A functional hot spot for antigen recognition in a superagonist TCR/MHC complex (Q27622127)

3

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author name string

K C Garcia

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M G Rudolph

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L Teyton

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I A Wilson

Complementary mutations in an antigenic peptide allow for crossreactivity of autoreactive T-cell clones

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language of work or name

English

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publication date

March 2000

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published in

Immunity

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volume

12

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issue

3

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page(s)

251-61

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

A hot spot of binding energy in a hormone-receptor interface

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Analytical molecular surface calculation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Visualization of CD2 interaction with LFA-3 and determination of the two-dimensional dissociation constant for adhesion receptors in a contact area.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Amino acid homology between the encephalitogenic site of myelin basic protein and virus: mechanism for autoimmunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Structural basis of T cell recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Differential thymic selection outcomes stimulated by focal structural alteration in peptide/major histocompatibility complex ligands

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

The regulation and function of p21ras during T-cell activation and growth.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Structure and specificity of the anti-digoxin antibody 40-50

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

26-10 Fab-digoxin complex: affinity and specificity due to surface complementarity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Essential flexibility in the T-cell recognition of antigen

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

SURFNET: a program for visualizing molecular surfaces, cavities, and intermolecular interactions

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Shape complementarity at protein/protein interfaces

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

AMoRe: an automated package for molecular replacement

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Molecular mimicry and autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

A piston model for transmembrane signaling of the aspartate receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Altered T cell receptor ligands trigger a subset of early T cell signals

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Improved Fourier coefficients for maps using phases from partial structures with errors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Ligand-specific oligomerization of T-cell receptor molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

The crystal structure of a T cell receptor in complex with peptide and MHC class II

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

A kinetic basis for T cell receptor repertoire selection during an immune response

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Altered peptide ligand-induced partial T cell activation: molecular mechanisms and role in T cell biology

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Efficiency of signalling through cytokine receptors depends critically on receptor orientation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

A single T cell receptor recognizes structurally distinct MHC/peptide complexes with high specificity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Identification of a common docking topology with substantial variation among different TCR-peptide-MHC complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

The affinity maturation of anti-4-hydroxy-3-nitrophenylacetyl mouse monoclonal antibody. A calorimetric study of the antigen-antibody interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Signal transduction by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Binding in the growth hormone receptor complex

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Perspectives: protein structure. Class-conscious TCR?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

The structure, organization, activation and plasticity of the erythropoietin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2980178-8

7 January 2021