Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice (Q27490446)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Hepatitis C virus proteins induce lipogenesis and defective triglyceride secretion in transgenic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

1 reference

1 reference

1 reference

Jean-Michel Pawlotsky

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Fabienne Foufelle

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

7

Stanley M Lemon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Hervé Lerat

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Hélène L Kammoun

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Isabelle Hainault

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Emilie Mérour

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Martin R Higgs

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Céline Callens

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

6 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

284

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

33466-33474

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and production

9 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Involvement of endoplasmic reticulum chaperones in the folding of hepatitis C virus glycoproteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

The lipid droplet is an important organelle for hepatitis C virus production

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Morphological changes in intracellular lipid droplets induced by different hepatitis C virus genotype core sequences and relationship with steatosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Activation of sterol regulatory element-binding protein 1c and fatty acid synthase transcription by hepatitis C virus non-structural protein 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Disrupting the association of hepatitis C virus core protein with lipid droplets correlates with a loss in production of infectious virus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

The hepatitis C virus life cycle as a target for new antiviral therapies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

HCV core protein induces hepatic lipid accumulation by activating SREBP1 and PPARgamma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Up-regulation of fatty acid synthase promoter by hepatitis C virus core protein: genotype-3a core has a stronger effect than genotype-1b core

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatitis C virus-induced hepatocellular steatosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Histopathology of HCV infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Serum lipid pattern in chronic hepatitis C: histological and virological correlations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatitis C virus core protein inhibits microsomal triglyceride transfer protein activity and very low density lipoprotein secretion: a model of viral-related steatosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

The histological features of chronic hepatitis C and autoimmune chronic hepatitis: a comparative analysis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

National Institutes of Health Consensus Development Conference Statement: Management of hepatitis C: 2002--June 10-12, 2002.

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Hepatitis C virus induced hypobetalipoproteinemia: a possible mechanism for steatosis in chronic hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Treatment of hepatitis C virus with peg-interferon and ribavirin combination therapy significantly affects lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Different mechanisms of steatosis in hepatitis C virus genotypes 1 and 3 infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Hepatitis C virus genotype 3 is cytopathic to hepatocytes: Reversal of hepatic steatosis after sustained therapeutic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Hepatitis C virus and liver steatosis: is it the virus? Yes it is, but not always

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Expression of liver steatosis in hepatitis C virus infection and pattern of response to alpha-interferon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Increased liver pathology in hepatitis C virus transgenic mice expressing the hepatitis B virus X protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Impaired clearance of virus-infected hepatocytes in transgenic mice expressing the hepatitis C virus polyprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Associations between hepatitis C viremia and low serum triglyceride and cholesterol levels: a community-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.019810

Alcohol, metabolic syndrome and obesity: impact on treatment efficacy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatitis C virus-associated hypobetalipoproteinemia is correlated with plasma viral load, steatosis, and liver fibrosis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2785191

Hepatic steatosis: a specific sign of hepatitis C reinfection after liver transplantation

27 November 2018

1 reference

12 December 2020

The development of fatty liver is accelerated in transgenic mice expressing cynomolgus monkey cholesteryl ester transfer protein

1 reference

12 December 2020

Liver microsomal triglyceride transfer protein is involved in hepatitis C liver steatosis

1 reference

12 December 2020

Investigation of the role of SREBP-1c in the pathogenesis of HCV-related steatosis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.019810

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19808675%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

19808675

2 references