SCF ubiquitin ligase complex subunit GRR1 YJR090C (Q27548121)

http://www.ebi.ac.uk/interpro/protein/P24814

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

F-box protein

1 reference

based on heuristic

inferred from protein domain or family

Leucine-rich repeat, cysteine-containing subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

ubiquitin-protein transferase activity

1 reference

10 September 2018

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

protein-macromolecule adaptor activity

IDA

4 references

10 September 2018

An essential function of Grr1 for the degradation of Cln2 is to act as a binding core that links Cln2 to Skp1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

An essential function of Grr1 for the degradation of Cln2 is to act as a binding core that links Cln2 to Skp1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

7 references

10 September 2018

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

A global protein kinase and phosphatase interaction network in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

Cloning by pathway activation in yeast: identification of an Arabidopsis thaliana F-box protein that can turn on glucose repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

SCF ubiquitin ligase complex

1 reference

10 September 2018

The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

1 reference

10 September 2018

Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

1 reference

10 September 2018

Nuclear-specific degradation of Far1 is controlled by the localization of the F-box protein Cdc4.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

cellular response to methylmercury

IDA

biological process

1 reference

16 July 2018

Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

mitotic cell cycle G1 arrest in response to pheromone

IMP

1 reference

16 July 2018

The ubiquitin ligase SCFGrr1 is necessary for pheromone sensitivity in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

IMP

1 reference

16 July 2018

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

protein polyubiquitination

IPI

1 reference

16 July 2018

A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

glucose metabolic process

IMP

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

protein ubiquitination

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

carbohydrate metabolic process

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

G1/S transition of mitotic cell cycle

1 reference

16 July 2018

Eliminating all obstacles: regulated proteolysis in the eukaryotic cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

1 reference

10 September 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24814&geneProductId=UniProtKB:P24814

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

IBA

Leucine-rich repeat, cysteine-containing subtype

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24814

F-box domain

1 reference

stated in

InterPro Release 71.0