HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model (Q27301415)

8

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author name string

Myriam Rai

1

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Elisabetta Soragni

2

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Kai Jenssen

3

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Ryan Burnett

4

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David Herman

5

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Giovanni Coppola

6

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Massimo Pandolfo

Creative Commons Attribution 4.0 International

9

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language of work or name

English

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publication date

2008

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published in

PLOS One

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volume

3

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issue

4

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page(s)

e1958

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copyright license

start time

9 April 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Assembly of human frataxin is a mechanism for detoxifying redox-active iron

1 reference

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Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

21 March 2017

1 reference

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Translating the Histone Code

21 March 2017

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Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis

21 March 2017

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Rb interacts with histone deacetylase to repress transcription

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Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia

21 March 2017

1 reference

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Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes

21 March 2017

1 reference

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Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

21 March 2017

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Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation

21 March 2017

1 reference

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Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia

21 March 2017

1 reference

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Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia.

21 March 2017

1 reference

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Therapeutics development for triplet repeat expansion diseases

28 September 2017

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Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment.

28 September 2017

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The GAA*TTC triplet repeat expanded in Friedreich's ataxia impedes transcription elongation by T7 RNA polymerase in a length and supercoil dependent manner

28 September 2017

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RNAi-mediated suppression of the mitochondrial iron chaperone, frataxin, in Drosophila

28 September 2017

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Frataxin deficiency and mitochondrial dysfunction

28 November 2018

1 reference

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Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia.

28 November 2018

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Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo

28 November 2018

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Cloning, characterization, and properties of seven triplet repeat DNA sequences.

28 November 2018

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Knockout of frataxin gene causes embryo lethality in Arabidopsis

28 November 2018

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12 December 2020

Frataxin knockin mouse

1 reference

12 December 2020

C. elegans as a model for Friedreich Ataxia

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12 December 2020

DNA triplet repeats mediate heterochromatin-protein-1-sensitive variegated gene silencing

1 reference

12 December 2020

Phenotypic variability in Friedreich ataxia: role of the associated GAA triplet repeat expansion

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12 December 2020

Supramolecular assemblies of human frataxin are formed via subunit-subunit interactions mediated by a non-conserved amino-terminal region

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0001958

Identifiers

DOI

1 reference

ADS bibcode

2008PLoSO...3.1958R

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1 reference

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PubMed publication ID

18463734

1 reference