Patient-derived xenograft models of breast cancer and their predictive power (Q27026531)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Michael T Lewis

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2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

language of work or name

1 reference

10 February 2015

7 references

13 March 2019

3 April 2019

20 June 2019

17 June 2019

19 September 2019

3 December 2020

Breast Cancer Research

8 references

13 March 2019

3 April 2019

20 June 2019

17 June 2019

19 September 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

3 December 2020

17

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

1

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page(s)

17

2 references

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Creative Commons Attribution

8 June 2020

copyright license

6 references

13 March 2019

3 April 2019

20 June 2019

17 June 2019

19 September 2019

3 December 2020

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on focus list of Wikimedia project

ScienceSource

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Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture

21 March 2017

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21 March 2017

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Prospective identification of tumorigenic breast cancer cells

21 March 2017

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Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

21 March 2017

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Modelling vemurafenib resistance in melanoma reveals a strategy to forestall drug resistance

7 April 2017

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Whole-genome analysis informs breast cancer response to aromatase inhibition

21 March 2017

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21 March 2017

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Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype

21 March 2017

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A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

21 March 2017

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 March 2017

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The life history of 21 breast cancers

7 April 2017

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

7 April 2017

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The clonal and mutational evolution spectrum of primary triple-negative breast cancers

7 April 2017

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Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer

7 April 2017

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Cells of origin in cancer

7 April 2017

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

7 April 2017

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Supervised risk predictor of breast cancer based on intrinsic subtypes

7 April 2017

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Establishment of Patient-Derived Xenograft (PDX) Models of Human Breast Cancer

7 April 2017

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Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

28 September 2017

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Patient-derived xenograft models: an emerging platform for translational cancer research

28 September 2017

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PIK3CA mutations in androgen receptor-positive triple negative breast cancer confer sensitivity to the combination of PI3K and androgen receptor inhibitors

28 September 2017

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Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition

28 September 2017

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Molecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenografts

28 September 2017

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Interplay of choline metabolites and genes in patient-derived breast cancer xenografts

28 September 2017

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Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse

28 September 2017

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Proteomic characterization of breast cancer xenografts identifies early and late bevacizumab-induced responses and predicts effective drug combinations

28 September 2017

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Mutational analysis of breast cancer: guiding personalized treatments

28 September 2017

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A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models

28 September 2017

1 reference

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Combined targeting of mTOR and AKT is an effective strategy for basal-like breast cancer in patient-derived xenograft models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Patient-derived models of human breast cancer: protocols for in vitro and in vivo applications in tumor biology and translational medicine

28 September 2017

1 reference

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Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors

28 September 2017

1 reference

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Patient-derived breast tumor xenografts facilitating personalized cancer therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patient-derived triple-negative breast cancer xenografts

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Wnt pathway inhibition via the targeting of Frizzled receptors results in decreased growth and tumorigenicity of human tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Sequence analysis of mutations and translocations across breast cancer subtypes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Humanized mice: current states and perspectives

28 September 2017

1 reference

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Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Dual mTORC1/2 and HER2 blockade results in antitumor activity in preclinical models of breast cancer resistant to anti-HER2 therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Deconstructing the molecular portraits of breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Local regulation of human breast xenograft models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Triple-negative breast cancer: present challenges and new perspectives

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Biological determinants of endocrine resistance in breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Stromal gene expression predicts clinical outcome in breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

A new model of patient tumor-derived breast cancer xenografts for preclinical assays

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Reconstruction of functionally normal and malignant human breast tissues in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Relationships between drug activity in NCI preclinical in vitro and in vivo models and early clinical trials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Growth characteristics and metastatic properties of human breast cancer xenografts in immunodeficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4323263

Anticancer drug development: the grand challenges.

31 May 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13058-015-0523-1

Finding the tumor copycat: Therapy fails, patients don't

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13058-015-0523-1

Patient-derived first generation xenografts of non-small cell lung cancers: promising tools for predicting drug responses for personalized chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13058-015-0523-1

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13058-015-0523-1

Acquired resistance to endocrine treatments is associated with tumor-specific molecular changes in patient-derived luminal breast cancer xenografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13058-015-0523-1

Erratum: Integrated genomic analyses of ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13058-015-0523-1

Efficient engraftment of human primary breast cancer transplants in nonconditioned NOD/Scid mice

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow-Derived Monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clonogenic assay with established human tumour xenografts: correlation of in vitro to in vivo activity as a basis for anticancer drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/25849559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S13058-015-0523-1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 June 2020

1015204260

0 references

Fatcat ID

release_r5kdvv6epzg35huz2cbtt542vq

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

25849559

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849559%20AND%20SRC:MED&resulttype=core&format=json