NuA4 histone acetyltransferase complex catalytic subunit ESA1 YOR244W (Q27552891)

http://www.ebi.ac.uk/interpro/protein/Q08649

Winged helix-like DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q08649

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

H4 histone acetyltransferase activity

1 reference

27 March 2018

A conserved motif common to the histone acetyltransferase Esa1 and the histone deacetylase Rpd3.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

peptide N-acetyltransferase activity

1 reference

14 February 2019

Suppression analysis of esa1 mutants in Saccharomyces cerevisiae links NAB3 to transcriptional silencing and nucleolar functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

histone acetyltransferase activity

4 references

27 March 2018

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

27 March 2018

Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

12 references

14 February 2019

Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

MYST protein acetyltransferase activity requires active site lysine autoacetylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

A global protein kinase and phosphatase interaction network in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Defining the budding yeast chromatin-associated interactome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Eaf5/7/3 form a functionally independent NuA4 submodule linked to RNA polymerase II-coupled nucleosome recycling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

histone acetyltransferase activity

IPI

5 references

14 February 2019

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

Piccolo NuA4 histone acetyltransferase complex

cell component

1 reference

27 March 2018

Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

NuA4 histone acetyltransferase complex

4 references

14 February 2019

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

histone acetyltransferase complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

positive regulation of macroautophagy

biological process

1 reference

14 February 2019

Function and molecular mechanism of acetylation in autophagy regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

3 references

14 February 2019

Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

A moonlighting metabolic protein influences repair at DNA double-stranded breaks.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

transcription, DNA-templated

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08649&geneProductId=UniProtKB:Q08649

DNA-templated transcription, elongation

regulation of transcription by RNA polymerase II

1 reference

14 February 2019

The yeast NuA4 and Drosophila MSL complexes contain homologous subunits important for transcription regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

peptidyl-lysine acetylation

1 reference

14 February 2019

Suppression analysis of esa1 mutants in Saccharomyces cerevisiae links NAB3 to transcriptional silencing and nucleolar functions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

positive regulation of transcription elongation from RNA polymerase II promoter

rDNA heterochromatin assembly

IGI

Esa1p is an essential histone acetyltransferase required for cell cycle progression

IGI

regulation of cell cycle

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

histone H4 acetylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

Esa1p is an essential histone acetyltransferase required for cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

14 February 2019

NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

chromatin organization

1 reference

14 February 2019

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08649

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference