Marine natural products as breast cancer resistance protein inhibitors (Q27027706)

6 July 2021

marine natural product

0 references

1 reference

Lilia Cherigo

1

1 reference

Dioxelis Lopez

series ordinal

2

1 reference

Sergio Martinez-Luis

series ordinal

3

1 reference

language of work or name

1 reference

3 April 2015

11 references

20 June 2019

16 September 2019

19 September 2019

4 November 2019

28 November 2019

15 December 2019

18 December 2019

14 September 2020

18 January 2021

6 July 2021

11 references

20 June 2019

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19 September 2019

4 November 2019

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14 September 2020

18 January 2021

6 July 2021

13

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issue

4

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page(s)

2010-29

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Creative Commons Attribution

copyright license

10 references

20 June 2019

16 September 2019

19 September 2019

4 November 2019

28 November 2019

15 December 2019

18 December 2019

14 September 2020

18 January 2021

6 July 2021

0 references

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Lessons from the past and charting the future of marine natural products drug discovery and chemical biology

21 March 2017

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Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance

21 March 2017

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Combinatorial biosynthesis of antitumor indolocarbazole compounds

21 March 2017

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A multidrug resistance transporter from human MCF-7 breast cancer cells

21 March 2017

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A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance

21 March 2017

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In silico prediction of inhibition of promiscuous breast cancer resistance protein (BCRP/ABCG2)

21 March 2017

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Targeting multidrug resistance in cancer

21 March 2017

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

7 April 2017

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MBL-II-141, a chromone derivative, enhances irinotecan (CPT-11) anticancer efficiency in ABCG2-positive xenografts

7 April 2017

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Role of the breast cancer resistance protein (BCRP/ABCG2) in drug transport--an update

28 September 2017

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Lamellarin O, a pyrrole alkaloid from an Australian marine sponge, Ianthella sp., reverses BCRP mediated drug resistance in cancer cells.

28 September 2017

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Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.

28 September 2017

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Marketed marine natural products in the pharmaceutical and cosmeceutical industries: tips for success

28 September 2017

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Human ABC transporter ABCG2/BCRP expression in chemoresistance: basic and clinical perspectives for molecular cancer therapeutics.

28 September 2017

1 reference

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Marine natural products with P-glycoprotein inhibitor properties

28 September 2017

1 reference

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Cancer multidrug resistance: mechanisms involved and strategies for circumvention using a drug delivery system.

28 September 2017

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New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity

28 September 2017

1 reference

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Molecular pharmacology of ABCG2 and its role in chemoresistance

28 September 2017

1 reference

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Different strategies to overcome multidrug resistance in cancer

28 September 2017

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ABCG2: recent discovery of potent and highly selective inhibitors

28 September 2017

1 reference

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Transporters and drug-drug interactions: important determinants of drug disposition and effects

28 September 2017

1 reference

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Secalonic acid D reduced the percentage of side populations by down-regulating the expression of ABCG2.

28 September 2017

1 reference

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A review on medicinal importance, pharmacological activity and bioanalytical aspects of beta-carboline alkaloid ''Harmine''.

28 September 2017

1 reference

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On exploring structure-activity relationships

28 September 2017

1 reference

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The "specific" P-glycoprotein inhibitor Tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

2,5-diketopiperazines from the marine-derived fungus Aspergillus fumigatus YK-7.

28 September 2017

1 reference

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Investigation of chalcones and benzochalcones as inhibitors of breast cancer resistance protein

28 September 2017

1 reference

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Three new compounds from Aspergillus terreus PT06-2 grown in a high salt medium

28 September 2017

1 reference

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Systematic computational analysis of structure-activity relationships: concepts, challenges and recent advances

28 September 2017

1 reference

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Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).

28 September 2017

1 reference

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Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids

28 September 2017

1 reference

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Synthesis and structure-activity relationship of botryllamides that block the ABCG2 multidrug transporter

28 September 2017

1 reference

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Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.

28 September 2017

1 reference

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Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathway

28 September 2017

1 reference

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Botryllamides: natural product inhibitors of ABCG2

28 September 2017

1 reference

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The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach.

28 September 2017

1 reference

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A new terrein glucoside, a novel inhibitor of angiogenin secretion in tumor angiogenesis.

28 September 2017

1 reference

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Virtual screening of GPCRs: an in silico chemogenomics approach

28 September 2017

1 reference

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Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).

28 September 2017

1 reference

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Modulation of breast cancer resistance protein (BCRP/ABCG2) by non-basic chalcone analogues.

28 September 2017

1 reference

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Cytotoxic alkaloids and antibiotic nordammarane triterpenoids from the marine-derived fungus Aspergillus sydowi

28 September 2017

1 reference

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Homology modeling of breast cancer resistance protein (ABCG2).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Functionalized chalcones as selective inhibitors of P-glycoprotein and breast cancer resistance protein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Inhibition of ABCG2-mediated transport by protein kinase inhibitors with a bisindolylmaleimide or indolocarbazole structure.

