinical evaluation

28 September 2017

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Hammada scoparia flavonoids and rutin kill adherent and chemoresistant leukemic cells.

28 September 2017

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The PTEN phosphatase controls intestinal epithelial cell polarity and barrier function: role in colorectal cancer progression

28 September 2017

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Tracing pathway activities with kinase inhibitors and reverse phase protein arrays

28 September 2017

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Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

28 September 2017

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Mechanisms of resistance against PKC412 in resistant FLT3-ITD positive human acute myeloid leukemia cells

28 September 2017

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Small molecule integrin antagonists in cancer therapy

28 September 2017

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The PI3K/Akt/mTOR pathway as therapeutic target in neuroblastoma

28 September 2017

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Adhesion-mediated apoptosis resistance in cancer

28 September 2017

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Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

28 September 2017

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28 September 2017

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Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML.

28 September 2017

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

28 September 2017

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E-cadherin decreased human breast cancer cells sensitivity to staurosporine by up-regulating Bcl-2 expression

28 September 2017

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PI3K/Akt: getting it right matters

28 September 2017

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Bortezomib overcomes cell-adhesion-mediated drug resistance through downregulation of VLA-4 expression in multiple myeloma

28 September 2017

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PTEN: a new guardian of the genome.

28 September 2017

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PTEN and the PI3-kinase pathway in cancer

28 September 2017

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Anoikis: a necessary death program for anchorage-dependent cells

28 September 2017

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HSP70 inhibition reverses cell adhesion mediated and acquired drug resistance in multiple myeloma

28 September 2017

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Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells

28 September 2017

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Microenvironmental regulation of cancer development

28 September 2017

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Basal caspase activity promotes migration and invasiveness in glioblastoma cells

28 September 2017

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The roles of therapy-induced autophagy and necrosis in cancer treatment

28 September 2017

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Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia

28 September 2017

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Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment.

28 September 2017

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Cell adhesion-mediated radioresistance revisited.

28 September 2017

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Desmosomes: a role in cancer?

28 September 2017

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Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells

28 September 2017

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Preparing the "soil": the premetastatic niche

28 September 2017

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Claudin proteins in human cancer: promising new targets for diagnosis and therapy

28 September 2017

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Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets

28 September 2017

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The HMG-CoA reductase inhibitor simvastatin overcomes cell adhesion-mediated drug resistance in multiple myeloma by geranylgeranylation of Rho protein and activation of Rho kinase

28 September 2017

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Clinical translation of angiogenesis inhibitors

28 September 2017

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Antiangiogenic scheduling of lower dose cancer chemotherapy.

28 September 2017

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Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and gamma-irradiation

28 September 2017

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Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

28 September 2017

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The mutation rate and cancer

28 September 2017

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PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis

28 September 2017

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Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis

31 May 2018

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Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approach

31 May 2018

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Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines

31 May 2018

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Inability of Rous sarcoma virus to cause sarcomas in the avian embryo

31 May 2018

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Radiosensitization by Nifuroxime of the Hypoxic Cells in anin VitroTumour Model

31 May 2018

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Radiation-resistant tumor cells may be more sensitive in vitro

31 May 2018

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31 May 2018

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Cell adhesion to fibronectin (CAM-DR) influences acquired mitoxantrone resistance in U937 cells

31 May 2018

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Tipifarnib and bortezomib are synergistic and overcome cell adhesion-mediated drug resistance in multiple myeloma and acute myeloid leukemia

21 January 2018

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Reduction in drug-induced DNA double-strand breaks associated with beta1 integrin-mediated adhesion correlates with drug resistance in U937 cells

21 January 2018

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https://api.crossref.org/works/10.3390%2FIJMS15033746

Oroxylin A reverses CAM-DR of HepG2 cells by suppressing Integrinβ1 and its related pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Bone marrow stromal cells regulate caspase 3 activity in leukemic cells during chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Cell adhesion-mediated radioresistance (CAM-RR). Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Firategrast for relapsing remitting multiple sclerosis: a phase 2, randomised, double-blind, placebo-controlled trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Non-genetic heterogeneity--a mutation-independent driving force for the somatic evolution of tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Lessons from applied ecology: cancer control using an evolutionary double bind.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Glioblastoma survival in the United States before and during the temozolomide era.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS15033746

Adhesion-mediated intracellular redistribution of c-Fas-associated death domain-like IL-1-converting enzyme-like inhibitory protein-long confers resistance to CD95-induced apoptosis in hematopoietic cancer cell lines.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975365

Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975365

Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3975365

The association of up-regulation of X-linked inhibitor of apoptosis protein with cell adhesion-mediated drug resistance in U937 cells

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24595238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neural stem cell differentiation is dependent upon endogenous caspase 3 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24595238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Baldwin effect under multipeaked fitness landscapes: phenotypic fluctuation accelerates evolutionary rate

1 reference

https://pubmed.ncbi.nlm.nih.gov/24595238

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

0 references

1 reference

PubMed publication ID

24595238

1 reference