tanshinone IIA (Q27187517)

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chemical compound
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Language Label Description Also known as
English
tanshinone IIA
chemical compound

    Statements

    subclass of
    norabietanes
    0 references
    chemical structure
    Tanshinone IIA.svg
    895 × 940; 12 KB
    0 references
    mass
    294.125594±0 dalton
    1 reference
    stated in
    PubChem
    PubChem CID
    164676
    language of work or name
    English
    title
    Tanshinone IIA (English)
    retrieved
    10 October 2016
    chemical formula
    C₁₉H₁₈O₃
    1 reference
    stated in
    PubChem
    PubChem CID
    164676
    language of work or name
    English
    title
    Tanshinone IIA (English)
    retrieved
    20 November 2016
    canonical SMILES
    CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C
    1 reference
    stated in
    PubChem
    PubChem CID
    164676
    language of work or name
    English
    title
    Tanshinone IIA (English)
    retrieved
    20 November 2016
    found in taxon
    Salvia miltiorrhiza
    60 references
    stated in
    Protective effects of tanshinone IIA on myocardial ischemia reperfusion injury by reducing oxidative stress, HMGB1 expression, and inflammatory reaction.
    stated in
    Vascular effects of different lipophilic components of "Danshen", a traditional Chinese medicine, in the isolated porcine coronary artery
    stated in
    Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest.
    stated in
    Chinese medicinal herbs used to treat heart diseases
    stated in
    Quantitative analysis of the marker compounds in Salvia miltiorrihiza root and its phytomedicinal preparations
    stated in
    Inhibition of microsomal triglyceride transfer protein expression and atherogenic risk factor apolipoprotein B100 secretion by tanshinone IIA in HepG2 cells
    stated in
    The Genome of Salvia miltiorrhiza
    stated in
    Inhibitory activity of diacylglycerol acyltransferase by tanshinones from the root of Salvia miltiorrhiza
    stated in
    Modulating effect of tanshinones on mutagenic activity of Trp-P-1 and benzo[a]pyrene in Salmonella typhimurium
    stated in
    Abietane type diterpenoids from Salvia miltiorrhiza
    stated in
    Diterpenoids from Salvia miltiorrhiza
    stated in
    Mutagenicity of natural naphthoquinones and benzoquinones in the Salmonella/microsome test
    stated in
    Inhibition of osteoclast differentiation and bone resorption by tanshinone IIA isolated from Salvia miltiorrhiza Bunge
    stated in
    Separation of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography using stepwise elution
    stated in
    Microwave-assisted extraction of tanshinones from Salvia miltiorrhiza bunge with analysis by high-performance liquid chromatography.
    stated in
    High-performance liquid chromatography of abietane-type compounds
    stated in
    Extraction of Tanshinone IIA from Salvia miltiorrhiza bunge using supercritical fluid extraction and a new extraction technique, phytosol solvent extraction
    stated in
    Pigments from Salvia miltiorrhiza
    stated in
    Diterpenoid production in hairy root cultures of Salvia miltiorrhiza
    stated in
    Antioxidant activity of quinones extracted from tanshen (Salvia miltiorrhiza Bunge)
    stated in
    Antioxidative components of tanshen (Salvia miltiorhiza Bung)
    stated in
    Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza
    stated in
    Two novel abietane diterpenes from Salvia miltiorrhiza
    stated in
    Inhibition of mast cell degranulation by tanshinones from the roots of Salvia miltiorrhiza
    stated in
    Diterpenoid Production in Hairy Root Cultures ofSalvia miltiorrhiza
    stated in
    Enhancement of Adenylate Cyclase Activity bySalvia miltiorrhizaand Tanshinone 1IA
    stated in
    Possible active components of tan-shen (Salvia miltiorrhiza) for protection of the myocardium against ischemia-induced derangements
    stated in
    Neuroprotective effects of tanshinones in transient focal cerebral ischemia in mice
    stated in
    New platelet aggregation inhibitors from Tan-Shen; radix of Salvia miltiorrhiza Bunge
    stated in
    Isolation of an antidermatophytic substance from the root of Salvia miltiorrhiza
    stated in
    Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza Bunge
    stated in
    Danshenols A and B, New Aldose Reductase Inhibitors from the Root of Salvia miltiorhiza BUNGE.
    stated in
    CYP76AH1 from Salvia miltiorrhiza
    stated in
    Abietane diterpenes from Salvia miltiorrhiza inhibit the activation of hypoxia-inducible factor-1.
    stated in
    Cytotoxic effects of tanshinones from Salvia miltiorrhiza on doxorubicin-resistant human liver cancer cells
    stated in
    In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.
    stated in
    Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza
    stated in
    Bioactive tanshinones in Salvia miltiorrhiza inhibit the growth of prostate cancer cells in vitro and in mice
    stated in
    Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation
    stated in
    Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation
    stated in
    Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia
    stated in
    Experimental study of the anti-cancer mechanism of tanshinone IIA against human breast cancer
    stated in
    Functional proteomic and structural insights into molecular targets related to the growth inhibitory effect of tanshinone IIA on HeLa cells
    stated in
    Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells
    stated in
    Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells
    stated in
    Characterization of tanshinones in the roots of Salvia miltiorrhiza (Dan-shen) by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry
    stated in
    Development of the fingerprints for the quality of the roots of Salvia miltiorrhiza and its related preparations by HPLC-DAD and LC-MS(n)
    stated in
    Characterization of tanshinones with quinone reductase induction activity from Radix Salvia miltiorrhiza by liquid chromatography/tandem mass spectrometry
    stated in
    HPLC-based activity profiling of Salvia miltiorrhiza for MAO A and iNOS inhibitory activities
    stated in
    Nitrogen-containing compounds from Salvia miltiorrhiza
    stated in
    Cytotoxic and aromatic constituents from Salvia miltiorrhiza
    stated in
    Antiplasmodial and antitrypanosomal activity of tanshinone-type diterpenoids from Salvia miltiorrhiza.
    stated in
    On the the Chemical Composition of Salvia Miltiorrhiza (Chinese drug Tan-Shen)
    stated in
    In vitro cytotoxicity of tanshinones from Salvia miltiorrhiza
    stated in
    Diterpenoid tanshinones and phenolic acids from cultured hairy roots of Salvia miltiorrhiza Bunge and their antimicrobial activities.
    stated in
    Induction of CYP1A by a diterpene quinone tanshinone IIA isolated from a medicinal herb Salvia miltiorrhiza in C57BL/6J but not in DBA/2J mice
    stated in
    Diterpenoids from Salvia glutinosa, S. austriaca, S. tomentosa and S. verticillata roots
    stated in
    Two new icetexane diterpenoids from Salvia przewalskii
    stated in
    Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation.
    stated in
    Diterpenoids from Salvia miltiorrhiza

    Identifiers

    HSDB ID
    8104
    1 reference
    stated in
    Hazardous Substances Data Bank
    HSDB ID
    8104
    publication date
    28 October 2019
    title
    Tanshinone II (English)
    retrieved
    10 May 2021
     
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