Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity (Q27487383)

1

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Sonja M Best

2

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Stephen F Porcella

4

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James B Wolfinbarger

5

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Marshall E Bloom

Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks

6

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language of work or name

English

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publication date

25 November 2008

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published in

Virology

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volume

381

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issue

2

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page(s)

268-76

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cites work

1 reference

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A Combination of Naturally Occurring Mutations in North American West Nile Virus Nonstructural Protein Genes and in the 3' Untranslated Region Alters Virus Phenotype

20 March 2017

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A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis

20 March 2017

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The West Nile virus mutant spectrum is host-dependant and a determinant of mortality in mice

20 March 2017

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A tick-borne Langat virus mutant that is temperature sensitive and host range restricted in neuroblastoma cells and lacks neuroinvasiveness for immunodeficient mice

20 March 2017

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Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing

20 March 2017

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Size heterogeneity in the 3' noncoding region of South American isolates of yellow fever virus

20 March 2017

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Visualization of membrane protein domains by cryo-electron microscopy of dengue virus

20 March 2017

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Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in vero cells or human liver cells and attenuated in mice

20 March 2017

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Attenuation markers of a candidate dengue type 2 vaccine virus, strain 16681 (PDK-53), are defined by mutations in the 5' noncoding region and nonstructural proteins 1 and 3

20 March 2017

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Identification of specific nucleotide sequences within the conserved 3'-SL in the dengue type 2 virus genome required for replication

20 March 2017

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Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4

20 March 2017

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The envelope glycoprotein from tick-borne encephalitis virus at 2 A resolution

20 March 2017

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The course of Langat virus infection in mice

20 March 2017

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An animal model for the tickborne flavivirus--Omsk hemorrhagic fever virus

20 March 2017

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Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population

20 March 2017

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Crystal structure of the catalytic domain of Japanese encephalitis virus NS3 helicase/nucleoside triphosphatase at a resolution of 1.8 A.

7 April 2017

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Mutations in West Nile virus nonstructural proteins that facilitate replicon persistence in vitro attenuate virus replication in vitro and in vivo

29 September 2017

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Role of the mutant spectrum in adaptation and replication of West Nile virus

29 September 2017

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A single M protein mutation affects the acid inactivation threshold and growth kinetics of a chimeric flavivirus.

29 September 2017

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Microevolution of tick-borne encephalitis virus in course of host alternation

29 September 2017

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Direct repeats in the 3' untranslated regions of mosquito-borne flaviviruses: possible implications for virus transmission.

29 September 2017

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Cell-specific adaptation of two flaviviruses following serial passage in mosquito cell culture

29 September 2017

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A single amino acid substitution in the central portion of the West Nile virus NS4B protein confers a highly attenuated phenotype in mice.

29 September 2017

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Long-term transmission of defective RNA viruses in humans and Aedes mosquitoes

29 September 2017

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Comparison of live and inactivated tick-borne encephalitis virus vaccines for safety, immunogenicity and efficacy in rhesus monkeys

29 September 2017

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Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication

29 September 2017

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The topology of bulges in the long stem of the flavivirus 3' stem-loop is a major determinant of RNA replication competence.

29 September 2017

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Common E protein determinants for attenuation of glycosaminoglycan-binding variants of Japanese encephalitis and West Nile viruses

29 September 2017

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Dynamics of infection in tick vectors and at the tick-host interface.

29 September 2017

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Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells

29 September 2017

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Mutations in the NS3 gene and 3'-NCR of Japanese encephalitis virus isolated from an unconventional ecosystem and implications for natural attenuation of the virus

29 September 2017

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Infectious cDNA clone of attenuated Langat tick-borne flavivirus (strain E5) and a 3' deletion mutant constructed from it exhibit decreased neuroinvasiveness in immunodeficient mice

29 September 2017

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Infectious cDNA clones of Langat tick-borne flavivirus that differ from their parent in peripheral neurovirulence

29 September 2017

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An improved micromethod for infectivity assays and neutralization tests of dengue viruses

29 September 2017

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Experimental transmission of Powassan virus (Flaviviridae) by Ixodes scapularis ticks (Acari:Ixodidae).

29 September 2017

1 reference

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Change in phenotype of tick-borne encephalitis virus following passage in Ixodes ricinus ticks and associated amino acid substitution in the envelope protein

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592254

Establishment, maintenance and description of cell lines from the tick Ixodes scapularis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592254

Reverted virulence of attenuated tick-borne encephalitis virus mutant is not accompanied with the changes in deduced viral envelope protein amino acid sequence.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592254

Localization of Powassan virus in Dermacentor andersoni ticks by immunofluorescence

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592254

27 November 2018

Tick-borne encephalitis

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Crossref

https://api.crossref.org/works/10.1016%2FJ.VIROL.2008.08.030

[Changes in the host-dependent characteristics of the tick-borne encephalitis virus during its adaptation to ticks and its readaptation to white mice]

7 January 2021

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18823640