Monoclonal Antibody AP33 Defines a Broadly Neutralizing Epitope on the Hepatitis C Virus E2 Envelope Glycoprotein (Q27470798)

5

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Dimitri Lavillette

Dimitri Lavillette

4

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Alexander W. Tarr

Alexander W Tarr

2

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Jonathan Ball

Jonathan K Ball

7

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Ania M Owsianka

1

Ania Owsianka

0 references

Arvind H Patel

8

Arvind H Patel

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author name string

Vicky S Juttla

In vitro assay for neutralizing antibody to hepatitis C virus: Evidence for broadly conserved neutralization epitopes

3

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publication date

September 2005

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published in

Journal of Virology

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volume

79

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issue

17

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page(s)

11095-104

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cites work

1 reference

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CD81-Dependent Binding of Hepatitis C Virus E1E2 Heterodimers

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Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

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Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

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The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus

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Analysis of antigenicity and topology of E2 glycoprotein present on recombinant hepatitis C virus-like particles

21 March 2017

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Characterization of Low- and Very-Low-Density Hepatitis C Virus RNA-Containing Particles

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Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome

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Analysis of the C-terminal membrane anchor domains of hepatitis C virus glycoproteins E1 and E2: toward a topological model

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Mapping B-cell epitopes of hepatitis C virus E2 glycoprotein using human monoclonal antibodies from phage display libraries

21 March 2017

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Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus

21 March 2017

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Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes

21 March 2017

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Functional characterization of intracellular and secreted forms of a truncated hepatitis C virus E2 glycoprotein

21 March 2017

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Binding of hepatitis C virus to CD81

21 March 2017

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Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins

21 March 2017

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A retention signal necessary and sufficient for endoplasmic reticulum localization maps to the transmembrane domain of hepatitis C virus glycoprotein E2.

21 March 2017

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Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee

21 March 2017

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Epitope mapping of antibodies directed against hypervariable region 1 in acute self-limiting and chronic infections due to hepatitis C virus

21 March 2017

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Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein

21 March 2017

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Hepatitis C virus glycoprotein folding: disulfide bond formation and association with calnexin

21 March 2017

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Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses

21 March 2017

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Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

21 March 2017

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Cell entry of hepatitis C virus requires a set of co-receptors that include the CD81 tetraspanin and the SR-B1 scavenger receptor

21 March 2017

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Glycosylation of the hepatitis C virus envelope protein E1 occurs posttranslationally in a mannosylphosphoryldolichol-deficient CHO mutant cell line

21 March 2017

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Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus

21 March 2017

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CD81 is an entry coreceptor for hepatitis C virus

7 April 2017

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CD81 is required for hepatitis C virus glycoprotein-mediated viral infection

7 April 2017

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Global surveillance and control of hepatitis C. Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium

7 April 2017

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A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells

7 April 2017

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Genetic Heterogeneity of Hepatitis C Virus: Quasispecies and Genotypes

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Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization

7 April 2017

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Growth of human hepatoma cells lines with differentiated functions in chemically defined medium

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The natural history of community-acquired hepatitis C in the United States. The Sentinel Counties Chronic non-A, non-B Hepatitis Study Team

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Hepatitis C virus E2 has three immunogenic domains containing conformational epitopes with distinct properties and biological functions

7 April 2017

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29 September 2017

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Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner

29 September 2017

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Neutralizing antibody response during acute and chronic hepatitis C virus infection

29 September 2017

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Characterization of infectious retroviral pseudotype particles bearing hepatitis C virus glycoproteins

29 September 2017

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Characterization of functional hepatitis C virus envelope glycoproteins.

29 September 2017

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HCV E2 glycoprotein: mutagenesis of N-linked glycosylation sites and its effects on E2 expression and processing

29 September 2017

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Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate

29 September 2017

1 reference

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Glycosylation of hepatitis C virus envelope proteins

29 September 2017

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Mimotopes of the hyper variable region 1 of the hepatitis C virus induce cross-reactive antibodies directed against discontinuous epitopes.

29 September 2017

1 reference

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Monoclonal antibodies with broad specificity for hepatitis C virus hypervariable region 1 variants can recognize viral particles

29 September 2017

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Functional analysis of hepatitis C virus E2 glycoproteins and virus-like particles reveals structural dissimilarities between different forms of E2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193588

Genome of human hepatitis C virus (HCV): gene organization, sequence diversity, and variation

29 September 2017

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Mimotopes of the hepatitis C virus hypervariable region 1, but not the natural sequences, induce cross-reactive antibody response by genetic immunization

29 September 2017

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Construction and characterization of chimeric hepatitis C virus E2 glycoproteins: analysis of regions critical for glycoprotein aggregation and CD81 binding

29 September 2017

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Recombinant human monoclonal antibodies against different conformational epitopes of the E2 envelope glycoprotein of hepatitis C virus that inhibit its interaction with CD81.

29 September 2017

1 reference

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The molecular basis for responsiveness to anti-viral therapy in hepatitis C.

29 September 2017

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Characterization of aggregates of hepatitis C virus glycoproteins.

29 September 2017

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Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo.

29 September 2017

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29 September 2017

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Structure, genomic organization, replication and variability of hepatitis C virus.

29 September 2017

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Hepatitis C virus: biological and clinical consequences of genetic heterogeneity.

29 September 2017

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Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers

29 September 2017

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Immunodominant B-cell domains of hepatitis C virus envelope proteins E1 and E2 identified during early and late time points of infection

29 September 2017

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High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C.

2 June 2018

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Characterization of human monoclonal antibodies specific to the hepatitis C virus glycoprotein E2 with in vitro binding neutralization properties

2 June 2018

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Viral dynamics of hepatitis C early after orthotopic liver transplantation: evidence for rapid turnover of serum virions.

2 June 2018

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Hepatitis C quantification and sequencing in blood products, haemophiliacs, and drug users

2 June 2018

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Enveloped particles in the serum of chronic hepatitis C patients

2 June 2018

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Immunization of chimpanzees with an envelope protein-based vaccine enhances specific humoral and cellular immune responses that delay hepatitis C virus infection

27 November 2018

1 reference

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Functionally distinct helper T-cell epitopes of HCV and their role in modulation of NS3-specific, CD8+/tetramer positive CTL.

27 November 2018

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Structural features of envelope proteins on hepatitis C virus-like particles as determined by anti-envelope monoclonal antibodies and CD81 binding

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193588

Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV.

27 November 2018

1 reference

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The natural history of chronic hepatitis C in haemophiliacs

27 November 2018

1 reference

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A proposed system for the nomenclature of hepatitis C viral genotypes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193588

Differential sensitivity of hepatitis C virus quasispecies to interferon-alpha therapy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1193588

10.1128/JVI.79.17.11095-11104.2005

27 November 2018

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

16103160

1 reference