(2E,4E)-dodecatetraenoic acid isobutylamide (Q27138440)

dodeca-2E,4E-dienoic acid isobutylamide (English)

7 October 2016

chemical formula

C₁₆H₂₉NO

1 reference

dodeca-2E,4E-dienoic acid isobutylamide (English)

20 November 2016

canonical SMILES

CCCCCCCC=CC=CC(=O)NCC(C)C

1 reference

dodeca-2E,4E-dienoic acid isobutylamide (English)

20 November 2016

isomeric SMILES

CCCCCCC/C=C/C=C/C(=O)NCC(C)C

1 reference

Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.

dodeca-2E,4E-dienoic acid isobutylamide (English)

20 November 2016

12 references

Amides from Achillea species and Leucocyclus formosus

Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.

Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells

Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells

Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides

Isobutylamides and a new methylbutylamide from Piper sarmentosum

N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors

Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

The endocannabinoid system as a target for alkamides from Echinacea angustifolia roots

Echinacea species and alkamides inhibit prostaglandin E(2) production in RAW264.7 mouse macrophage cells

Echinacea purpurea

16 references

Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.

Amides from Achillea species and Leucocyclus formosus

Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.

Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells

Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells

Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides

Isobutylamides and a new methylbutylamide from Piper sarmentosum

N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors

Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

The endocannabinoid system as a target for alkamides from Echinacea angustifolia roots

Activation of PPARgamma by metabolites from the flowers of purple coneflower (Echinacea purpurea).

Activation of PPARgamma by metabolites from the flowers of purple coneflower (Echinacea purpurea).

Alkamides and a neolignan from Echinacea purpurea roots and the interaction of alkamides with G-protein-coupled cannabinoid receptors.

Comparison of chemical components and antioxidants capacity of different Echinacea species

Echinacea species and alkamides inhibit prostaglandin E(2) production in RAW264.7 mouse macrophage cells

Leucocyclus formosus

12 references

Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.

Amides from Achillea species and Leucocyclus formosus

Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.

Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells

Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells

Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides

Isobutylamides and a new methylbutylamide from Piper sarmentosum

N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors

Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

The endocannabinoid system as a target for alkamides from Echinacea angustifolia roots

Echinacea species and alkamides inhibit prostaglandin E(2) production in RAW264.7 mouse macrophage cells

Piper formosum

12 references

Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.

Amides from Achillea species and Leucocyclus formosus

Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.

Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells

Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells

Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides

Isobutylamides and a new methylbutylamide from Piper sarmentosum

N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors

Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

The endocannabinoid system as a target for alkamides from Echinacea angustifolia roots

Echinacea species and alkamides inhibit prostaglandin E(2) production in RAW264.7 mouse macrophage cells

Piper retrofractum

13 references

Alkamides from Echinacea inhibit cyclooxygenase-2 activity in human neuroglioma cells.

Amides from Achillea species and Leucocyclus formosus

Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS.

Echinacea alkylamides inhibit interleukin-2 production by Jurkat T cells

Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE₂ from RAW 264.7 macrophage-like cells

Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides

Isobutylamides and a new methylbutylamide from Piper sarmentosum

N-Alkyl dien- and trienamides from the roots of Otanthus maritimus with binding affinity for opioid and cannabinoid receptors

Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

Synthesis and biological evaluation of a series of fatty acid amides from Echinacea

The endocannabinoid system as a target for alkamides from Echinacea angustifolia roots

Echinacea species and alkamides inhibit prostaglandin E(2) production in RAW264.7 mouse macrophage cells

Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-alpha-induced cell death in mouse hepatocytes

Echinacea pallida

1 reference

Comparison of chemical components and antioxidants capacity of different Echinacea species

Piper longum

1 reference

Two new amides with cytotoxic activity from the fruits of Piper longum

Piper nigrum

1 reference

New amide alkaloids from the roots of Piper nigrum

Piper peepuloides

1 reference

FURTHER CHEMICAL STUDIES OFPIPER PEEPULOIDES

Piper sintenense

1 reference

Cytotoxic amides from Piper sintenense.

Identifiers

InChI

InChI=1S/C16H29NO/c1-4-5-6-7-8-9-10-11-12-13-16(18)17-14-15(2)3/h10-13,15H,4-9,14H2,1-3H3,(H,17,18)/b11-10+,13-12+

1 reference

dodeca-2E,4E-dienoic acid isobutylamide (English)

20 November 2016

2 references

dodeca-2E,4E-dienoic acid isobutylamide (English)

20 November 2016

ChEBI release 2020-09-01

CAS Registry Number

24738-51-0

1 reference

Global Substance Registration System

UNII

5F4WO3BVS9

(2E,4E)-dodecatetraenoic acid isobutylamide (English)

20 November 2016

1 reference

(2E,4E)-N-Isobutyl-2,4-dodecadienamide (English)

20 November 2016

2 references

dodeca-2E,4E-dienoic acid isobutylamide (English)

20 November 2016

ChEBI ID

70101

mapping relation type

2 references

CHEMBL426912 (English)

20 November 2016

International Chemical Identifier

InChI

InChI=1S/C16H29NO/c1-4-5-6-7-8-9-10-11-12-13-16(18)17-14-15(2)3/h10-13,15H,4-9,14H2,1-3H3,(H,17,18)/b11-10+,13-12+

1 reference

CHEMBL426912 (English)

20 November 2016

2 references

inferred from InChIKey

splash10-0udi-3490000000-e7d212709221f3b7407b

1 reference

0 references

DSSTox substance ID

DTXSID801346924

1 reference

UNII

5F4WO3BVS9

2 references

Global Substance Registration System

UNII

5F4WO3BVS9

(2E,4E)-dodecatetraenoic acid isobutylamide (English)

20 November 2016