Amino acid starvation-responsive transcription factor GCN4 YEL009C (Q27547678)

DNA-binding transcription factor activity

3 references

9 May 2019

The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

1 reference

9 May 2019

Disrupting vesicular trafficking at the endosome attenuates transcriptional activation by Gcn4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

1 reference

9 May 2019

Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

identical protein binding

IPI

8 references

9 May 2019

Interaction network and localization of Brucella abortus membrane proteins involved in the synthesis, transport, and succinylation of cyclic β-1,2-glucans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Molecular basis of coiled-coil oligomerization-state specificity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

A conditional two-hybrid (C2H) system for the detection of protein-protein interactions that are mediated by post-translational modification.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Dissecting virulence pathways of Mycobacterium tuberculosis through protein-protein association.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Minor pseudopilin self-assembly primes type II secretion pseudopilus elongation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

Interaction network and localization of Brucella abortus membrane proteins involved in the synthesis, transport, and succinylation of cyclic β-1,2-glucans.

IPI

protein self-association

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

sequence-specific DNA binding

IPI

5 references

10 September 2018

Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

10 September 2018

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

10 September 2018

GCN4 protein, synthesized in vitro, binds HIS3 regulatory sequences: implications for general control of amino acid biosynthetic genes in yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

10 September 2018

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

10 September 2018

Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

sequence-specific DNA binding

6 references

9 May 2019

Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

GCN4 protein, synthesized in vitro, binds HIS3 regulatory sequences: implications for general control of amino acid biosynthetic genes in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Transcriptional-translational regulatory circuit in Saccharomyces cerevisiae which involves the GCN4 transcriptional activator and the GCN2 protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

High-resolution DNA-binding specificity analysis of yeast transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Amino acid-dependent Gcn4p stability regulation occurs exclusively in the yeast nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Nuclear import of yeast Gcn4p requires karyopherins Srp1p and Kap95p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

transcription regulator complex

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

positive regulation of transcription initiation from RNA polymerase II promoter

biological process

positive regulation of RNA polymerase II transcription preinitiation complex assembly

IGI

3 references

9 May 2019

An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Disrupting vesicular trafficking at the endosome attenuates transcriptional activation by Gcn4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels

1 reference

9 May 2019

Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

regulation of transcription, DNA-templated

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

nitrogen catabolite activation of transcription from RNA polymerase II promoter

1 reference

24 April 2018

Yeast response and tolerance to polyamine toxicity involving the drug : H+ antiporter Qdr3 and the transcription factors Yap1 and Gcn4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

cellular amino acid biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

transcription, DNA-templated

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P03069&geneProductId=UniProtKB:P03069

positive regulation of autophagy

1 reference

9 May 2019

A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation

1 reference

9 May 2019

A large-scale analysis of autophagy-related gene expression identifies new regulators of autophagy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

negative regulation of transcription by RNA polymerase II

3 references

9 May 2019

The transcription factor GCN4 regulates PHM8 and alters triacylglycerol metabolism in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

nitrogen catabolite activation of transcription from RNA polymerase II promoter

response to organic substance

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

positive regulation of transcription by RNA polymerase II

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

RNA polymerase II preinitiation complex assembly

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

positive regulation of cellular response to amino acid starvation

3 references

9 May 2019

Positive regulation in the general amino acid control of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Positive regulation in the general amino acid control of Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03069

Basic-leucine zipper domain

has part(s)

1 reference

stated in

InterPro Release 71.0