RNA polymerase II subunit A C-terminal domain phosphatase YNL222W (Q27551720)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P53538

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

protein serine/threonine phosphatase activity

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

hydrolase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

1 reference

8 April 2019

phosphoprotein phosphatase activity

Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

RNA polymerase II CTD heptapeptide repeat phosphatase activity

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

27 March 2018

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

protein binding

5 references

8 April 2019

Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

The essential N terminus of the Pta1 scaffold protein is required for snoRNA transcription termination and Ssu72 function but is dispensable for pre-mRNA 3'-end processing.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Efficient mRNA polyadenylation requires a ubiquitin-like domain, a zinc knuckle, and a RING finger domain, all contained in the Mpe1 protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

RNA polymerase II CTD heptapeptide repeat phosphatase activity

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

protein tyrosine phosphatase activity

1 reference

8 April 2019

Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

cell component

nucleus

Functional interaction between Ssu72 and the Rpb2 subunit of RNA polymerase II in Saccharomyces cerevisiae

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Functional interaction between Ssu72 and the Rpb2 subunit of RNA polymerase II in Saccharomyces cerevisiae

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

mRNA cleavage and polyadenylation specificity factor complex

mRNA cleavage and polyadenylation specificity factor complex

A role for SSU72 in balancing RNA polymerase II transcription elongation and termination

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

transcription elongation from RNA polymerase II promoter

biological process

transcription initiation from RNA polymerase II promoter

IGI

dephosphorylation of RNA polymerase II C-terminal domain

IGI

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

27 March 2018

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53538&geneProductId=UniProtKB:P53538

termination of RNA polymerase II transcription, poly(A)-coupled

Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

mRNA 3'-end processing

1 reference

8 April 2019

Functional interactions between the transcription and mRNA 3′ end processing machineries mediated by Ssu72 and Sub1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

transcription antitermination

1 reference

8 April 2019

A role for SSU72 in balancing RNA polymerase II transcription elongation and termination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

transcriptional start site selection at RNA polymerase II promoter

Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

pre-mRNA cleavage required for polyadenylation

IGI

1 reference

8 April 2019

Functional interactions between the transcription and mRNA 3′ end processing machineries mediated by Ssu72 and Sub1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

termination of RNA polymerase II transcription

sno(s)RNA transcription

1 reference

8 April 2019

Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

termination of RNA polymerase II transcription, exosome-dependent

Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 protein mediates both poly(A)-coupled and poly(A)-independent termination of RNA polymerase II transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

mRNA polyadenylation

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

peptidyl-tyrosine dephosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

termination of RNA polymerase II transcription

Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

dephosphorylation of RNA polymerase II C-terminal domain

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53538

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference