Novel pyrazolo[3,4-d]pyrimidine nucleoside analog with broad-spectrum antiviral activity (Q27477918)

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P A McKernan

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L D Nord

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R C Willis

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C R Petrie

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T M Riley

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G R Revankar

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R K Robins

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R A Smith

Antimicrobial Agents and Chemotherapy

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language of work or name

English

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publication date

October 1987

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published in

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volume

31

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page(s)

1535-41

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issue

10

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cites work

Broad-spectrum antiviral activity of 2-beta-D-ribofuranosylselenazole-4-carboxamide, a new antiviral agent

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Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

21 March 2017

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Efficacy of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide against influenza virus infections in mice

21 March 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 March 2017

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Lack of Interference of Guanosine with Ribavirin Aerosol Treatment of Influenza A Infection in Mice

7 April 2017

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Use of disposable micro tissue culture plates for antiviral and interferon induction studies

29 September 2017

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Metabolism of ribavirin in respiratory syncytial virus-infected and uninfected cells

29 September 2017

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Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line

29 September 2017

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Adenine and Adenosine Are Toxic to Human Lymphoblast Mutants Defective in Purine Salvage Enzymes

29 September 2017

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Phosphonoformate inhibition of visna virus replication

29 September 2017

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The inhibition by 6-diazo-5-oxo-L-norleucine of glutamine catabolism of the cultured human lymphoblast

29 September 2017

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Synthesis and biological activity of certain 3,4-disubstituted pyrazolo[3,4-d]pyrimidine nucleosides

29 September 2017

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Inhibitors of IMP dehydrogenase prevent sindbis virus replication and reduce GTP levels in Aedes albopictus cells

2 June 2018

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Virus-inhibitory activity of 6-azauridine dependent on cell-free extracts containing uridine kinase. I. Inhibition of plaque-formation

2 June 2018

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Mode of action of ribavirin: effect of nucleotide pool alterations on influenza virus ribonucleoprotein synthesis

2 June 2018

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Synthesis and biological activity of certain nucleoside and nucleotide derivatives of pyrazofurin

2 June 2018

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Ribavirin, tiazofurin, and selenazofurin: mononucleotides and nicotinamide adenine dinucleotide analogues. Synthesis, structure, and interactions with IMP dehydrogenase.

2 June 2018

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Orotate phosphoribosyltransferase: orotidylate decarboxylase (Ehrlich ascites cell)

2 June 2018

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Mechanism of action of the novel anticancer agent 6-fluoro-2-(2'-fluoro-1,1'-biphenyl-4-yl)-3-methyl-4-quinolinecarbo xylic acid sodium salt (NSC 368390): inhibition of de novo pyrimidine nucleotide biosynthesis

2 June 2018

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12 December 2020

Effects of acivicin and dichloroallyl lawsone upon pyrimidine biosynthesis in mouse L1210 leukemia cells

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12 December 2020

Rapid determination of nucleoside kinase and nucleotidase activities with tritium-labeled substrates

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12 December 2020

Kinetic properties and inhibition of orotidine 5'-phosphate decarboxylase. Effects of some allopurinol metabolites on the enzyme

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12 December 2020

Effect of plasma concentrations of uridine on pyrimidine biosynthesis in cultured L1210 cells

1 reference

12 December 2020

Identifiers

DOI

10.1128/AAC.31.10.1535

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3845575

3845575

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1 reference

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