Rho family GTPase CDC42 YLR229C (Q27549852)

http://www.ebi.ac.uk/interpro/protein/P19073

cdc42

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19073

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Small GTP-binding protein domain family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

10 references

14 February 2019

Interaction with the SH3 domain protein Bem1 regulates signaling by the Saccharomyces cerevisiae p21-activated kinase Ste20

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Association of the Rho family small GTP-binding proteins with Rho GDP dissociation inhibitor (Rho GDI) in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

A safeguard mechanism regulates Rho GTPases to coordinate cytokinesis with the establishment of cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

A GTP-exchange factor required for cell orientation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Proteome-wide protein interaction measurements of bacterial proteins of unknown function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Assembly of scaffold-mediated complexes containing Cdc42p, the exchange factor Cdc24p, and the effector Cla4p required for cell cycle-regulated phosphorylation of Cdc24p.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

A memory system of negative polarity cues prevents replicative aging.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Cdc42 regulation of kinase activity and signaling by the yeast p21-activated kinase Ste20.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Functional characterization of the Bag7, Lrg1 and Rgd2 RhoGAP proteins from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

protein kinase binding

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19073&geneProductId=UniProtKB:P19073

5 June 2018

Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19073&geneProductId=UniProtKB:P19073

5 June 2018

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19073&geneProductId=UniProtKB:P19073

incipient cellular bud site

IDA

fungal-type vacuole membrane

1 reference

14 February 2019

Daughter cell identity emerges from the interplay of Cdc42, septins, and exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

IDA

mating projection tip

intracellular anatomical structure

IDA

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19073&geneProductId=UniProtKB:P19073

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Subcellular localization of Cdc42p, a Saccharomyces cerevisiae GTP-binding protein involved in the control of cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

fungal-type vacuole membrane

3 references

14 February 2019

Saccharomyces cerevisiae Cdc42p localizes to cellular membranes and clusters at sites of polarized growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

regulation of exocyst localization

HDA

biological process

1 reference

14 February 2019

Cdc42 interacts with the exocyst and regulates polarized secretion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

establishment of cell polarity

1 reference

14 February 2019

A safeguard mechanism regulates Rho GTPases to coordinate cytokinesis with the establishment of cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

regulation of initiation of mating projection growth

1 reference

14 February 2019

Regulation of polarized growth initiation and termination cycles by the polarisome and Cdc42 regulators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

IEA

response to pheromone

1 reference

14 February 2019

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

pheromone-dependent signal transduction involved in conjugation with cellular fusion

IEA

small GTPase mediated signal transduction

IGI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

budding cell apical bud growth

IEA

1 reference

14 February 2019

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

regulation of exit from mitosis

1 reference

14 February 2019

A role for cell polarity proteins in mitotic exit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

septin ring organization

conjugation with cellular fusion

1 reference

14 February 2019

Cdc42p and Fus2p act together late in yeast cell fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

budding cell isotropic bud growth

1 reference

14 February 2019

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

positive regulation of pseudohyphal growth

1 reference

14 February 2019

Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

invasive growth in response to glucose limitation

1 reference

14 February 2019

Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

regulation of vacuole fusion, non-autophagic

1 reference

14 February 2019

Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

positive regulation of exocytosis

3 references

14 February 2019

The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

Cdc42 interacts with the exocyst and regulates polarized secretion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

14 February 2019

The Exo70 subunit of the exocyst is an effector for both Cdc42 and Rho3 function in polarized exocytosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

regulation of cell morphogenesis

IGI

1 reference

14 February 2019

Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

actin filament organization

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

establishment or maintenance of cell polarity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

Rho protein signal transduction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

regulation of cell shape

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

cell projection assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

actin cytoskeleton organization

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

Cdc42 protein signal transduction

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

regulation of actin cytoskeleton organization

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19073

small GTP-binding protein domain

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19073

Identifiers

MeSH descriptor ID

D020846

subject named as

cdc42 GTP-Binding Protein, Saccharomyces cerevisiae

0 references

MeSH tree code

D08.811.277.040.330.300.400.700.060

0 references

D12.776.157.325.515.700.050.500

0 references

D12.776.354.750.249

0 references

D12.776.476.338.400.700.060

0 references

1 reference

20 March 2022

1 reference

25 May 2022

1 reference