CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies (Q27320842)

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English	CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies	scientific article

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2 March 2020

CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies (English)

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2 March 2020

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Hisashi Akiyama

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2 March 2020

Nora-Guadalupe Pina Ramirez

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2 March 2020

Suryaram Gummuluru

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Manasa V Gudheti

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11 March 2015

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2 March 2020

e1004751

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2 March 2020

3

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2 March 2020

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11 March 2015

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Siglec-1 is a novel dendritic cell receptor that mediates HIV-1 trans-infection through recognition of viral membrane gangliosides

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21 March 2017

Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cells

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21 March 2017

Sialyllactose in viral membrane gangliosides is a novel molecular recognition pattern for mature dendritic cell capture of HIV-1

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21 March 2017

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

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21 March 2017

HIV traffics through a specialized, surface-accessible intracellular compartment during trans-infection of T cells by mature dendritic cells

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

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Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations

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21 March 2017

Dendritic cells and the control of immunity

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21 March 2017

The mannose receptor

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21 March 2017

Siglecs and their roles in the immune system

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21 March 2017

Porcine sialoadhesin (CD169/Siglec-1) is an endocytic receptor that allows targeted delivery of toxins and antigens to macrophages

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21 March 2017

Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus.

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28 September 2017

Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169.

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28 September 2017

TLR-4 engagement of dendritic cells confers a BST-2/tetherin-mediated restriction of HIV-1 infection to CD4+ T cells across the virological synapse.

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28 September 2017

Innate immune sensing of HIV-1 by dendritic cells

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28 September 2017

HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells.

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28 September 2017

Transmembrane domain membrane proximal external region but not surface unit-directed broadly neutralizing HIV-1 antibodies can restrict dendritic cell-mediated HIV-1 trans-infection

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A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

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28 September 2017

3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells

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Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

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Glycosphingolipid composition of human immunodeficiency virus type 1 (HIV-1) particles is a crucial determinant for dendritic cell-mediated HIV-1 trans-infection

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28 September 2017

Capture and transfer of HIV-1 particles by mature dendritic cells converges with the exosome-dissemination pathway

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The achilles heel of the trojan horse model of HIV-1 trans-infection

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Setting the stage: host invasion by HIV.

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In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions

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Immunodeficiency virus uptake, turnover, and 2-phase transfer in human dendritic cells.

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IL-4 suppresses dendritic cell response to type I interferons.

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HIV-1 Trafficking to the Dendritic Cell-T-Cell Infectious Synapse Uses a Pathway of Tetraspanin Sorting to the Immunological Synapse

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DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection

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12 December 2020

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10.1371/JOURNAL.PPAT.1004751

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2 March 2020

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2 March 2020

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2 March 2020

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