neomethymycin (Q27110209)

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chemical compound
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Language Label Description Also known as
English
neomethymycin
chemical compound

    Statements

    subclass of
    macrolides
    0 references
    polyketide
    0 references
    mass
    469.303953±0 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    5282033
    language of work or name
    English
    title
    Neomethymycin (English)
    retrieved
    5 October 2016
    chemical formula
    C₂₅H₄₃NO₇
    1 reference
    stated in
    PubChem
    PubChem CID
    5282033
    language of work or name
    English
    title
    Neomethymycin (English)
    retrieved
    5 October 2016
    canonical SMILES
    CC1CC(C(=O)C=CC(C(OC(=O)C(C1OC2C(C(CC(O2)C)N(C)C)O)C)C(C)O)C)C
    1 reference
    stated in
    PubChem
    PubChem CID
    5282033
    language of work or name
    English
    title
    Neomethymycin (English)
    retrieved
    5 October 2016
    isomeric SMILES
    C[C@H]1C[C@H](C(=O)/C=C/[C@H]([C@H](OC(=O)[C@@H]([C@H]1O[C@H]2[C@@H]([C@H](C[C@H](O2)C)N(C)C)O)C)[C@@H](C)O)C)C
    1 reference
    stated in
    PubChem
    PubChem CID
    5282033
    language of work or name
    English
    title
    Neomethymycin (English)
    retrieved
    5 October 2016
    found in taxon
    Streptomyces venezuelae
    12 references
    stated in
    Isolation and characterization of 10-deoxymethynolide produced by Streptomyces venezuelae
    stated in
    Biosynthesis of Desosamine: Molecular Evidence Suggesting β-Glucosylation as a Self-Resistance Mechanism in Methymycin/Neomethymycin Producing Strain,Streptomyces venezuelae
    stated in
    Biosynthesis of Desosamine: Construction of a New Methymycin/Neomethymycin Analogue by Deletion of a Desosamine Biosynthetic Gene
    stated in
    Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae
    stated in
    The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide
    stated in
    New methymycin derivatives of Streptomyces venezuelae ATCC 15439 and their inhibitory effects on human T cell proliferation mediated by PMA/ionomycin
    stated in
    Complete genome sequence of Streptomyces venezuelae ATCC 15439, a promising cell factory for production of secondary metabolites
    stated in
    Production of pikromycin using branched chain amino acid catabolism in Streptomyces venezuelae ATCC 15439
    stated in
    A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity
    stated in
    Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae
    stated in
    Macrolide biosynthesis: a single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae.
    stated in
    Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae

    Identifiers

    Reaxys registry number
    1334300
    1 reference
    stated in
    ChEBI
    ChEBI ID
    29656
    language of work or name
    English
    title
    neomethymycin (English)
    retrieved
    5 October 2016
    KEGG ID
    C11995
    1 reference
    stated in
    ChEBI
    ChEBI ID
    29656
    language of work or name
    English
    title
    neomethymycin (English)
    retrieved
    5 October 2016
     
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