A comprehensive time-course-based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set (Q27325510)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Hector R. Wong

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

4

Purvesh Khatri

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Aaditya Shidham

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

11 June 2020

language of work or name

English

0 references

publication date

13 May 2015

0 references

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

287ra71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans

11 June 2020

cites work

1 reference

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Expression profiling of human immune cell subsets identifies miRNA-mRNA regulatory relationships correlated with cell type specific expression

21 March 2017

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Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia

21 March 2017

1 reference

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Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure

21 March 2017

1 reference

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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

21 March 2017

1 reference

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Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care

21 March 2017

1 reference

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Myeloid-derived suppressor cells as regulators of the immune system

21 March 2017

1 reference

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Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

21 March 2017

1 reference

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Genomic responses in mouse models poorly mimic human inflammatory diseases

21 March 2017

1 reference

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An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

7 April 2017

1 reference

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Identification of a human neonatal immune-metabolic network associated with bacterial infection

7 April 2017

1 reference

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A meta-analysis of lung cancer gene expression identifies PTK7 as a survival gene in lung adenocarcinoma

28 September 2017

1 reference

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Gene expression profiling in sepsis: timing, tissue, and translational considerations

28 September 2017

1 reference

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Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma show alterations of genes encoding the NADPH oxidase complex and impaired reactive oxygen species synthesis capacity

28 September 2017

1 reference

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Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma

28 September 2017

1 reference

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A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

28 September 2017

1 reference

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An expression atlas of human primary cells: inference of gene function from coexpression networks

28 September 2017

1 reference

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Induced expression and functional effects of aquaporin-1 in human leukocytes in sepsis

28 September 2017

1 reference

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Gene expression profiles in febrile children with defined viral and bacterial infection

28 September 2017

1 reference

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Transcriptional instability during evolving sepsis may limit biomarker based risk stratification

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

Mycobacterium abscessus induces a limited pattern of neutrophil activation that promotes pathogen survival

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer.

28 September 2017

1 reference

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A distinct influenza infection signature in the blood transcriptome of patients with severe community-acquired pneumonia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

Does this adult patient with suspected bacteremia require blood cultures?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

rCUR: an R package for CUR matrix decomposition.

28 September 2017

1 reference

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Inflammasome-regulated cytokines are critical mediators of acute lung injury

28 September 2017

1 reference

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Signaling in innate immunity and inflammation

28 September 2017

1 reference

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The sva package for removing batch effects and other unwanted variation in high-throughput experiments

28 September 2017

1 reference

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Novel metrics for evaluating improvement in discrimination: net reclassification and integrated discrimination improvement for normal variables and nested models

28 September 2017

1 reference

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A genomic storm in critically injured humans

28 September 2017

1 reference

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Dissecting inflammatory complications in critically injured patients by within-patient gene expression changes: a longitudinal clinical genomics study

28 September 2017

1 reference

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Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma

28 September 2017

1 reference

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Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza

28 September 2017

1 reference

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Advances in microfluidic PCR for point-of-care infectious disease diagnostics.

28 September 2017

1 reference

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Validation of a gene expression-based subclassification strategy for pediatric septic shock.

28 September 2017

1 reference

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Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis

28 September 2017

1 reference

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Aberrant cell cycle and apoptotic changes characterise severe influenza A infection--a meta-analysis of genomic signatures in circulating leukocytes.

28 September 2017

1 reference

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Human transcriptome array for high-throughput clinical studies.

28 September 2017

1 reference

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Host adaptive immunity deficiency in severe pandemic influenza.

28 September 2017

1 reference

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Interferon-alpha-induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

The transcriptome of the fetal inflammatory response syndrome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

Leukocyte subset-derived genomewide expression profiles in pediatric septic shock

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis

28 September 2017

1 reference

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Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

28 September 2017

1 reference

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Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma.

28 September 2017

1 reference

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A genomic score prognostic of outcome in trauma patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4734362

Chronic lymphocytic leukemia and B and T cells differ in their response to cyclic nucleotide phosphodiesterase inhibitors.

28 September 2017

1 reference

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Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum.

28 September 2017

1 reference

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PASTAA: identifying transcription factors associated with sets of co-regulated genes

28 September 2017

1 reference

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Protein-glycan interactions in the control of innate and adaptive immune responses

28 September 2017

1 reference

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Validating the genomic signature of pediatric septic shock.

28 September 2017

1 reference

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Plasticity of the systemic inflammatory response to acute infection during critical illness: development of the riboleukogram

28 September 2017

1 reference

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Genome-level longitudinal expression of signaling pathways and gene networks in pediatric septic shock

28 September 2017

1 reference

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Regulatory T cell populations in sepsis and trauma.

28 September 2017

1 reference

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Genome-level expression profiles in pediatric septic shock indicate a role for altered zinc homeostasis in poor outcome

28 September 2017

1 reference

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Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis.

28 September 2017

1 reference

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Gene expression in blood changes rapidly in neutrophils and monocytes after ischemic stroke in humans: a microarray study

28 September 2017

1 reference

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Clinical utility of the band count

28 September 2017

1 reference

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Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool

28 September 2017

1 reference

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PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells

2 June 2018

1 reference

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Densely interconnected transcriptional circuits control cell states in human hematopoiesis

2 June 2018

1 reference

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Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program

2 June 2018

1 reference

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Gene-expression profiling of peripheral blood mononuclear cells in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Transcriptomic evidence of impaired immunoglobulin G production in fatal septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Beneficial role of endogenous immunoglobulin subclasses and isotypes in septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

The use of gene-expression profiling to identify candidate genes in human sepsis.

21 January 2018

1 reference

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Kinetics of the innate immune response after trauma: implications for the development of late onset sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Is the band count useful in the diagnosis of infection? An accuracy study in critically ill patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Robust linear dimensionality reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

21 January 2018

1 reference

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Transcript profiling of CD16-positive monocytes reveals a unique molecular fingerprint

21 January 2018

1 reference

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Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Molecular Diagnostics in Sepsis: From Bedside to Bench

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAA5993

Effects of 30 min of aerobic exercise on gene expression in human neutrophils

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25972003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Profound and persistent decrease of circulating dendritic cells is associated with ICU-acquired infection in patients with septic shock

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25972003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene expression profiles differentiate between sterile SIRS and early sepsis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25972003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.AAA5993

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

25972003

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25972003%20AND%20SRC:MED&resulttype=core&format=json