A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery (Q27629471)

2

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N Sonenberg

3

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T V Pestova

4

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C U Hellen

5

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S K Burley

HEAT repeats in the Huntington's disease protein

6

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language of work or name

English

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publication date

January 2001

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published in

Molecular Cell

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volume

7

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issue

1

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page(s)

193-203

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cites work

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Translation initiation factor eIF-4gamma is encoded by an amplified gene and induces an immune response in squamous cell lung carcinoma

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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

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Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp

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7 January 2021

Structure of importin-beta bound to the IBB domain of importin-alpha

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Degradation of eukaryotic polypeptide chain initiation factor (eIF) 4G in response to induction of apoptosis in human lymphoma cell lines

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7 January 2021

Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

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7 January 2021

Translation driven by an eIF4G core domain in vivo

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[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

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Recognition of polyadenylate RNA by the poly(A)-binding protein

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Separation of protein synthesis initiation factor eIF4A from a p220-associated cap binding complex activity

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7 January 2021

Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

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7 January 2021

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

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7 January 2021

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

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TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function

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7 January 2021

A novel functional human eukaryotic translation initiation factor 4G

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7 January 2021

The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs

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7 January 2021

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E

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7 January 2021

Determination of macromolecular structures from anomalous diffraction of synchrotron radiation

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eIF4G: a multipurpose ribosome adapter?

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7 January 2021

Protein structure comparison by alignment of distance matrices

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7 January 2021

Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A

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7 January 2021

A new translational regulator with homology to eukaryotic translation initiation factor 4G

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7 January 2021

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation

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7 January 2021

A segment of the 5' nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation

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7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

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7 January 2021

Translation eukaryotic initiation factor 4G recognizes a specific structural element within the internal ribosome entry site of encephalomyocarditis virus RNA.

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7 January 2021

Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiation

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7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

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7 January 2021

DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death

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7 January 2021

Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation

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7 January 2021

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

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7 January 2021

Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP

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7 January 2021

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

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7 January 2021

Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region

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7 January 2021

Eukaryotic translation initiation factors 4G and 4A from Saccharomyces cerevisiae interact physically and functionally

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7 January 2021

The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E.

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7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

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7 January 2021

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

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7 January 2021

Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA

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7 January 2021

Canonical eukaryotic initiation factors determine initiation of translation by internal ribosomal entry

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7 January 2021

Functional dissection of eukaryotic initiation factor 4F: the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes

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7 January 2021

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

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7 January 2021

Database of homology-derived protein structures and the structural meaning of sequence alignment

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7 January 2021

cDNA cloning, expression analysis, and chromosomal localization of a gene with high homology to wheat eIF-(iso)4F and mammalian eIF-4G.

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7 January 2021

Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G

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7 January 2021

A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme

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7 January 2021