Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors (Q27625231)

2

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M H Lambert

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A B Miller

4

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R K Bledsoe

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M V Milburn

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S A Kliewer

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T M Willson

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H E Xu

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

9

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language of work or name

English

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publication date

March 2000

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published in

Molecular Cell

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volume

5

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issue

3

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page(s)

545-55

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cites work

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Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains

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A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat

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Solvent-accessible surfaces of proteins and nucleic acids

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

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Increasing the complexity of coactivation in nuclear receptor signaling

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N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents

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Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

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The nuclear receptor PPARgamma - bigger than fat

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9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

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The RXR heterodimers and orphan receptors

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

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A unified nomenclature system for the nuclear receptor superfamily

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Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR

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Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid

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Transactivation by retinoid X receptor-peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimers: intermolecular synergy requires only the PPARgamma hormone-dependent activation function

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PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

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Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

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