toyocamycin (Q27282806)

TOYOCAMYCIN (English)

19 October 2016

chemical formula

C₁₂H₁₃N₅O₄

1 reference

TOYOCAMYCIN (English)

19 October 2016

canonical SMILES

C1=C(C2=C(N1C3C(C(C(O3)CO)O)O)N=CN=C2N)C#N

1 reference

TOYOCAMYCIN (English)

19 October 2016

isomeric SMILES

C1=C(C2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)N=CN=C2N)C#N

1 reference

TOYOCAMYCIN (English)

19 October 2016

found in taxon

Streptomyces sparsogenes

1 reference

Direct broth assay for sparsomycin and related nucleoside antitumor antibiotics using reversed-phase high-performance liquid chromatography

Tolypothrix tenuis

1 reference

Cytotoxic, fungicidal nucleosides from blue green algae belonging to the Scytonemataceae.

Streptomyces toyocaensis

1 reference

Pyrrolo[2,3-d]pyrimidine nucleoside antibiotics. Total synthesis and structure of toyocamycin, unamycin B, vengicide, antibiotic E-212, and sangivamycin (BA-90912)

Streptomyces diastatochromogenes

8 references

Characterization of representative rpoB gene mutations leading to a significant change in toyocamycin production of Streptomyces diastatochromogenes 1628.

Optimization of electroporation conditions for toyocamycin producer Streptomyces diastatochromogenes 1628.

ToyA, a positive pathway-specific regulator for toyocamycin biosynthesis in Streptomyces diastatochromogenes 1628

AdpAsd, a Positive Regulator for Morphological Development and Toyocamycin Biosynthesis in Streptomyces diastatochromogenes 1628

Overexpression of ribosome recycling factor is responsible for improvement of nucleotide antibiotic-toyocamycin in Streptomyces diastatochromogenes 1628.

Development of intergeneric conjugal gene transfer system in Streptomyces diastatochromogenes 1628 and its application for improvement of toyocamycin production

Substantial improvement of toyocamycin production in Streptomyces diastatochromogenes by cumulative drug-resistance mutations

Formation, regeneration, and transformation of protoplasts of Streptomyces diastatochromogenes 1628

Streptomyces rimosus

1 reference

7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine

Streptomyces

1 reference

Isolation and Structure Determination of Novel Phosphatidylinositol Kinase Inhibitors, Echiguanines A and B, from Streptomyces sp

subject has role

antineoplastic antibiotics

1 reference

Medical Subject Headings

MeSH descriptor ID

D014127

antineoplastic antimetabolite

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D014127

InChI=1S/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1

15 March 2018

Identifiers

InChI

1 reference

TOYOCAMYCIN (English)

19 October 2016

2 references

TOYOCAMYCIN (English)

19 October 2016

ChEBI release 2020-09-01

CAS Registry Number

606-58-6

2 references

Global Substance Registration System

UNII

L7995C4D7F

toyocamycin (English)

19 October 2016

https://commonchemistry.cas.org/detail?cas_rn=606-58-6

10 April 2021

1 reference

4-Amino-7-b-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (English)

19 October 2016

2 references

TOYOCAMYCIN (English)

19 October 2016

ChEBI ID

134606

mapping relation type

exact match

2 references

ChEBI release 2019-10-02

International Chemical Identifier

InChI

InChI=1S/C12H13N5O4/c13-1-5-2-17(11-7(5)10(14)15-4-16-11)12-9(20)8(19)6(3-18)21-12/h2,4,6,8-9,12,18-20H,3H2,(H2,14,15,16)/t6-,8-,9-,12-/m1/s1

1 reference

TOYOCAMYCIN (English)

19 October 2016

2 references

inferred from InChIKey

1 reference

0 references

0 references

0 references

1 reference

UNII

L7995C4D7F

2 references

Global Substance Registration System

UNII

L7995C4D7F

toyocamycin (English)

19 October 2016

Natural Product Atlas ID

NPA006347

2 references

based on heuristic

inferred from InChIKey

0 references

0 references

1 reference

inferred by common MeSH mappings on source and on Wikidata

3RE4 (English)

19 October 2016

1 reference

UMLS 2023