Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis (Q27026936)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

review article

1 reference

title

Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2

John Heymach

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

author name string

Christopher Lieu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Michael Overman

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

Hai Tran

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

language of work or name

1 reference

27 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

6130-6139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition

13 February 2020

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A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of a dual VEGFR and FGFR inhibitor, brivanib, in patients with advanced or metastatic solid tumors

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Brivanib, a novel dual VEGF-R2/bFGF-R inhibitor.

31 May 2018

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Phase I safety, pharmacokinetic, and biomarker study of BIBF 1120, an oral triple tyrosine kinase inhibitor in patients with advanced solid tumors

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31 May 2018

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31 May 2018

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The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking

31 May 2018

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Biomarkers of angiogenesis and their role in the development of VEGF inhibitors

31 May 2018

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Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance

31 May 2018

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Association of computed tomography morphologic criteria with pathologic response and survival in patients treated with bevacizumab for colorectal liver metastases

31 May 2018

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Development of a fully human anti-PDGFRbeta antibody that suppresses growth of human tumor xenografts and enhances antitumor activity of an anti-VEGFR2 antibody

31 May 2018

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Biomarkers of response and resistance to antiangiogenic therapy

31 May 2018

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Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study

31 May 2018

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Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

31 May 2018

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Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study.

31 May 2018

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FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

31 May 2018

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Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting

31 May 2018

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Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor.

31 May 2018

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Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.

31 May 2018

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Basic FGF augments hypoxia induced HIF-1-alpha expression and VEGF release in T47D breast cancer cells

31 May 2018

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Patterns of somatic mutation in human cancer genomes

31 May 2018

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AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

31 May 2018

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The fibroblast growth factor-binding protein FGF-BP.

31 May 2018

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Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors

31 May 2018

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Fibroblast growth factor signaling in tumorigenesis

31 May 2018

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31 May 2018

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The role of fibroblast growth factors and their receptors in prostate cancer.

31 May 2018

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31 May 2018

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Molecular mechanisms of NCAM function

31 May 2018

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

31 May 2018

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Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism

31 May 2018

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Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

31 May 2018

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Regulation of wound healing by growth factors and cytokines

31 May 2018

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Distinct role of fibroblast growth factor-2 and vascular endothelial growth factor on tumor growth and angiogenesis

31 May 2018

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Enhancement of fibroblast growth factor (FGF) activity by an FGF-binding protein

31 May 2018

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Fibroblast growth factors

31 May 2018

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Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors

31 May 2018

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Clinical implications of circulating angiogenic factors in cancer patients

31 May 2018

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FGFs, heparan sulfate and FGFRs: complex interactions essential for development

31 May 2018

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An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.

31 May 2018

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Evidence for a role of FGF-2 and FGF receptors in the proliferation of non-small cell lung cancer cells

31 May 2018

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Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

31 May 2018

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Correlation between basic fibroblast growth factor immunostaining of stromal cells and stromelysin-3 mRNA expression in human breast carcinoma

31 May 2018

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The heparan sulfate-fibroblast growth factor family: diversity of structure and function.

31 May 2018

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Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells

31 May 2018

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A secreted FGF-binding protein can serve as the angiogenic switch in human cancer.

31 May 2018

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Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human p

31 May 2018

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Growth factors and melanomas.

31 May 2018

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31 May 2018

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Structural and functional diversity in the FGF receptor multigene family

31 May 2018

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Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

31 May 2018

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Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

31 May 2018

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Interaction of high-molecular-weight basic fibroblast growth factor with endothelium: biological activity and intracellular fate of human recombinant M(r) 24,000 bFGF.

31 May 2018

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Identification of a novel variant form of fibroblast growth factor receptor 3 (FGFR3 IIIb) in human colonic epithelium

31 May 2018

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The proto-oncogene FGF-3 is constitutively expressed in tumorigenic, but not in non-tumorigenic, clones of a human colon carcinoma cell line

31 May 2018

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Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy

31 May 2018

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Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1.

31 May 2018

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The choice between alternative IIIb and IIIc exons of the FGFR-3 gene is not strictly tissue-specific

31 May 2018

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Pituitary extracts and steroid hormones in the control of 3T3 cell growth

31 May 2018

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Human basic fibroblast growth factor: nucleotide sequence and genomic organization

31 May 2018

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Molecular characterization of fibroblast growth factor: distribution and biological activities in various tissues.

