oridonin (Q27236543)

inferred from SMILES

mass

364.189±0 dalton

1 reference

(1S,2R,5S,8R,9S,10S,11R,15S,18R)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one

Oridonin (English)

13 October 2016

2 references

inferred from InChIKey

2 references

inferred from InChIKey

(1R,2R,5R,8S,9R,10R,11S,15R,18S)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one

inferred from InChI

2 references

(1S,2S,5S,8R,9S,10S,11R,15S,18S)-9,10,15,18-tetrahydroxy-12,12-dimethyl-6-methylidene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one

inferred from InChIKey

1 reference

1 reference

inferred from InChI

chemical formula

C₂₀H₂₈O₆

1 reference

Oridonin (English)

13 October 2016

CC1(CCC(C23C1C(C(C45C2CCC(C4O)C(=C)C5=O)(OC3)O)O)O)C

1 reference

Oridonin (English)

13 October 2016

CC1(CC[C@@H]([C@]23[C@@H]1[C@@H]([C@]([C@]45[C@H]2CC[C@H]([C@H]4O)C(=C)C5=O)(OC3)O)O)O)C

1 reference

A New Diepoxy-ent-kauranoid, Rugosinin, fromIsodon rugosus

Oridonin (English)

13 October 2016

2 references

A New Diepoxy-ent-kauranoid, Rugosinin, from Isodon rugosus

Isodon japonicus

7 references

Studies on constituents of Isodon japonicus hara

ent-Kaurane diterpenoids from Isodon japonicus

Diterpenoids from Rabdosia japonica

Taibaijaponicains C and D: two new diterpenoids from Isodon japonica

Diterpenoids from Isodon japonica

Antimutagenic diterpenoids from a crude drug isodonis herba (Enmei-So).

Terpenoids. Part XV. Structure and Absolute Configuration of Oridonin isolated from Isodon japonicus and Isodon trichocarpus

Isodon trichocarpus

6 references

Studies on constituents of Isodon japonicus hara

An investigation of diterpenes from the leaves of Rabdosia trichocarpa and their antibacterial activity against oral microorganisms

Terpenoids. LIII. Antitumor activity of trichorabdals and related compounds

Terpenoids. Part XV. Structure and Absolute Configuration of Oridonin isolated from Isodon japonicus and Isodon trichocarpus

Structures of ememogin and trichorabdonin, minor diterpenoids from Rabdosia trichocarpa

Effect of oridonin, a Rabdosia diterpenoid, on radiosensitization with misonidazole

Isodon rubescens

21 references

A new diterpene glycoside from Rabdosia rubescens

Ent-kaurane diterpenoids from Isodon rubescens var. lushanensis

Cytotoxic ent-kauranoid derivatives from Isodon rubescens

Two new diterpenoids and other constituents from Isodon rubescens

Ent-kaurane diterpenoids from Rabdosia rubescens and their cytotoxic effects on human cancer cell lines

A new diterpene glycoside from Rabdosia rubescens

Cytotoxic ent-kaurane diterpenoids from Isodon rubescens var. lushiensis

Four new ent-kauranoids from Isodon rubescens var. lushanensis and data reassignment of dayecrystal B.

Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens

Optimisation of an ultrasound-assisted extraction followed by RP-HPLC separation for the simultaneous determination of oleanolic acid, ursolic acid and oridonin content in Rabdosia rubescens.

Ent-kauranoids from Isodon rubescens var. taihangensis

ent-Kaurene diterpenoids from Isodon rubescens

Ent-kaurane Diterpenoids from Isodon rubescens var. lushanensis.

Ponicidin and oridonin are responsible for the antiangiogenic activity of Rabdosia rubescens, a constituent of the herbal supplement PC SPES.

ent-Kaurane Diterpenoids from Isodon rubescens Var. lushiensis.

Oridonin induced apoptosis through Akt and MAPKs signaling pathways in human osteosarcoma cells

Oridonin induces apoptosis via PI3K/Akt pathway in cervical carcinoma HeLa cell line

Downregulation of AP-1 gene expression is an initial event in the oridonin-mediated inhibition of colorectal cancer: studies in vitro and in vivo

Induction of G(2)/M phase arrest and apoptosis by oridonin in human laryngeal carcinoma cells

Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways

ent-Abietane diterpenoids from Isodon rubescens var. rubescens.

Isodon rosthornii

1 reference

Bioactive ent-kaurane diterpenoids from Isodon rosthornii

Isodon excisoides

1 reference

Diterpenoids from <I>Isodon excisoides</I>

Isodon macrocalyx

1 reference

Structures of macrocalyxin B, F, G and H, and maoyerabdosin from Isodon macrocalyx

Isodon phyllostachys

2 references

ent‐Kaurane Diterpenoids fromIsodon phyllostachys

Three New ent-Kauranoids from Isodon phyllostachys

Isodon longitubus

3 references

Longirabdolides A and B, 6,7-seco-ent-kaurenoids from Rabdosia longituba

Isolongirabdiol, a New Diterpenoid from Rabdosia longituba

Rabdokaurins C and D, Two New Diterpenes from Rabdosia longituba.

Isodon ternifolius

2 references

Revision of the structures of isodonal, rabdolasional and related diterpenoids.

Studies on the diterpenoid constituents of Rabdosia ternifolia: Structural elucidation of new diterpenoids, rabdoternins A, B and C.

Isodon eriocalyx

1 reference

Diterpenoids from Isodon eriocalyx var. laxiflora

Identifiers

InChI

InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

1 reference

Oridonin (English)

13 October 2016

2 references

Oridonin (English)

13 October 2016

ChEBI release 2020-09-01

CAS Registry Number

28957-04-2

2 references

Global Substance Registration System

UNII

0APJ98UCLQ

oridonin (English)

13 October 2016

https://commonchemistry.cas.org/detail?cas_rn=28957-04-2

9 April 2021

1 reference

(1alpha,5beta,6beta,7beta,8alpha,9beta,10alpha,13alpha,14R)-1,6,7,14-Tetrahydroxy-7,20-epoxykaur-16-en-15-one (English)

13 October 2016

2 references

Oridonin (English)

retrieved

13 October 2016

InChIKey

ChEBI ID

138236

mapping relation type

exact match

2 references

ChEBI release 2019-10-02

International Chemical Identifier

InChI

InChI=1S/C20H28O6/c1-9-10-4-5-11-18-8-26-20(25,19(11,14(9)22)15(10)23)16(24)13(18)17(2,3)7-6-12(18)21/h10-13,15-16,21,23-25H,1,4-8H2,2-3H3/t10-,11-,12-,13+,15+,16-,18+,19-,20+/m0/s1

1 reference

CHEMBL1164920 (English)

13 October 2016

1 reference

1 reference

InChIKey

NSC number

250682

0 references

EC number

631-100-8

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Oridonin (English)

CAS no.: 28957-04-2 (English)

ECHA Substance Infocard ID

100.159.370

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Oridonin (English)

CAS no.: 28957-04-2 (English)

0 references

oridonin

0 references

UNII

0APJ98UCLQ

2 references

Global Substance Registration System

UNII

0APJ98UCLQ

oridonin (English)

retrieved

13 October 2016

InChIKey