Cyclophilin A Is an Essential Cofactor for Hepatitis C Virus Infection and the Principal Mediator of Cyclosporine Resistance In Vitro (Q27486118)

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Jason M Robotham

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Heather B Nelson

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Andre Irsigler

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Rachael Kenworthy

Characterization of Hepatitis C Virus Subgenomic Replicon Resistance to Cyclosporine In Vitro

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publication date

June 2008

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published in

Journal of Virology

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volume

82

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issue

11

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page(s)

5269-78

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cites work

1 reference

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Participation of Rab5, an Early Endosome Protein, in Hepatitis C Virus RNA Replication Machinery

20 March 2017

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Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

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NIM811, a Cyclophilin Inhibitor, Exhibits Potent In Vitro Activity against Hepatitis C Virus Alone or in Combination with Alpha Interferon

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Diverse Effects of Cyclosporine on Hepatitis C Virus Strain Replication

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Robust production of infectious hepatitis C virus (HCV) from stably HCV cDNA-transfected human hepatoma cells

20 March 2017

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Quantitative Analysis of the Hepatitis C Virus Replication Complex

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20 March 2017

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20 March 2017

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20 March 2017

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Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells

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20 March 2017

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Cyclophilin A complexed with a fragment of HIV-1 gag protein: insights into HIV-1 infectious activity

20 March 2017

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Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid

20 March 2017

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Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A

20 March 2017

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X-ray structure of a cyclophilin B/cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domain

20 March 2017

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The cyclophilin multigene family of peptidyl-prolyl isomerases. Characterization of three separate human isoforms

20 March 2017

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Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

20 March 2017

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Complete replication of hepatitis C virus in cell culture

20 March 2017

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Cyclophilin, TRIM5, and innate immunity to HIV-1

20 March 2017

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Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

20 March 2017

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An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

20 March 2017

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20 March 2017

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Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1

7 April 2017

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7 April 2017

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Cyclophilin: a specific cytosolic binding protein for cyclosporin A

7 April 2017

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7 April 2017

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Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infection

29 September 2017

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The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro

29 September 2017

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Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins

29 September 2017

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29 September 2017

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Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

29 September 2017

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29 September 2017

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29 September 2017

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Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication

29 September 2017

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Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein

29 September 2017

1 reference

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NMR studies of [U-13C]cyclosporin A bound to human cyclophilin B.

29 September 2017

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Evaluation of a cyclophilin inhibitor in hepatitis C virus-infected chimeric mice in vivo

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395199

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2395199

GRP78 induction by cyclosporin A in human HeLa cells

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18385230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.02614-07

1 reference

1 reference

1 reference

PubMed publication ID

18385230

1 reference