31 May 2018

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A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane

31 May 2018

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Purification and complementary DNA cloning of a receptor for basic fibroblast growth factor.

31 May 2018

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Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix

31 May 2018

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PDGF and FGF stimulate wound healing in the genetically diabetic mouse

31 May 2018

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Angiogenic growth factors

31 May 2018

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Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex

31 May 2018

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Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene

31 May 2018

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A simple, quantitative method for assessing angiogenesis and antiangiogenic agents using reconstituted basement membrane, heparin, and fibroblast growth factor

31 May 2018

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AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects.

31 May 2018

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Phase I dose-escalation study and biomarker analysis of E7080 in patients with advanced solid tumors.

31 May 2018

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E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models

28 November 2018

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A phase I pharmacokinetic and pharmacodynamic study of TKI258, an oral, multitargeted receptor tyrosine kinase inhibitor in patients with advanced solid tumors

28 November 2018

1 reference

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Tumor escape from endogenous, extracellular matrix-associated angiogenesis inhibitors by up-regulation of multiple proangiogenic factors.

28 November 2018

1 reference

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Inducible FGFR-1 activation leads to irreversible prostate adenocarcinoma and an epithelial-to-mesenchymal transition

28 November 2018

1 reference

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E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

28 November 2018

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Monoclonal antibody antagonists of hypothalamic FGFR1 cause potent but reversible hypophagia and weight loss in rodents and monkeys

28 November 2018

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Forced expression of hepatocyte-specific fibroblast growth factor 21 delays initiation of chemically induced hepatocarcinogenesis.

28 November 2018

1 reference

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Plasma basic fibroblast growth factor levels in colorectal cancer: a clinically useful assay?

28 November 2018

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Fusion of ETV6 to fibroblast growth factor receptor 3 in peripheral T-cell lymphoma with a t(4;12)(p16;p13) chromosomal translocation.

28 November 2018

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Vascular endothelial growth factor (VEGF) receptor-2 antagonists inhibit VEGF- and basic fibroblast growth factor-induced angiogenesis in vivo and in vitro

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

Fibroblast growth factors are required for efficient tumor angiogenesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

Correlation of bFGF, FGFR-1 and VEGF expression with vascularity and malignancy of human astrocytomas.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

FGF signaling in skeletal development.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

Endogenous basic fibroblast growth factor is implicated in the vascularization of the chick embryo chorioallantoic membrane.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5562355

Expression of basic fibroblast growth factor and its receptors by head and neck squamous carcinoma tumor and vascular endothelial cells

28 November 2018

1 reference

12 December 2020

Monospecific antibodies implicate basic fibroblast growth factor in normal wound repair

1 reference

12 December 2020

Regulation of the expression balance of angiopoietin-1 and angiopoietin-2 by Shh and FGF-2

1 reference

12 December 2020

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation

1 reference

12 December 2020

An FGF-binding protein (FGF-BP) exerts its biological function by parallel paracrine stimulation of tumor cell and endothelial cell proliferation through FGF-2 release

1 reference

12 December 2020

Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer

1 reference

12 December 2020

Antisense targeting of basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth

1 reference

12 December 2020

Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas

1 reference

12 December 2020

Detection of basic fibroblast growth factor mRNA in urinary bladder cancer: correlation with local relapses

1 reference

12 December 2020

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

1 reference

12 December 2020

The role of fibroblast growth factors in vascular development

1 reference

12 December 2020

The intratumoral microvessel density and expression of bFGF and nm23-H1 in colorectal cancer

1 reference

12 December 2020

Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro

1 reference

12 December 2020

Addition of bevacizumab to chemotherapy for treatment of solid tumors: similar results but different conclusions

1 reference

12 December 2020

10.1158/1078-0432.CCR-11-0659

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

release_oaiatukmifallilogn7wzobici

13 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oaiatukmifallilogn7wzobici

24 November 2022

mapped directly with Wikidata item

OpenCitations bibliographic resource ID

1893050

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21953501%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference