Histone methyltransferase SET2 YJL168C (Q27549269)

http://www.ebi.ac.uk/interpro/protein/P46995

WW domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P46995

Set2 Rpb1 interacting domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P46995

Post-SET domain, protein family

1 reference

Set2 Rpb1 interacting domain, protein family

1 reference

SET domain, protein family

1 reference

WW domain, protein family

1 reference

AWS domain, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

histone methyltransferase activity (H3-K36 specific)

3 references

27 February 2018

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

methyltransferase activity

IDA

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

histone methyltransferase activity (H3-K36 specific)

4 references

9 May 2019

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

4 references

27 February 2018

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

1 reference

9 May 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

5 references

14 February 2019

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

14 February 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

transcription, DNA-templated

IBA

biological process

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

DNA-templated transcription, elongation

3 references

14 February 2019

The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

14 February 2019

The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

negative regulation of reciprocal meiotic recombination

IDA

1 reference

9 May 2019

The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

negative regulation of histone H3-K9 acetylation

1 reference

9 May 2019

Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

regulation of histone exchange

1 reference

9 May 2019

Set2 methylation of histone H3 lysine 36 suppresses histone exchange on transcribed genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

regulation of DNA-dependent DNA replication initiation

1 reference

9 May 2019

Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

DNA-templated transcription, termination

1 reference

9 May 2019

Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

negative regulation of antisense RNA transcription

1 reference

9 May 2019

Nascent transcript sequencing visualizes transcription at nucleotide resolution

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

positive regulation of histone acetylation

1 reference

9 May 2019

NuA4 lysine acetyltransferase Esa1 is targeted to coding regions and stimulates transcription elongation with Gcn5.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

1 reference

9 May 2019

Effect of histone methyltransferase gene mutations on sporulation in S. cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription

histone deacetylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

negative regulation of histone H3-K14 acetylation

1 reference

9 May 2019

Histone H3K4 and K36 methylation, Chd1 and Rpd3S oppose the functions of Saccharomyces cerevisiae Spt4-Spt5 in transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

histone H3-K36 methylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

histone lysine methylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

regulation of transcription, DNA-templated

4 references

27 February 2018

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

27 February 2018

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P46995&geneProductId=UniProtKB:P46995

regulation of transcription, DNA-templated

IDA

4 references

9 May 2019

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46995

IBA

has part(s)

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference