CCR4-NOT core exoribonuclease subunit CCR4 YAL021C (Q27550148)

http://www.ebi.ac.uk/interpro/protein/P31384

Leucine-rich repeat domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P31384

Endonuclease/exonuclease/phosphatase family

1 reference

Leucine-rich repeat, typical subtype, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

Leucine rich repeat 4, protein family

1 reference

Saccharomyces cerevisiae S288c

found in taxon

1 reference

25 May 2022

1 reference

25 May 2022

poly(A)-specific ribonuclease activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

3'-5'-exoribonuclease activity

4 references

8 April 2019

The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

8 April 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

8 April 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

8 April 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

10 references

9 May 2019

High-quality binary protein interaction map of the yeast interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

An in vivo map of the yeast protein interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

CCR4/NOT complex associates with the proteasome and regulates histone methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Functional organization of the yeast proteome by systematic analysis of protein complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

PUF proteins bind Pop2p to regulate messenger RNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Insights into the structure of the CCR4-NOT complex by electron microscopy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Dhh1p, a putative RNA helicase, associates with the general transcription factors Pop2p and Ccr4p from Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

3'-5'-exoribonuclease activity

IPI

5 references

9 May 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

A role for Q/N-rich aggregation-prone regions in P-body localization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

A complex containing RNA polymerase II, Paf1p, Cdc73p, Hpr1p, and Ccr4p plays a role in protein kinase C signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

CCR4-NOT core complex

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 reference

9 May 2019

Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

transcription, DNA-templated

IGI

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31384&geneProductId=UniProtKB:P31384

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

3 references

1 January 2018

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

SGD

S000000019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 January 2018

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

SGD

S000000019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

1 January 2018

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

SGD

S000000019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

nuclear-transcribed mRNA poly(A) tail shortening

IDA

3 references

8 April 2019

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

8 April 2019

Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

8 April 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

regulation of transcription by RNA polymerase II

IDA

1 reference

9 May 2019

The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

DNA replication checkpoint signaling

IPI

1 reference

9 May 2019

Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

replication fork protection

IGI

1 reference

9 May 2019

Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

positive regulation of transcription elongation from RNA polymerase II promoter

IGI

1 reference

9 May 2019

The multifunctional Ccr4-Not complex directly promotes transcription elongation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

traversing start control point of mitotic cell cycle

IDA

1 reference

9 May 2019

Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

regulation of transcription, DNA-templated

IMP

1 reference

27 February 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31384&geneProductId=UniProtKB:P31384

nucleic acid phosphodiester bond hydrolysis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

RNA phosphodiester bond hydrolysis, exonucleolytic

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

nuclear-transcribed mRNA poly(A) tail shortening

4 references

9 May 2019

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31384

IBA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference