Chemotaxis: a feedback-based computational model robustly predicts multiple aspects of real cell behaviour (Q27321808)

2

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Peter J M van Haastert

3

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Steven D Webb

4

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John A Mackenzie

5

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Robert H Insall

Navigation of chemotactic cells by parallel signaling to pseudopod persistence and orientation

6

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language of work or name

English

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publication date

May 2011

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published in

PLOS Biology

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volume

9

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issue

5

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page(s)

e1000618

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cites work

1 reference

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Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration

21 March 2017

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Persistent cell motion in the absence of external signals: a search strategy for eukaryotic cells

21 March 2017

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Emergence of large-scale cell morphology and movement from local actin filament growth dynamics

21 March 2017

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Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion

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Cell speed, persistence and information transmission during signal relay and collective migration

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Eukaryotic chemotaxis: a network of signaling pathways controls motility, directional sensing, and polarity

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Feedback loops shape cellular signals in space and time

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Analysis of WASp function during the wound inflammatory response--live-imaging studies in zebrafish larvae

28 September 2017

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Mechanism of shape determination in motile cells

28 September 2017

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Navigating through models of chemotaxis.

28 September 2017

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Exploring the control circuit of cell migration by mathematical modeling

28 September 2017

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Quantitative modeling in cell biology: what is it good for?

28 September 2017

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Directional sensing in eukaryotic chemotaxis: a balanced inactivation model

28 September 2017

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Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in dictyostelium cells.

28 September 2017

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Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis

28 September 2017

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Eukaryotic chemotaxis: distinctions between directional sensing and polarization

28 September 2017

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Calpain regulates neutrophil chemotaxis

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Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis

28 September 2017

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A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

28 September 2017

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The locomotion, shape and pseudopodial dynamics of unstimulated Dictyostelium cells are not random.

28 September 2017

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A stochastic model for leukocyte random motility and chemotaxis based on receptor binding fluctuations

28 September 2017

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The local cell curvature guides pseudopodia towards chemoattractants

28 September 2017

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A local coupling model and compass parameter for eukaryotic chemotaxis.

31 May 2018

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31 May 2018

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A mathematical model for chemoattractant gradient sensing based on receptor-regulated membrane phospholipid signaling dynamics.

21 January 2018

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Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions.

21 January 2018

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Understanding eukaryotic chemotaxis: a pseudopod-centred view

21 January 2018

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Fronts propagating with curvature-dependent speed: Algorithms based on Hamilton-Jacobi formulations

21 January 2018

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Molecular modeling of the cytoskeleton.

21 January 2018

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Adaptation in the motility response to cAMP in Dictyostelium discoideum

21 January 2018

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Receptor-mediated activation of heterotrimeric G-proteins in living cells

21 January 2018

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The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium.

21 January 2018

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Chemotaxis in the Absence of PIP3 Gradients

21 January 2018

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Rac1 and Rac2 regulate macrophage morphology but are not essential for migration

21 January 2018

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Chemotactic reorientation of granulocytes stimulated with micropipettes containing fMet-Leu-Phe

21 January 2018

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12 December 2020

Local and spatially coordinated movements in Dictyostelium discoideum amoebae during chemotaxis

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12 December 2020

Orientation of chemotactic cells and growth cones: models and mechanisms

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12 December 2020

Cell movement and shape are non-random and determined by intracellular, oscillatory rotating waves in Dictyostelium amoebae

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12 December 2020

10.1371/JOURNAL.PBIO.1000618

Identifiers

DOI

1 reference

release_bnxadtutlzf3vl2vauwilphjae

3218225

Fatcat ID

0 references

3218225

1 reference

1 reference

1 reference