Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward (Q27305210)

9

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Adrian M Gomez

object named as

Adrian M Gomez

4

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Ream Al-Hasani

1

object named as

Ream Al-Hasani

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author name string

Jordan G McCall

2

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Gunchul Shin

3

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Gavin P Schmitz

5

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Julio M Bernardi

6

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Chang-O Pyo

7

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Sung Il Park

8

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Nicole A Crowley

10

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Michael J Krashes

11

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Bradford B Lowell

12

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Thomas L Kash

13

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John A Rogers

14

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Michael R Bruchas

CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety

15

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language of work or name

English

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publication date

2 September 2015

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published in

Neuron

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volume

87

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issue

5

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page(s)

1063-77

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cites work

1 reference

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Tuning arousal with optogenetic modulation of locus coeruleus neurons

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The dysphoric component of stress is encoded by activation of the dynorphin kappa-opioid system

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Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria

21 March 2017

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Psychotomimesis mediated by kappa opiate receptors

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CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior

21 March 2017

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Neural systems of reinforcement for drug addiction: from actions to habits to compulsion

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Neurons containing hypocretin (orexin) project to multiple neuronal systems

7 April 2017

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Coding the direct/indirect pathways by D1 and D2 receptors is not valid for accumbens projections

7 April 2017

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Spatiotemporal control of opioid signaling and behavior

28 September 2017

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A circuit mechanism for differentiating positive and negative associations

28 September 2017

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Dopaminergic and glutamatergic microdomains in a subset of rodent mesoaccumbens axons.

28 September 2017

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Opioid hedonic hotspot in nucleus accumbens shell: mu, delta, and kappa maps for enhancement of sweetness "liking" and "wanting".

28 September 2017

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An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger.

28 September 2017

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Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake

28 September 2017

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Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics

28 September 2017

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The brain reward circuitry in mood disorders

28 September 2017

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Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism

28 September 2017

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28 September 2017

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Stress produces aversion and potentiates cocaine reward by releasing endogenous dynorphins in the ventral striatum to locally stimulate serotonin reuptake

28 September 2017

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Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens

28 September 2017

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Central neuropeptide Y modulates binge-like ethanol drinking in C57BL/6J mice via Y1 and Y2 receptors

28 September 2017

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RNAscope: a novel in situ RNA analysis platform for formalin-fixed, paraffin-embedded tissues

28 September 2017

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Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction

28 September 2017

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Kappa opioid receptor signaling in the basolateral amygdala regulates conditioned fear and anxiety in rats

28 September 2017

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Hypothesis-driven structural connectivity analysis supports network over hierarchical model of brain architecture

28 September 2017

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Ligand-directed c-Jun N-terminal kinase activation disrupts opioid receptor signaling

28 September 2017

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Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking

28 September 2017

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The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors

28 September 2017

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Deficit in brain reward function and acute and protracted anxiety-like behavior after discontinuation of a chronic alcohol liquid diet in rats

28 September 2017

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Dynorphin and the pathophysiology of drug addiction

28 September 2017

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Stress increases dynorphin immunoreactivity in limbic brain regions and dynorphin antagonism produces antidepressant-like effects

28 September 2017

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Overlapping distributions of orexin/hypocretin- and dopamine-beta-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress

28 September 2017

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Convergence and segregation of ventral striatal inputs and outputs

28 September 2017

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Collateral projections from striatonigral neurons to substance P receptor-expressing intrinsic neurons in the striatum of the rat.

28 September 2017

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Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

28 September 2017

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The basal ganglia and adaptive motor control

28 September 2017

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Efferent connections of the ventral pallidum: evidence of a dual striato pallidofugal pathway

28 September 2017

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Ultrastructural examination of enkephalin and substance P input to cholinergic neurons within the rat neostriatum

28 September 2017

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Monoamine-synthesizing enzymes in central dopaminergic, noradrenergic and serotonergic neurons. Immunocytochemical localization by light and electron microscopy

28 September 2017

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Evidence for a tonic facilitatory influence of substance P on dopamine release in the nucleus accumbens

28 September 2017

1 reference

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Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance

28 September 2017

1 reference

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Distinct roles for direct and indirect pathway striatal neurons in reinforcement.

31 May 2018

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Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty

31 May 2018

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Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

31 May 2018

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A specific radioimmunoassay for the novel opioid peptide dynorphin

31 May 2018

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Aversive properties of naloxone in non-dependent (naive) rats may involve blockade of central beta-endorphin

31 May 2018

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A functional anatomical study of unipolar depression.

31 May 2018

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Cocaine self-administration differentially alters mRNA expression of striatal peptides

31 May 2018

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GABA neurons of the VTA drive conditioned place aversion.

31 May 2018

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Motivational effects of opiates in conditioned place preference and aversion paradigm--a study in three inbred strains of mice

28 November 2018

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Steady-dose and escalating-dose "binge" administration of cocaine alter expression of behavioral stereotypy and striatal preprodynorphin mRNA levels in rats

28 November 2018

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Temporal upregulation of prodynorphin mRNA in the primate striatum after cocaine self-administration

28 November 2018

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Kappa opioid receptor inhibition of glutamatergic transmission in the nucleus accumbens shell

28 November 2018

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Repeated ethanol administration induces short- and long-term changes in enkephalin and dynorphin tissue concentrations in rat brain

28 November 2018

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Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response.

28 November 2018

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Cellular sites for dynorphin activation of kappa-opioid receptors in the rat nucleus accumbens shell

28 November 2018

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Cocaine self-administration increases preprodynorphin, but not c-fos, mRNA in rat striatum.

28 November 2018

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Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated

28 November 2018

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Dynorphin-immunoreactive neurons in the rat nucleus accumbens: ultrastructure and synaptic input from terminals containing substance P and/or dynorphin

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26335648

12 December 2020

inferred from PubMed ID database lookup

Substance P in the ventral pallidum: projection from the ventral striatum, and electrophysiological and behavioral consequences of pallidal substance P

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26335648

12 December 2020

inferred from PubMed ID database lookup

Construction of implantable optical fibers for long-term optogenetic manipulation of neural circuits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26335648

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.NEURON.2015.08.019

1 reference

release_kpkfpchi4vaxbafncjkrmykecy

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kpkfpchi4vaxbafncjkrmykecy

24 November 2022

mapped directly with Wikidata item

1 reference

1 reference

PubMed publication ID

26335648

1 reference