Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents (Q27302392)

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English	Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 June 2017

Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents (English)

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Europe PubMed Central

PubMed publication ID

26 June 2017

high-throughput screening

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4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25187658%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Benjamin L. Miller

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31 May 2020

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Craig Morrell

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31 May 2020

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Nhat-Tu Le

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31 May 2020

Yuichiro Takei

2

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31 May 2020

Yuki Izawa-Ishizawa

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31 May 2020

Hakjoo Lee

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31 May 2020

Alan V Smrcka

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31 May 2020

Kyung Ae Ko

8

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31 May 2020

Sara Ture

9

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31 May 2020

Keigi Fujiwara

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31 May 2020

Masashi Akaike

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31 May 2020

Jun-ichi Abe

13

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31 May 2020

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3 September 2014

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26 June 2017

Journal of Immunology

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31 May 2020

193

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31 May 2020

7

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31 May 2020

3803-3815

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25187658%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749510

21 March 2017

Transcriptional repression of atherogenic inflammation: modulation by PPARdelta

1 reference

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21 March 2017

MEKK3 directly regulates MEK5 activity as part of the big mitogen-activated protein kinase 1 (BMK1) signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4749510

21 March 2017

The PPAR-RXR transcriptional complex in the vasculature: energy in the balance

1 reference

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21 March 2017

Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

1 reference

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7 April 2017

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

1 reference

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28 September 2017

Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis

1 reference

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28 September 2017

A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis

1 reference

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28 September 2017

Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation

1 reference

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28 September 2017

The role of antimalarial agents in the treatment of SLE and lupus nephritis

1 reference

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28 September 2017

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice

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28 September 2017

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

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28 September 2017

Leukocyte integrin Mac-1 promotes acute cardiac allograft rejection

1 reference

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28 September 2017

PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

1 reference

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28 September 2017

Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts

1 reference

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28 September 2017

Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L)

1 reference

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28 September 2017

ERK5 activation inhibits inflammatory responses via peroxisome proliferator-activated receptor delta (PPARdelta) stimulation.

1 reference

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28 September 2017

Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

1 reference

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28 September 2017

Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure.

1 reference

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28 September 2017

Simvastatin initiated early after heart transplantation: 8-year prospective experience

1 reference

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28 September 2017

ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

1 reference

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28 September 2017

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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28 September 2017

Endothelial dysfunction, hemodynamic forces, and atherogenesis

1 reference

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28 September 2017

Endothelial function in the isolated perfused mesentery and aortae of rats with streptozotocin-induced diabetes: effect of treatment with the aldose reductase inhibitor, ponalrestat

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31 May 2018

Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation.

1 reference

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31 May 2018

Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual

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31 May 2018

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31 May 2018

Statins protect human endothelial cells from TNF-induced inflammation via ERK5 activation.

1 reference

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28 November 2018

ERK5 regulation in naïve T-cell activation and survival.

1 reference

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28 November 2018

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12 December 2020

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Mepacrine protects the isolated rat heart during hypoxia and reoxygenation--but not by inhibition of phospholipase A2

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inferred from PubMed ID database lookup

Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Fluid shear stress stimulates big mitogen-activated protein kinase 1 (BMK1) activity in endothelial cells. Dependence on tyrosine kinases and intracellular calcium

1 reference

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12 December 2020

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The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation

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10.4049/JIMMUNOL.1400571

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25187658%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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Europe PubMed Central

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31 May 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25187658%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

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