28 September 2017

1 reference

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Two indolocarbazole alkaloids with apoptosis activity from a marine-derived actinomycete Z(2)039-2.

28 September 2017

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Indolocarbazole natural products: occurrence, biosynthesis, and biological activity

28 September 2017

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Purification of breast cancer resistance protein ABCG2 and role of arginine-482.

28 September 2017

1 reference

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Secalonic acid D; A cytotoxic constituent from marine lichen-derived fungus Gliocladium sp. T31.

28 September 2017

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Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan

28 September 2017

1 reference

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Regulation of BCRP/ABCG2 expression by progesterone and 17beta-estradiol in human placental BeWo cells

28 September 2017

1 reference

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Piperazinobenzopyranones and phenalkylaminobenzopyranones: potent inhibitors of breast cancer resistance protein (ABCG2).

28 September 2017

1 reference

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Drug resistance in brain diseases and the role of drug efflux transporters.

28 September 2017

1 reference

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Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

28 September 2017

1 reference

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Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A.

28 September 2017

1 reference

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Lamellarins, from A to Z: a family of anticancer marine pyrrole alkaloids

28 September 2017

1 reference

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Botryllamides E-H, four new tyrosine derivatives from the ascidian Botrylloides tyreum

28 September 2017

1 reference

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High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter

28 September 2017

1 reference

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Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing binding

28 September 2017

1 reference

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Broad-spectrum modulation of ATP-binding cassette transport proteins by the taxane derivatives ortataxel (IDN-5109, BAY 59-8862) and tRA96023.

28 September 2017

1 reference

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Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Reversal of breast cancer resistance protein–mediated drug resistance by tryprostatin A

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Inhibition of BCRP-mediated drug efflux by fumitremorgin-type indolyl diketopiperazines

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Solid phase synthesis of heterocycles by cyclization/cleavage methodologies

28 September 2017

1 reference

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Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line.

28 September 2017

1 reference

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Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

28 September 2017

1 reference

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Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C.

28 September 2017

1 reference

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Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology

28 September 2017

1 reference

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Asperjinone, a nor-neolignan, and terrein, a suppressor of ABCG2-expressing breast cancer cells, from thermophilic Aspergillus terreus

31 May 2018

1 reference

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Enhancement of osteoblast biocompatibility on titanium surface with Terrein treatment

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Terrein, a fungal metabolite, inhibits the epidermal proliferation of skin equivalents.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Functional expression of the human breast cancer resistance protein in Pichia pastoris

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

31 May 2018

1 reference

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A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2).

31 May 2018

1 reference

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Reversal of breast cancer resistance protein (BCRP/ABCG2)‐mediated drug resistance by novobiocin, a coumermycin antibiotic

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Computational classification models for predicting the interaction of drugs with P-glycoprotein and breast cancer resistance protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

A new compound, jolynamine, from marine brown alga Jolyna laminarioides.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Perspicamides A and B, quinolinecarboxylic acid derivatives from the Australian ascidian Botrylloides perspicuum.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Enhanced production of (+)-terrein in fed-batch cultivation of Aspergillus terreus strain PF26 with sodium citrate

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Weed growth inhibitors from Aspergillus fischeri TISTR 3272.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Terrein reduces pulpal inflammation in human dental pulp cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

1H and 13C NMR assignments for two oxaphenalenones bacillosporin C and D from the mangrove endophytic fungus SBE-14.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FMD13042010

Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. I. Taxonomy, fermentation, isolation and biological properties.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4413197

Secalonic acid D as a novel DNA topoisomerase I inhibitor from marine lichen-derived fungus Gliocladium sp. T31

28 November 2018

1 reference

12 December 2020

6-halogenochromones bearing tryptamine: one-step access to potent and highly selective inhibitors of breast cancer resistance protein

1 reference

12 December 2020

Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures

1 reference

12 December 2020

Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study

1 reference

12 December 2020

New lamellarin alkaloids from the australian ascidian, didemnum chartaceum

1 reference

12 December 2020

A study on the antitumoral and differentiation effects of peganum harmala derivatives in combination with ATRA on leukaemic cells

1 reference

12 December 2020

Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus

1 reference

12 December 2020

The isolation, structure and absolute configuration of secalonic acid D, the toxic metabolite of Penicillium oxalicum

1 reference

12 December 2020

Substituted chromones as highly potent nontoxic inhibitors, specific for the breast cancer resistance protein

1 reference

12 December 2020

Identifiers

DOI

10.3390/MD13042010

1 reference

3433471

3433471

1 reference

1 reference

1 reference