Latent Membrane Protein 1 as a molecular adjuvant for single-cycle lentiviral vaccines (Q27497985)

2

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Liguo Niu

3

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Saravana K Kanagavelu

4

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Andrew R Rahmberg

5

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Richard S Kornbluth

6

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David T Evans

7

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Geoffrey W Stone

Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines.

8

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publication date

18 May 2011

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published in

Retrovirology

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volume

8

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issue

1

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page(s)

39

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cites work

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CD40L expressed from the canarypox vector, ALVAC, can boost immunogenicity of HIV-1 canarypox vaccine in mice and enhance the in vitro expansion of viral specific CD8+ T cell memory responses from HIV-1-infected and HIV-1-uninfected individuals

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Macaque multimeric soluble CD40 ligand and GITR ligand constructs are immunostimulatory molecules in vitro

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Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239

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EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching

29 September 2017

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Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.

29 September 2017

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CD40-activated macrophages become highly susceptible to X4 strains of human immunodeficiency virus type 1.

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29 September 2017

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Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry

29 September 2017

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Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins

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Activation of the p38 mitogen-activated protein kinase pathway by Epstein-Barr virus-encoded latent membrane protein 1 coregulates interleukin-6 and interleukin-8 production

29 September 2017

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The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

29 September 2017

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Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1).

29 September 2017

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A fusion of the EBV latent membrane protein-1 (LMP1) transmembrane domains to the CD40 cytoplasmic domain is similar to LMP1 in constitutive activation of epidermal growth factor receptor expression, nuclear factor-kappa B, and stress-activated prot

29 September 2017

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Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

29 September 2017

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Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist

29 September 2017

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The Epstein-Barr virus LMP1 cytoplasmic carboxy terminus is essential for B-lymphocyte transformation; fibroblast cocultivation complements a critical function within the terminal 155 residues.

29 September 2017

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29 September 2017

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The Epstein-Barr virus latent membrane protein-1 (LMP1) mediates activation of NF-kappa B and cell surface phenotype via two effector regions in its carboxy-terminal cytoplasmic domain.

2 June 2018

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Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis

2 June 2018

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Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death

2 June 2018

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The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B

2 June 2018

1 reference

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Mimicry of CD40 signals by Epstein-Barr virus LMP1 in B lymphocyte responses

2 June 2018

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Viral evolution as a tool to improve the tetracycline-regulated gene expression system

21 January 2018

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IL-1 beta enhances CD40 ligand-mediated cytokine secretion by human dendritic cells (DC): a mechanism for T cell-independent DC activation

21 January 2018

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based on heuristic

Use of adenoviruses encoding CD40L or IL-2 against B cell lymphoma

1 reference

PubMed

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