'pH-jump' crystallographic analyses of gamma-lactam-porcine pancreatic elastase complexes (Q27627388)

1

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R C Wilmouth

2

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I J Clifton

3

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C J Schofield

Mechanistic insights into the inhibition of serine proteases by monocyclic lactams

4

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language of work or name

English

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publication date

15 October 2000

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published in

Biochemical Journal

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volume

351 Pt 2

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page(s)

335-40

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cites work

1 reference

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Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex

20 March 2017

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Novel natural product 5,5-trans-lactone inhibitors of human alpha-thrombin: mechanism of action and structural studies

20 March 2017

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Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase

20 March 2017

1 reference

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Structure of native porcine pancreatic elastase at 1.65 A resolutions

20 March 2017

1 reference

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Raster3D Version 2.0. A program for photorealistic molecular graphics

20 March 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

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Energy considerations show that low-barrier hydrogen bonds do not offer a catalytic advantage over ordinary hydrogen bonds

20 March 2017

1 reference

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A low-barrier hydrogen bond in the catalytic triad of serine proteases

20 March 2017

1 reference

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Specificity, stability, and potency of monocyclic beta-lactam inhibitors of human leucocyte elastase

20 March 2017

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The low barrier hydrogen bond in enzymatic catalysis.

2 June 2018

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Inhibition of human serine proteases by substituted 2-azetidinones

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11023818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

7-alkylidenecephalosporin esters as inhibitors of human leukocyte elastase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11023818

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Occurrence of a serine residue in the penicillin-binding site of the exocellular DD-carboxy-peptidase-transpeptidase from Streptomyces R61

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11023818